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ompA from Escherichia coli O157:H7 str. EDL933

Victor ID 2155
Gene Name ompA from Escherichia coli O157:H7 str. EDL933
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 958948
NCBI Protein GI 15800816
Locus Tag Z1307
Protein Accession NP_286832.1
Other Database IDs UniProtKB-ID: OMPA_ECO57
UniRef100: UniRef100_P0A911
UniRef90: UniRef90_B7LNW7
UniRef50: UniRef50_B7LNW7
UniParc: UPI0000130CF0
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG55443.1
EMBL-CDS: BAB34464.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000025749
EnsemblGenome_TRS: EBESCT00000026696
EnsemblGenome_PRO: EBESCP00000025589
EnsemblGenome: EBESCG00000055744
EnsemblGenome_TRS: EBESCT00000056696
EnsemblGenome_PRO: EBESCP00000054524
GenomeReviews: AE005174_GR
GenomeReviews
Taxonomy ID 155864
Gene Starting Position 1237706
Gene Ending Position 1238746
Gene Strand (Orientation) -
Protein Name outer membrane protein A
DNA Sequence 
>gi|16445223:1237706-1238746 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
CTTAAGCTTGCGGCTGAGTTACAACGTCTTTGATACCTTTAACTTCGATCTCTACGCGACGATCCGGAGC
CAGGCAGTCGATCAGTGCAGCACGCTGTTTCACGTTGTCACAGGTGTTGCCAGTAACCGGGTTGGATTCG
CCCATACCACGTGCGGAGATCTTGTCTGCCGGGATACCTTTGGAGATCAGGTAATCAACAACAGACTGAG
CACGGCGCTCGGACAGACCCTGGTTGTAAGCGTCAGAACCGATGCGGTCGGTGTAACCCAGAACAACTAC
GGAACCGTCTTTCGGATCCAGGTTGCTCAGCTGGCTGTACAGCTGATCCAGAGCAGCCTGACCTTCCGGT
TTCAGGGTTGCTTTGTTGAAGTTGAACAGAACGTCAGACTTCAGAGTGAAGTGCTTGGTCTGTACTTCCG
GTGCCGGAGCTGGAGCCGGAGCAACTACTGGAGCTGCTTCGCCCTGACCGAAACGGTAGGAAACACCCAG
GCTCAGCATGCCGTTGTCCGGACGAGTGCCGATGGTGTGTGCGTCACCGATGTTGTTGGTCCACTGGTAT
TCCAGACGGGTAGCGATTTCAGGAGTGATCGCGTACTCAACACCGCCAGCGAAGACCGGAGAAACGCCGG
TGTCGTGGTTTTTACCATAAACGTTGGATTTAGTGTCTGCACGCCATACCATACCACCCAGACGAGTGTA
GATGTCCAGGTCGTCAGTGATTGGGTAACCCAGTTTAGCGGTCAGTTGAACGCCCTGAGCTTTGTATGCA
CCGTTTTCAACGCTGCCTTTGTACGGCATACGACCTAACCAGTCGTAACCCATTTCAAAGCCAACATACG
GGTTAACCTGGTAACCACCAAAAGCACCAGCGCCCAGTTGGTTTTCATGGGTCGGGCCATTGTTGTTGAT
GAAACCAGTGTCATGGTACTGGGACCAGCCCAGTTTAGCACCAGTGTACCAGGTGTTATCTTTCGGAGCG
GCCTGCGCTACGGTAGCGAAACCAGCCAGTGCCACTGCAATCGCGATAGCTGTCTTTTTCA
Protein Sequence 
>gi|15800816|ref|NP_286832.1| outer membrane protein OmpA [Escherichia coli O157:H7 str. EDL933] MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: OmpA− strains are unable to cause actin condensation needed for invasion of brain epithelial cells (Prasadarao et al., 1999).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Prasadarao et al., 1999: Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS. Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infection and immunity. 1999; 67(11); 5775-5783. [PubMed: 10531228].