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escN from Escherichia coli O157:H7 str. EDL933

Victor ID 2198
Gene Name escN from Escherichia coli O157:H7 str. EDL933
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 960853
NCBI Protein GI 15804229
Locus Tag Z5119
Protein Accession NP_290268.1
Other Database IDs UniProtKB-ID: Q7DB71_ECO57
UniRef100: UniRef100_O85632
UniRef90: UniRef90_O85632
UniRef50: UniRef50_O85632
UniParc: UPI00000D00BB
EMBL: AE005174
EMBL: EU871626
EMBL: BA000007
EMBL-CDS: AAG58832.1
EMBL-CDS: ACG59630.1
EMBL-CDS: BAB37991.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000023488.
EnsemblGenome_TRS: EBESCT00000024434
EnsemblGenome_PRO: EBESCP00000023327
EnsemblGenome: EBESCG00000058206.
EnsemblGenome_TRS: EBESCT00000059158
EnsemblGenome_PRO: EBESCP00000056986
Taxonomy ID 155864
Gene Starting Position 4674676
Gene Ending Position 4676016
Gene Strand (Orientation) -
Protein Name escN
DNA Sequence 
>gi|16445223:4674676-4676016 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
CTCAGGCAACCACTTTGAATAGGCTTTCAATCGTTTTTTCGTAACTACTGATATCTTTGGTGCTTTGTTG
TATAAAGTTCTGAATTAATTTCCTATTTTTTATTGCCTTATCTGCTTCAGGATCTTGCCCCATCGTGTAC
TCACCAATACGAATAAGCAGCTCAACATTTTTATAAGTTGCAATAAGCTTTTTGCATTCTGCCGCCGCAC
GCAAATGCTCCGATGTAACAACGTTATGCATAACACGACTGGCACTTAAACCAATATCAATTGCAGGGAA
ATGGTTTTCCTCTGCAAGTTCTCGGGTAAGTACGATGTGCCCATCAAGAATAGAGCGGACTTCATCGCCA
ATAGGATCATTAACATTATCGCTTTCTAACAACACCGTATAAATCGCGGTTATTGAACCTTTTGGCGCAG
GCCCCGCTCGCTCTAATAATTTGGGTAACGAAGAAAAAACACTCGGAGGGAATCCCCCCCTTACATCAGG
TTCTCCCGATGCAAGCCCAACATCACGTGCGGCTCGGGCATAACGAGTTACAGAATCCATCATTAATAAT
ACATTTTTACCTTGATCGCGGAAGTACTCTGCAATAGTCGTCGCCGTAAATGCGGCTTTCATCCTTTCCA
GCGCGGGGCGGTCTGACGTTGTGACGACCAGTACACATTTAGAAAGCGTGGATTGAGGTAAGAGCGCGAG
GAATTCATTTACTTCGCGACCACGTTCGCCGATAAGAGCAAGGACAATAATATCTGCGGATGCGCCATTA
CAAATCATCCCCAAAAGCGTACTTTTACCAACGCCTGAACCAGCAAAAATACCGATACGCTGCCCAATAC
CGCAAGTTAGTAGCCCATCAATTGCCCTGACGCCAAGTATAAATGGCTGATCAATAACCTGCCTTAATAA
AGGATCTGGTGGTTCAGCATACAAGCTGCGTTCAAACGGAAGATAGGGGGCAGCAATATTACTCTCCATT
GGTCTGCCTATGCCATCAACAAGCCGCCCAAGTAGTGCGTCTCCAACACGAATCTTGAACTCATCTCCCT
GATAACTTAACCACTGACCACAGTACATGCCGGAAACATGCTCAAAAGGCAACAAGAAAACCTCATCTTC
ATCAATAGCGATCACCTCGGCTAAACGTTGACTGGGTTCTATCTTATAAAAGGCGCCAATACGCGCTTTT
GGTAAACGCGCCTTAATAATCGTCCCGCCGATATTGATAATCTTGCCTTCATATCTGGTAGACGAATTTA
ATGATAATGCCGGCACAGTGCTATTGAGCACTTTCTGAATACGTGGGTATTTTTCCAATACAGAATCATG
CTCTGAAATCA
Protein Sequence 
>gi|15804229|ref|NP_290268.1| hypothetical protein Z5119 [Escherichia coli O157:H7 str. EDL933] MISEHDSVLEKYPRIQKVLNSTVPALSLNSSTRYEGKIINIGGTIIKARLPKARIGAFYKIEPSQRLAEVIAIDEDEVFLLPFEHVSGMYCGQWLSYQGDEFKIRVGDALLGRLVDGIGRPMESNIAAPYLPFERSLYAEPPDPLLRQVIDQPFILGVRAIDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALLPQSTLSKCVLVVTTSDRPALERMKAAFTATTIAEYFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKLLERAGPAPKGSITAIYTVLLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRAAAECKKLIATYKNVELLIRIGEYTMGQDPEADKAIKNRKLIQNFIQQSTKDISSYEKTIESLFKVVA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion of escN abolished pathogenicity in infant rabbits compared to wild-type EHEC (Ritchie and Waldor, 2005).
COG COG1157NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Ritchie and Waldor, 2005: Ritchie JM, Waldor MK. The locus of enterocyte effacement-encoded effector proteins all promote enterohemorrhagic Escherichia coli pathogenicity in infant rabbits. Infection and immunity. 2005; 73(3); 1466-1474. [PubMed: 15731044].