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hrpA

Victor ID 2209
Gene Name hrpA
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 961000
NCBI Protein GI 15801734
Locus Tag Z2313
Genbank Accession AE005174
Protein Accession NP_287752
Other Database IDs UniProtKB-ID: Q8X9T0_ECO57
UniRef100: UniRef100_C3TB23
UniRef90: UniRef90_P43329
UniRef50: UniRef50_P43329
UniParc: UPI00000D07AA
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG56366.1
EMBL-CDS: BAB35438.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000027641.
EnsemblGenome_TRS: EBESCT00000028590
EnsemblGenome_PRO: EBESCP00000027483
EnsemblGenome: EBESCG00000056514.
EnsemblGenome_TRS: EBESCT00000057466
EnsemblGenome_PRO: EBESCP00000055294
GenomeReviews: AE005174_GR
GenomeRev
Taxonomy ID 155864
Gene Starting Position 2085684
Gene Ending Position 2089529
Gene Strand (Orientation) -
Protein Name ATP-dependent RNA helicase HrpA
Protein pI 7.72
Protein Weight 138593.44
Protein Length 1281
Protein Note involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain
DNA Sequence 
>gi|16445223:2085684-2089529 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
GTTAACCGCTAATCTGCTCCATCGCCTGCAAAATACGCTTATCTGAAATCGGATAAGGCGTACCAAGTTG
TTGAGCGAAGTAACTAACGCGCAGCTCTTCTATCATCCAACGGATCTCTTTCACGTCTTCATCCTCACGA
CGTGCAGGCGGGAGTTTGTTGAACCATTGCTGCCACGCCTGCTGGACGTTTTCGACTTTCAGCATCTGTG
CACGATCGCGATGTGGATCAACCGCCAGTTTTTCCAGCCGTTTTTCAATCGCCTGCAAATAACGCAGCGT
GTCGCCCAGCCGTTTGAAGCCGTTACCAGTGACAAAACCGCGATATACCAACCCGCCCATCTGCGCTTTA
ATGTCAGAAAGCCCCAGCGCCATGGTCATATCCACCCGCCCTTTCAGACGTTTGTTGATATTGAACACTG
CCGTAAGGATTTGCTCGACCTGCTTCGCAATATCCACCACCGTGTCGTTCAGTTCGGCACGCACTTTTTC
ATGCAGCGCAGCAAAGCCTTCTTCCGTCCAGACCGGGCCTCCATTGGCGTCGATCAGTTGATCCACACCG
CATGAGATACAGTCGTCGATCAGCTCCAGCACTTTGCCATACGGGTTAAAGTACAGCCCCAGCTTGGCTT
TGTTTGGTAACTTCTCATGTAAATACTTGATTGGTGAGGGAATATTCAGCAGCAGTAGACGGCGAAGACC
GTTCCACATTGCCTGTTTTTGCTCCAGCGGGTTATCAAACAGTTTGATCGCCACACTGTCGCGCTCATCC
ACCAGCGCCGGCCACGCCTTCACTTTGTAGTTACCACGCTTCTGTTCGTAGCTTTCCGGCAACTGACCAA
AACTCCAGATATGTAAGCCGCTCTGCTCGATACCGTCATCCGCCACCGCAGATAGCGTTTCCTGCACTTT
GCCTTTCAGCGCATCTTTCAGATCTTGTAGCGAGCGCCCTTCTTTTAGCTTCTTGTTTTTGTCATCCACC
ACGCGGAAGGTGATTTTCAGGTGATCGGGCACCTGATCCCAGTGCCAGTCTTCGCGGTCAACGGTAACGC
CGGTCATCCGCCGTAACTCGCGCTCAAGGCTGTCGAGCAACGGTAACTCCAGCGGTGTGACGCGGCCTAA
AAACGCTTCGGCATAGTTTGGCGCAGGTACAAAATTACGGCGTACCGGTTTCGGCAACGATTTAATCAGA
GCAATCACCAGTTCGCGGCGCAGACCAGGGATCTGCCATTCAAACCCGCTTTCCTCAACCTGGTTAAGTA
ACGGCAGCGGAATATGTACGGTCACACCGTCAGCATCCGCGCCGGGCTCAAACTGATAGCTCAAACGCAG
CTTGAGATTGCCCTGATGCCAGAAGTTCGGGTAATCCAGCTTGCTGATCTTTTCCGCCCCTTCTTTGATC
AACATGCTCTTTTCAAAGTTGAGCAAATCAGGCGTTTCGCGGCTGACTTTTTTCCACCAGCTGTCGAAGT
GACGAGCGGAGATTACATCGTGGCCGATGCGCTGGTCGTAGAACTCAAACAGCGTTTCGTCATCAACCAG
AATATCGCGGCGACGTGATTTGTGTTCAAGCTCTTCCACTTCGGCCCGCAGTTTCAGGTTTTCACGGAAG
AATGCGTGACGCGTCTGCCAGTCACCTTCCACCAGCGCGTGGCGAATAAAGAGTTCACGACATAACGCCG
GATCGATCTGGCTGTAGTTGACCTTGCGCGCGGCAACAATCGGCAAACCATAAACAGTGACTTTTTCCGT
TGCCATCACCGCGCCCTGCGCCCGTTCCCAGTGCGGTTCGCTGTAGGTACGTTTAATCAAATGCTGAGCG
ACAGGCTCCACCCATTCCGGGTCGATACGCGCAGCAATGCGCCCCCACAGGCGGCTGGTTTCTACCAGTT
CCGCCACCATTACCCATTTCGGCGGTTTTTTGAATAAACCAGAACCGGGGAAGATGGAGAAACGCGCGTT
ACGTGCGCCGGTATATTCTTGTTTATCGGCATCTTTCATGCCGATATGGGAAAGCAACCCCGTCAGCAAC
GCAATGTGAATTTCACGATACTCCGCCGGTTCGCTGTTCACCGGAATGCCGAGTTCTTTCACCACCTGGC
GCAACTGGGTGTAGATATCCTGCCATTCGCGCACACGCAGATAGTTGAGATAATCGGTACGACACAGGCG
ACGGAAGGCGTTGGAAGAAAGCGCCTTTTGCTGCTCGCCAAGATAATTCCACAGATTCACAAACGCGAGG
AAGTCAGACTCTTTGTCGTGGAAGCGACGATGTTTTTCGTCCGATGCCTGCTGTTTGTCCATCGGACGTT
