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narG

Victor ID 2180
Gene Name narG
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 960477
NCBI Protein GI 15801455
Locus Tag Z2001
Genbank Accession AE005174
Protein Accession NP_287472
Other Database IDs UniProtKB-ID: Q8XDC8_ECO57
UniRef100: UniRef100_C3TCS7
UniRef90: UniRef90_P09152
UniRef50: UniRef50_P09152
UniParc: UPI00000D0390
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG56084.1
EMBL-CDS: BAB35152.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
HSSP: P09152
EnsemblGenome: EBESCG00000025422.
EnsemblGenome_TRS: EBESCT00000026369
EnsemblGenome_PRO: EBESCP00000025262
EnsemblGenome: EBESCG00000056010.
EnsemblGenome_TRS: EBESCT00000056962
EnsemblGenome_PRO: EBESCP00000054790
GenomeReviews: AE005174
Taxonomy ID 155864
Gene Starting Position 1817022
Gene Ending Position 1820765
Gene Strand (Orientation) +
Protein Name nitrate reductase 1, alpha subunit
Protein pI 6.47
Protein Weight 133609.35
Protein Length 1247
DNA Sequence 
>gi|16445223:1817022-1820765 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
GATGAGTAAATTCCTGGACCGGTTTCGCTACTTCAAACAGAAGGGTGAAACCTTTGCCGATGGGCATGGC
CAGCTTCTCAATACCAACCGTGACTGGGAGGATGGATATCGCCAGCGTTGGCAGCATGACAAAATCGTCC
GCTCTACCCACGGGGTAAACTGCACCGGCTCCTGCAGCTGGAAAATCTACGTCAAAAACGGTCTGGTCAC
CTGGGAAACCCAGCAGACTGACTATCCGCGTACCCGTCCGGATCTGCCAAACCATGAACCTCGCGGCTGC
CCGCGCGGTGCCAGCTACTCCTGGTATCTTTACAGTGCCAACCGCCTGAAATACCCGATGATGCGCAAAC
GCCTGATGAAAATGTGGCGTGAAGCGAAGGCGCTGCATAGCGATCCGGTTGAGGCATGGGCTTCTATCAT
TGAAGACGCCGATAAAGCGAAAAGCTTTAAGCAGGCGCGTGGACGCGGTGGTTTTGTTCGTTCTTCCTGG
CAGGAGGTGAACGAACTGATCGCCGCATCTAACGTTTACACCATCAAAAACTACGGCCCGGACCGTGTTG
CTGGTTTCTCGCCAATTCCGGCAATGTCGATGGTTTCTTACGCATCGGGTGCACGCTATCTCTCGCTGAT
TGGCGGTACTTGCTTAAGCTTCTACGACTGGTACTGCGACCTGCCTCCTGCGTCTCCGCAAACCTGGGGC
GAGCAAACTGACGTACCGGAATCTGCTGACTGGTACAACTCCAGCTACATCATCGCCTGGGGTTCAAACG
TGCCGCAGACGCGTACCCCAGATGCTCACTTCTTTACTGAAGTGCGTTACAAAGGCACCAAAACTGTTGC
CGTCACACCAGACTACGCTGAAATCGCCAAACTGTGCGATCTGTGGCTGGCACCGAAACAGGGCACCGAT
GCGGCAATGGCGCTGGCGATGGGCCACGTAATGCTGCGTGAATTCCATCTCGACAACCCAAGCCAGTATT
TCACCGACTATGTGCGTCGCTACACCGACATGCCGATGCTGGTGATGCTGGAAGAACGCGACGGTTACTA
CGCTGCAGGTCGTATGCTGCGCGCTGCTGATCTGGTTGATGCGCTGGGCCAGGAAAACAATCCGGAATGG
AAAACTGTCGCCTTTAATACCAATGGCGAAATGGTTGCGCCGAACGGTTCTATTGGCTTCCGCTGGGGCG
AGAAGGGCAAATGGAATCTTGAGCAGCGCGACGGCAAAACTGGCGAAGAAACCGAGCTGCAACTGAGCCT
GCTGGGTAGCCAGGATGAGATCGCTGAGGTAGGCTTCCCGTACTTTGGTGGCGACGGCACGGAACACTTC
AACAAAGTGGAACTGGAAAACGTGCTGCTGCACAAACTGCCGGTGAAACGCCTGCAACTGGCTGATGGCA
GCACCGCCCTGGTGACCACCGTTTATGATCTGACGCTGGCAAACTACGGTCTGGAACGTGGCCTGAACGA
CGTTAACTGTGCAACCAGCTATGACGATGTGAAAGCTTATACCCCGGCCTGGGCCGAGCAGATTACCGGC
GTTTCTCGCAGCCAGATTATTCGCATCGCCCGTGAATTTGCCGATAACGCTGATAAAACGCACGGTCGTT
CGATGATTATCGTCGGTGCGGGGCTGAACCACTGGTATCACCTCGATATGAACTATCGTGGTCTGATCAA
CATGCTGATTTTCTGCGGCTGTGTCGGTCAGAGCGGGGGCGGCTGGGCGCACTATGTAGGTCAGGAAAAA
CTGCGTCCGCAAACCGGCTGGCAGCCGCTGGCGTTTGCCCTCGACTGGCAGCGTCCGGCGCGTCACATGA
ACAGCACTTCTTATTTCTATAACCACTCCAGCCAGTGGCGTTATGAAACCGTGACTGCGGAAGAACTGCT
GTCGCCGATGGCGGATAAATCCCGCTATACCGGACATCTGATCGACTTTAACGTCCGTGCAGAACGCATG
GGCTGGCTGCCGTCTGCGCCGCAGTTAGGCACTAACCCGCTGACTATCGCTGGCGAAGCAGAAAAAGCCG
GGATGAATCCGGTGGACTATACGGTGAAATCCCTGAAAGAGGGTTCTATCCGTTTCGCTGCGGAACAGCC
GGAAAACGGCAAAAACCACCCGCGTAACCTGTTTATCTGGCGTTCTAACCTGCTCGGTTCTTCCGGTAAA
