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espD from Escherichia coli O157:H7 str. EDL933

Victor ID 2204
Gene Name espD from Escherichia coli O157:H7 str. EDL933
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 960866
NCBI Protein GI 15804216
Locus Tag Z5106
Protein Accession NP_290255.1
Other Database IDs UniProtKB-ID: Q7DB81_ECO57
UniRef100: UniRef100_O85626
UniRef90: UniRef90_O85626
UniRef50: UniRef50_P71215
UniParc: UPI00000D00E7
EMBL: AE005174
EMBL: EU871626
EMBL: BA000007
EMBL-CDS: AAG58819.1
EMBL-CDS: ACG59617.1
EMBL-CDS: BAB37978.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000027629.
EnsemblGenome_TRS: EBESCT00000028578
EnsemblGenome_PRO: EBESCP00000027471
EnsemblGenome: EBESCG00000058698.
EnsemblGenome_TRS: EBESCT00000059651
EnsemblGenome_PRO: EBESCP00000057479
Taxonomy ID 155864
Gene Starting Position 4660984
Gene Ending Position 4662108
Gene Strand (Orientation) -
Protein Name secreted protein EspD
DNA Sequence 
>gi|16445223:4660984-4662108 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
ATTAAATTCGGCCACTAACAATACGACTATTTACCCGTGCTGAATCGGACATCAGTTGAGAAACACTTTG
TAAATAGCTCGCCTGATTTTGTAACTCGCTTGCCGCTTTATCCAGCTCGAGCTTCGCACTCTCACCTAAG
CTTTCACTCTGTCGAGTTAAGTTTTGCACCGCGAAAGCAGCTAACTGAGACAACATTTGGAGTTGCGCAG
CCTCATTATTCAACGCAGTTGTCCCGGCAGAACGAATACCGTTCGTAACGCCCTCAGCCACTGTCGAAAT
TTTTGCAAAAACGTTTTTAACCAGCGCTTCTGCCGCCTTCTCAACGACTTTTACAACGCTTGAGCCAATT
TTGTTAGCAACATTACCAAATTTAGATAACAGTGAAGACACCCCGCCAACGCCGGCTGTCAGAATGCTTG
CGGCCATAGATATTCCGCCAAAGACCTGTGCTGCAGTCTTTAATCCCTGAGGGGCATTTTCCCCCATTAC
ATCGACTGCCGTTTGCAGTGCCATTGCTGTTGCACCAATGGCAACAACAGCCCAGAGTGCTGGGTTAAAA
ACAGCGGCAACGGCTGTTAATGCGACGCCCAACCAACCAAAGACCTGGCCAACAATTTTACTTTTTTGTG
ATTTCTCTTCGGCTTTCTGTTGTTCTTCGAGCTGTTTTTTATACTCCTGCGTTTTATTCTCCAGCGCTTT
AGTTTGCCCATCCATATAAATCTCGTTAGAGTTTTTCAGACTCGAGACTTTCTGCGCGGAAGTATCCAGG
GATAACAGAGTGACCATCATCATCATTTGCTGAGGGTCAACGGTATTCACCTGAGAGAGATAGGGATAGC
TTGTGCGCTGTGGCTCTGCCTCCTCAGTGCGACTTGTAACCTCACCACTAATACCACCAAACAATTTACT
AAGGACATCCTCAGCAGCAGAGGGCGTCACTAATGAGTGACCTGCCGGCGGCGTCGGTAAAGGGCTACTT
TCTGTCCAGCCTGCTGACGAGTTCATGGATTTAACCAGTTGTAAATCCAGCGATAAACCCGTTTCAGATT
GAGTAATACCAGAAGTACCCGAGGCGGTATTAACCCCAGACGTTACAGACAGGGTATCGTTATTTACGTT
AAGCA
Protein Sequence 
>gi|15804216|ref|NP_290255.1| hypothetical protein Z5106 [Escherichia coli O157:H7 str. EDL933] MLNVNNDTLSVTSGVNTASGTSGITQSETGLSLDLQLVKSMNSSAGWTESSPLPTPPAGHSLVTPSAAEDVLSKLFGGISGEVTSRTEEAEPQRTSYPYLSQVNTVDPQQMMMMVTLLSLDTSAQKVSSLKNSNEIYMDGQTKALENKTQEYKKQLEEQQKAEEKSQKSKIVGQVFGWLGVALTAVAAVFNPALWAVVAIGATAMALQTAVDVMGENAPQGLKTAAQVFGGISMAASILTAGVGGVSSLLSKFGNVANKIGSSVVKVVEKAAEALVKNVFAKISTVAEGVTNGIRSAGTTALNNEAAQLQMLSQLAAFAVQNLTRQSESLGESAKLELDKAASELQNQASYLQSVSQLMSDSARVNSRIVSGRI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: espD deletion mutant of the enterohemorrhagic E. coli (EHEC) strain EDL933 had impaired attachment to HeLa cells (Kresse et al., 1999).
COG COG5613S, under S: Function unknown
References
Kresse et al., 1999: Kresse AU, Rohde M, Guzmán CA. The EspD protein of enterohemorrhagic Escherichia coli is required for the formation of bacterial surface appendages and is incorporated in the cytoplasmic membranes of target cells. Infection and immunity. 1999; 67(9); 4834-4842. [PubMed: 10456938].