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trxB

Victor ID 2154
Gene Name trxB
Sequence Strain (Species/Organism) Escherichia coli
NCBI Gene ID 958846
NCBI Protein GI 15800751
Locus Tag Z1232
Protein Accession NP_286765.1
Other Database IDs UniProtKB-ID: TRXB_ECO57
UniRef100: UniRef100_P0A9P5
UniRef90: UniRef90_P0A9P5
UniRef50: UniRef50_Q89AJ2
UniParc: UPI00001653E0
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG55375.1
EMBL-CDS: BAB34396.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000027312
EnsemblGenome_TRS: EBESCT00000028261
EnsemblGenome_PRO: EBESCP00000027154
EnsemblGenome: EBESCG00000058751
EnsemblGenome_TRS: EBESCT00000059704
EnsemblGenome_PRO: EBESCP00000057532
GenomeReviews: AE005174_GR
GenomeReviews
Taxonomy ID 155864
Gene Starting Position 1151384
Gene Ending Position 1152349
Gene Strand (Orientation) -
Protein Name thioredoxin reductase
DNA Sequence 
>gi|16445223:1151384-1152349 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
ATTATTTTGCGTCAGCTAAACCATCGAGGTAGCGTTCCGCATCAAGTGCTGCCATGCAGCCTGTACCAGC
AGATGTAATGGCCTGGCGATAAATGTGATCCATCACGTCGCCTGCGGCAAAGACGCCAGGAATGCTGGTC
TGGGTGGCATTACCATGAATACCCGACTGCACTTTGATGTAGCCGTTTTCCAGTTCCAGCTGCCCTTCGA
AAATGGCAGTATTCGGGCTGTGACCGATAGCAACAAACAGACCGGCAACGTCGAGTGACTCGATGTTATC
GCTGTTTTGCGTATCGCGCAGACGAACGCCAGTGACACCCATTTGATCGCCGGTCACTTCTTCCAGCGTA
CGGTTGGTGTGCAGAATGATGTTGCCGTTCTCCACTTTATCCATCAGACGCTTAATGAGGATTTTTTCCG
CGCGGAAACCGTCACGGCGGTGAATCAGATGCACTTCCGAAGCGATGTTAGACAGATACAGCGCCTCTTC
AACCGCGGTATTGCCGCCGCCGATGACCGCAACTTTCTGGTTGCGATAGAAGAAACCGTCGCAGGTTGCA
CAAGCAGAAACTCCACGGCCTTTAAAGGCTTCTTCAGAGGGCAGGCCGAGATAGCGTGCAGAAGCTCCGG
TGGCAATAATCAGCGCGTCGCAAGTGTATTCGCCGTTATCGCCATTCAGACGGAACGGACGGTTTTGCAG
ATCCACCTTGTTGATATGATCAAAAATGATCTCAGTTTCAAACTTGGTGGCATGTTCGTGCATGCGCTCC
ATTAATAACGGACCGGTCAGATCGTTTGGATCGCCAGGCCAGTTTTCCACTTCCGTGGTGGTGGTCAGTT
GGCCGCCTTTTTCCATGCCGGTAATCAGCACAGGTTGCAGGTTGGCGCGCGCCGCATAGACAGCAGCGGT
GTATCCCGCCGGGCCTGAACCCAGGATAAGCAGTTTACTGTGTTTGGTCGTGCCCA
Protein Sequence 
>gi|15800751|ref|NP_286765.1| thioredoxin reductase [Escherichia coli O157:H7 str. EDL933] MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trxB mutant is attenuated in calves (van et al., 2005).
COG COG0492O, under O: Posttranslational modification, protein turnover, chaperones
References
van et al., 2005: van Diemen PM, Dziva F, Stevens MP, Wallis TS. Identification of enterohemorrhagic Escherichia coli O26:H- genes required for intestinal colonization in calves. Infection and immunity. 2005; 73(3); 1735-1743. [PubMed: 15731074].