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Z2207

Victor ID 2190
Gene Name Z2207
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 960666
NCBI Protein GI 15801637
Locus Tag Z2207
Genbank Accession AE005174
Protein Accession NP_287654
Other Database IDs UniProtKB-ID: YDEP_ECO57
UniRef100: UniRef100_Q8XAX1
UniRef90: UniRef90_Q83RF3
UniRef50: UniRef50_P77561
UniParc: UPI00000D066A
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG56267.1
EMBL-CDS: BAB35529.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000025736
EnsemblGenome_TRS: EBESCT00000026683
EnsemblGenome_PRO: EBESCP00000025576
EnsemblGenome: EBESCG00000058750
EnsemblGenome_TRS: EBESCT00000059703
EnsemblGenome_PRO: EBESCP00000057531
GenomeReviews: AE005174_GR
GenomeReviews
Taxonomy ID 155864
Gene Starting Position 1980740
Gene Ending Position 1983019
Gene Strand (Orientation) +
Protein Name putative oxidoreductase
Protein pI 6.76
Protein Weight 78706.266
Protein Length 759
Protein Note in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family
DNA Sequence 
>gi|16445223:1980740-1983019 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
GATGAAGAAAAAAATTGAATCCTACCAGGGTGCTGCCGGTGGTTGGGGTGCTGTTAAATCCGTAGCGAAT
GCAGTACGTAAGCAGATGGATATACGCCAGGATGTTATTGCCATGTTTGACATGAATAAGCCAGAGGGCT
TTGACTGTCCGGGTTGTGCATGGCCAGATCCTAAGCACAGTGCGTCATTCGACATTTGTGAAAACGGCGC
AAAAGCAATCGCCTGGGAAGTCACGGATAAGCAGGTAAATGCCTCTTTCTTTGCTCAGAATACGGTTCAA
TCATTACTTACCTGGGGAGATCACGAGCTTGAGGCTGCGGGACGTCTCACTCAGCCTTTGAAATATGATG
CTGTCAGCGACTGTTACAAGCCATTAAGCTGGCAACAAGCTTTCGACGAAATTGGCGCACGCCTTCAAAG
CTATAGTGATCCCAATCAGGTTGAATTCTATACTTCGGGCCGCACTTCCAATGAAGCTGCCTTTCTTTAT
CAGCTTTTTGCCCGTGAATACGGGAGCAATAACTTTCCCGACTGCTCCAACATGTGCCATGAACCGACAA
GCGTGGGTTTGGCAGCGAGTATCGGTGTAGGTAAAGGGACCGTGTTGCTGGAAGACTTTGAGAAGTGCGA
TTTAGTCATTTGCATTGGGCATAACCCTGGTACAAACCACCCTCGCATGCTGACTTCGTTGCGCGCTTTA
GTGAAACGGGGAGCGAAAATGATCGCCATCAATCCTCTACAGGAACGTGGCCTGGAGCGATTTACCGCAC
CGCAAAACCCGTTTGAAATGCTGACGAACTCTGAGACTCAGTTGGCCAGTGCCTACTATAACGTGCGCAT
TGGTGGTGATATGGCGTTGCTCAAGGGGATGATGCGCCTGTTAATTGAGCGCGATGATGCTGCAAGCGCC
GCAGGTCGGCCCTCATTGCTGGATGACGAATTTATTCAAACGCATACCGTCGGCTTTGACGAGCTACGCC
GTGACGTGCTCAATTCCGAGTGGAAAGATATCGAACGTATTTCTGGACTAAGTCAGACACAAATCGCCGA
ACTGGCTGATGCATATGCCGCTGCCGAACGAACCATTATCTGTTACGGAATGGGGATCACTCAGCACGAA
CATGGTACCCAGAATGTACAGCAACTGGTCAATCTGCTGTTGATGAAAGGTAACATTGGCAAGCCTGGTG
CGGGTATCTGCCCACTACGTGGCCACTCTAATGTACAGGGCGACCGAACCGTCGGTATCACCGAGAAACC