GGTCATGAGTTTATGCTCAAGTACCTGCTGGGGACGGAGCACGGTATCCAGGGTAAAGATCTGGGGCAGC
AGGGCGGCGTGAAGCCGGAAGAAGTGGACTGGCAGGACAATGGTCTGGAAGGCAAGCTGGATCTGGTGGT
TACGCTGGACTTCCGTCTGTCGAGCACCTGTCTCTATTCCGACATCATTTTGCCGACGGCGACCTGGTAC
GAAAAAGACGACATGAATACTTCGGATATGCATCCGTTTATTCACCCGCTGTCTGCGGCGGTCGATCCGG
CCTGGGAAGCGAAAAGCGACTGGGAAATCTACAAAGCCATCGCGAAGAAATTCTCCGAAGTGTGCGTCGG
CCATCTGGGTAAAGAAACCGACATCGTCACGCTGCCTATCCAGCACGACTCTGCCGCTGAACTGGCGCAG
CCGCTGGATGTGAAAGACTGGAAAAAAGGCGAATGCGACCTGATCCCAGGCAAAACTGCACCGCACATTA
TGGTCGTAGAGCGCGATTATCCGGCAACTTACGAACGCTTTACCTCTATCGGCCCGCTGATGGAGAAAAT
CGGTAACGGCGGTAAAGGGATTGCCTGGAACACCCAGAGCGAGATGGATCTGCTGCGTAAGCTCAACTAC
ACCAAAGCGGAAGGTCCGGCGAAAGGCCAGCCGATGCTGAACACCGCAATTGATGCGGCAGAGATGATCC
TGACACTGGCACCGGAAACCAACGGTCAGGTAGCCGTGAAAGCCTGGGCTGCCCTGAGCGAATTTACCGG
TCGTGACCATACGCATCTGGCGCTGAATAAAGAAGACGAGAAGATCCGCTTCCGCGATATTCAGGCACAG
CCGCGCAAAATTATCTCCAGCCCGACCTGGTCTGGTCTGGAAGATGAACACGTTTCTTACAACGCCGGTT
ACACCAACGTTCACGAGCTGATCCCATGGCGTACGCTCTCTGGTCGTCAGCAACTGTATCAGGATCACCA
GTGGATGCGTGATTTCGGTGAAAGCCTGCTGGTTTATCGTCCGCCGATCGACACCCGTTCGGTGAAAGAA
GTGATAGGCCAGAAATCCAACGGCAACCCGGAAAAAGCGCTCAAYTTCCTGACGCCGCACCAGAAGTGGG
GTATCCACTCCACCTACAGCGACAACCTGCTGATGCTGACTTTAGGTCGCGGTGGTCCGGTGGTCTGGTT
GAGTGAAGCCGATGCCAAAGATCTGGGTATCGCCGATAACGACTGGATTGAAGTATTCAACAGCAACGGT
GCTCTGACTGCCCGTGCGGTTGTCAGCCAGCGTGTTCCGGCAGGGATGACCATGATGTACCACGCGCAGG
AACGTATCGTTAACCTGCCTGGTTCGGAAATTACCCAACAGCGTGGTGGTATCCATAACTCGGTCACCCG
TATCACGCCGAAACCGACGCATATGATCGGCGGCTATGCCCATCTGGCATACGGCTTTAACTACTACGGC
ACCGTAGGTTCTAACCGCGATGAGTTTGTTGTAGTGCGTAAGATGAAGAACATTGACTGGTTAGATGGCG
AAGGCAATGATCAGGTACAGGAGAGCGTAAAATG
Protein Sequence 
>gi|15801455|ref|NP_287472.1| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EDL933]
MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSWKIYVKNGLVT
WETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASII
EDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLI
GGTCLSFYDWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVA
VTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRYTDMPMLVMLEERDGYY
AAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIGFRWGEKGKWNLEQRDGKTGEETELQLSL
LGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLND
VNCATSYDDVKAYTPAWAEQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLIN
MLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELL
SPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEGSIRFAAEQP
ENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVV
TLDFRLSSTCLYSDIILPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVG
HLGKETDIVTLPIQHDSAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKI
GNGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAWAALSEFTG
RDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLSGRQQLYQDHQ
WMRDFGESLLVYRPPIDTRSVKEVIGQKSNGNPEKALNFLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWL
SEADAKDLGIADNDWIEVFNSNGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTR
ITPKPTHMIGGYAHLAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: narG mutant is attenuated in calves (van et al., 2005).
COG COG5013C, under C: Energy production and conversion
References
van et al., 2005: van Diemen PM, Dziva F, Stevens MP, Wallis TS. Identification of enterohemorrhagic Escherichia coli O26:H- genes required for intestinal colonization in calves. Infection and immunity. 2005; 73(3); 1735-1743. [PubMed: 15731074].