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agaB

Victor ID 2161
Gene Name agaB
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 959220
NCBI Protein GI 15803678
Locus Tag Z4492
Genbank Accession AE005174
Protein Accession NP_289711
Other Database IDs UniProtKB-ID: Q8XAB8_ECO57
UniRef100: UniRef100_C3ST27
UniRef90: UniRef90_P42909
UniRef50: UniRef50_P42909
UniParc: UPI00000D0713
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG58270.1
EMBL-CDS: BAB37441.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
PDB: 3EYE
EnsemblGenome: EBESCG00000024687.
EnsemblGenome_TRS: EBESCT00000025634
EnsemblGenome_PRO: EBESCP00000024527
EnsemblGenome: EBESCG00000056984.
EnsemblGenome_TRS: EBESCT00000057936
EnsemblGenome_PRO: EBESCP00000055764
GenomeReviews: AE005174_GR
Taxonomy ID 155864
Gene Starting Position 4092925
Gene Ending Position 4093401
Gene Strand (Orientation) +
Protein Name PTS system N-acetylgalactosamine-specific transporter subunit IIB
Protein pI 6.8
Protein Weight 15822.83
Protein Length 158
Protein Note catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport
DNA Sequence 
>gi|16445223:4092925-4093401 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
AATGAGCAGTCCAAATATTCTCTTAACCCGTATTGATAACCGTCTGGTTCACGGTCAGGTTGGCGTGACC
TGGACATCCACCATCGGTGCGAATCTGCTGGTAGTCGTGGATGATGTTGTCGCTAACGATGATATTCAAC
AGAAATTAATGGGTATTACCGCAGAAACCTACGGCTTTGGCATTCGTTTCTTTACTATCGAAAAAACCAT
TAACGTCATCGGCAAAGCTGCACCGCATCAGAAGATCTTCCTGATTTGCCGTACGCCACAAACGGTACGT
AAATTGGTAGAAGGTGGCATTGACCTGAAAGATGTCAACGTCGGCAATATGCATTTCTCGGAAGGGAAAA
AGCAAATCAGCAGTAAAGTTTATGTCGATGACCAGGATCTCACGGACTTACGTTTTATTAAACAACGTGG
CGTGAATGTTTTCATTCAGGACGTCCCTGGCGATCAAAAAGAACAAATCCCTGACTA
Protein Sequence 
>gi|15803678|ref|NP_289711.1| PTS system N-acetylgalactosamine-specific transporter subunit IIB [Escherichia coli O157:H7 str. EDL933]
MSSPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDDIQQKLMGITAETYGFGIRFFTIEKTI
NVIGKAAPHQKIFLICRTPQTVRKLVEGGIDLKDVNVGNMHFSEGKKQISSKVYVDDQDLTDLRFIKQRG
VNVFIQDVPGDQKEQIPD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: agaB mutant is attenuated in calves (Dziva et al., 2004).
COG COG3444G, under G: Carbohydrate transport and metabolism
References
Dziva et al., 2004: Dziva F, van Diemen PM, Stevens MP, Smith AJ, Wallis TS. Identification of Escherichia coli O157 : H7 genes influencing colonization of the bovine gastrointestinal tract using signature-tagged mutagenesis. Microbiology (Reading, England). 2004; 150(Pt 11); 3631-3645. [PubMed: 15528651].