GTCTGTAGAGTTTCTGGCTCGCCTGGGTGAGCGCTATGGCTTCACCCCACCTCATGTACCTGGACATGCT
GCAATTGCCAGCATGCAAGCAATATGTACGGGGCAGGCTCGAGCATTGATCTGCATGGGGGGCAACTTTG
CACTGGCAATGCCAGATCGGGAAGCGAGCGCTGTACCGTTAACGCAATTAGATTTGGCGGTACACGTAGC
CACTAAGCTTAACCGCTCTCATCTGCTGACCGCACGGCATAGCTATATTCTGCCGGTTCTGGGACGTAGC
GAGATTGACATGCAAAAAAGCGGTGCGCAGGCGGTAACCGTTGAGGATTCAATGTCGATGATTCATGCCT
CGCGTGGCGTGTTAAAACCCGCCGGTGTAATGCTGAAATCAGAGTGTGCTGTGGTCGCGGGAATCGCGCA
GGCAACACTACCCCAGAGCGTGGTAGCCTGGGAGTATCTGGTGGAAGATTATGATCGCATTCGCAATGAC
ATTGAAGCTGTGCTGCCAGAGTTCGCCGMCTATAACCAACGCATCCGTCATCCCGGTGGTTTTCACCTGA
TAAATGCAGCTGCTGAAAGGCGCTGGATGACGCCGTCAGGTAAGGCTAATTTCATTACCAGCAAAGGGCT
GTTAGAAGATCCCTCTTCAGCGTTTAACAGTAAGCTGGTCATGGCGACAGTACSCAGCCACGATCAGTAC
AACACGACGATTTATGGTATGGATGATCGCTATCGAGGGGTATTCGGTCAACGAGATGTGGTCTTTATGA
GTGCTAAACAAGCTAAAATTTGCCGTGTAAAAAACGGCGAARGAGTTAATCTTATTGCGCTTACGCCAGA
CGGTAAGCGCAGCTCACGCCGCATGGATAGATTAAAAGTGGTCATTTACCCTATGGCTGACCGCTCACTG
GTGACCTATTTTCCAGAATCGAATCACATGCTAACACTTGATAACCACGATCCATTAAGTGGCATTCCTG
GCTATAAAAGTATTCCGGTTGAATTAGAACCATCAAATTA
Protein Sequence 
>gi|15801637|ref|NP_287654.1| putative oxidoreductase [Escherichia coli O157:H7 str. EDL933]
MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKPEGFDCPGCAWPDPKHSASFDICENGA
KAIAWEVTDKQVNASFFAQNTVQSLLTWGDHELEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQS
YSDPNQVEFYTSGRTSNEAAFLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCD
LVICIGHNPGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYYNVRI
GGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEWKDIERISGLSQTQIAE
LADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNIGKPGAGICPLRGHSNVQGDRTVGITEKP
SVEFLARLGERYGFTPPHVPGHAAIASMQAICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVA
TKLNRSHLLTARHSYILPVLGRSEIDMQKSGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQ
ATLPQSVVAWEYLVEDYDRIRNDIEAVLPEFAXYNQRIRHPGGFHLINAAAERRWMTPSGKANFITSKGL
LEDPSSAFNSKLVMATVXSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAKICRVKNGEXVNLIALTPD
GKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHDPLSGIPGYKSIPVELEPSN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: z2207 mutant is attenuated in calves (van et al., 2005).
COG COG0243C, under C: Energy production and conversion
References
van et al., 2005: van Diemen PM, Dziva F, Stevens MP, Wallis TS. Identification of enterohemorrhagic Escherichia coli O26:H- genes required for intestinal colonization in calves. Infection and immunity. 2005; 73(3); 1735-1743. [PubMed: 15731074].