CGCGCGGATCCTGAATGGAGAGCGCAGACGTGATAATCATCGCCTCACGCACGCAGCCATGTTTTTGCGC
TTCCAGCACCATACGCGCCAGACGTGGGTCGACAGGCAACTGCGAGAGCTGGCGACCGAGCGGCGTCAGT
TTATAGGCGCTGGCCTGTTCATCCGTGGTGATCGCGCCCAGTTCTTCGAGCAGACGCACGCCATCCTGGA
TATTGCGTTTATCCGGTGCTTCGACAAACGGGAACGCAGCGATATCGCCTAGCCCCAGCGCGGTCATCTG
CAAAATAACCGAGGCCAGGTTGGTACGCAGAATCTCCGGATCGGTAAACTCCGGGCGCGAGAGGAAATCG
TCTTCGGAATAGAGACGAATACAGATCCCTTCGGACACACGACCACAGCGGCCTTTACGCTGATTGGCAG
ACGCCTGCGAAATGGGCTCAATCGGCAAACGCTGCACTTTGGTGCGATAGCTGTAGCGGCTGATACGCGC
CGTACCGGGGTCGATAACGTATTTAATCCCCGGTACAGTCAGCGAGGTTTCCGCGACGTTGGTCGCCAGC
ACAATGCGTCGCCCGCTGTGCGACTGGAACACGCGGTTCTGTTCGCTATTCGAAAGCCGCGCATAAAGCG
GCAAGATTTCGGTATGGCGTAAGTTCAGCTTGTTCAGCGCATCGGCGGTATCGCGAATTTCCCGCTCGCC
GCTCATAAAGATCAGAATGTCGCCGGGGCTTTCCTGGCTTAGTTCGTCCACGGCATCGAAAATTGCCTGC
AACTGGTCGCGCTCAGTGTCGTCGGCTTCTTCAACAATCGGGCGATAGCGCACTTCCACCGGATAGGTCC
GACCGGAGACTTCAATAATCGGCGCATTATTAAAGTGGCGCGAAAAGCGTTCCGGGTCGATAGTCGCGGA
AGTGATAATGATTTTTAGGTCAGGACGCCGCGGCAGCAACTCTTTCAAATAACCGAGCAGAAAATCGATA
TTCAGGCTACGTTCGTGCGCTTCGTCAATAATGATAGTGTCGTACTGCATCAGCAGGCGGTCTTGCTGGA
TCTCCGCCAGCAGGATACCGTCGGTCATTAGCTTGACCATCGTGTTATCACTTACGTGATCGCTGAAACG
CACTTTGTAACCGATGCAACCGCCCGGCTCCGTTTTCAGCTCTTCCGCAATACGGTTCGCTACCGTTCTT
GCCGCCAGGCGACGCGGCTGGGTATGGCCGATCAGCCCTTTAATCCCGCGCCCCAGCTCCATACAGATTT
TCGGTAACTGAGTCGTTTTACCAGAACCCGTTTCCCCGGCGACTATCACCACCTGGTGATCACGAATCGC
TTCGAGAATGTCCTGTTTTTTCTGACTAACCGGCAAATTGTCAGGATAAGTAATTTCCGGTCGTGCCGCT
TCACGCAGCAGGACTTTCCCTGCCGCCTGGTCAATCTCTTTCGCCATCTCCTGGAAAATGGCCTGTTGTG
CATCAGGATTTTTAACCTTCTTCACGCCGTGCAGACGGCGAGAAAAACGCAGTCTGTCACGCAGCA
Protein Sequence 
>gi|15801734|ref|NP_287752.1| ATP-dependent RNA helicase HrpA [Escherichia coli O157:H7 str. EDL933]
MLRDRLRFSRRLHGVKKVKNPDAQQAIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEA
IRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVR
FSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITS
ATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQAIFDAVDELSQESPGDILIFMSG
EREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTA
RISRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQ
MTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEA
QKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSNAFRR
LCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIGMKDADKQEYTGARN
ARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMAT
EKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDIL
VDDETLFEFYDQRIGHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKL
RLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFL
GRVTPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKITFRVVDDKNKKLKEGRSLQDLKDALKGK
VQETLSAVADDGIEQSGLHIWSFGQLPESYEQKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNG
LRRLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTEEGFAALHE
KVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFKRLGDT
LRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWFNKLPPARREDEDVKEIRWMIEELRVSYFAQQ
LGTPYPISDKRILQAMEQISG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hrpA mutant is attenuated in calves (Dziva et al., 2004).
COG COG1643L, under L: Replication, recombination and repair
References
Dziva et al., 2004: Dziva F, van Diemen PM, Stevens MP, Smith AJ, Wallis TS. Identification of Escherichia coli O157 : H7 genes influencing colonization of the bovine gastrointestinal tract using signature-tagged mutagenesis. Microbiology (Reading, England). 2004; 150(Pt 11); 3631-3645. [PubMed: 15528651].