Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

dsbA from Escherichia coli O157:H7 str. EDL933

Victor ID 2177
Gene Name dsbA from Escherichia coli O157:H7 str. EDL933
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 960300
NCBI Protein GI 15804445
Locus Tag Z5392
Protein Accession NP_290485.1
Other Database IDs UniProtKB-ID: DSBA_ECO57
UniRef100: UniRef100_P0AEG5
UniRef90: UniRef90_P0A4L6
UniRef50: UniRef50_P0A4L6
UniParc: UPI000002D10B
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG59049.1
EMBL-CDS: BAB38206.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
MINT: MINT-1247926
EnsemblGenome: EBESCG00000026589
EnsemblGenome_TRS: EBESCT00000027537
EnsemblGenome_PRO: EBESCP00000026430
EnsemblGenome: EBESCG00000057283
EnsemblGenome_TRS: EBESCT00000058235
EnsemblGenome_PRO: EBESCP00000056063
GenomeReviews: AE0051
Taxonomy ID 155864
Gene Starting Position 4908133
Gene Ending Position 4908759
Gene Strand (Orientation) +
Protein Name periplasmic protein disulfide isomerase I
DNA Sequence 
>gi|16445223:4908133-4908759 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
CATGAAAAAGATTTGGCTGGCGCTGGCTGGTTTAGTTTTAGCGTTTAGCGCATCGGCGGCGCAGTATGAA
GATGGTAAACAGTACACTACCCTGGAAAAACCGGTAGCTGGCGCGCCGCAAGTGCTGGAGTTTTTCTCTT
TCTTCTGCCCGCACTGCTATCAGTTTGAAGAAGTTCTGCATATTTCTGATAATGTGAAGAAAAAACTGCC
GGAAGGCGTGAAGATGACTAAATACCACGTCAACTTCATGGGTGGTGACCTGGGCAAAGATCTGACTCAG
GCATGGGCTGTGGCGATGGCGCTGGGCGTGGAAGACAAAGTGACTGTTCCGCTGTTTGAAGGCGTACAGA
AAACCCAGACCATTCGTTCAGCATCTGATATCCGCGATGTATTTATCAACGCAGGTATTAAAGGTGAAGA
GTACGACGCGGCGTGGAACAGCTTCGTGGTGAAATCTCTGGTCGCTCAGCAGGAAAAAGCTGCAGCTGAC
GTGCAATTGCGTGGTGTTCCGGCGATGTTTGTTAACGGTAAATATCAGCTGAATCCGCAGGGTATGGATA
CCAGCAATATGGATGTTTTTGTTCAGCAGTATGCTGATACAGTGAAATATCTGTCCGAGAAAAAATA
Protein Sequence 
>gi|15804445|ref|NP_290485.1| protein disulfide isomerase [Escherichia coli O157:H7 str. EDL933] MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutation of dsbA led to degradation of bundilin and an absence of localized adherence to host cells in EPEC (Donnenberg et al., 1997).
COG COG1651O, under O: Posttranslational modification, protein turnover, chaperones
References
Donnenberg et al., 1997: Donnenberg MS, Zhang HZ, Stone KD. Biogenesis of the bundle-forming pilus of enteropathogenic Escherichia coli: reconstitution of fimbriae in recombinant E. coli and role of DsbA in pilin stability--a review. Gene. 1997; 192(1); 33-38. [PubMed: 9224871].