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speA

Victor ID 2146
Gene Name speA
Sequence Strain (Species/Organism) Escherichia coli
NCBI Gene ID 958416
NCBI Protein GI 15803477
Locus Tag Z4283
Protein Accession NP_289510.1
Other Database IDs UniProtKB-ID: SPEA_ECO57
UniRef100: UniRef100_B5YQD6
UniRef90: UniRef90_B5YQD6
UniRef50: UniRef50_Q0T0V3
UniParc: UPI00000D040C
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG58069.1
EMBL-CDS: BAB37237.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000023198
EnsemblGenome_TRS: EBESCT00000024144
EnsemblGenome_PRO: EBESCP00000023037
EnsemblGenome: EBESCG00000058408
EnsemblGenome_TRS: EBESCT00000059361
EnsemblGenome_PRO: EBESCP00000057189
GenomeReviews: AE005174_GR
GenomeReviews
Taxonomy ID 155864
Gene Starting Position 3892728
Gene Ending Position 3894704
Gene Strand (Orientation) -
Protein Name arginine decarboxylase
DNA Sequence 
>gi|16445223:3892728-3894704 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
ATTATTCATCTTCAAGATAGGTATAACCGTACAAACCTGCCTCGAACTCTTCAAGGAACTGTTGTTGCAG
TTCAGCATCAAGATCGGTTTTCTTCACTTGATCACGGAACTGAGTTAACAGCGTTTTCGGATCGAGCTGT
ACATATTGCAGCATGTCCGCCACGGTATCGCCTTCGTCAGACAGTTCCACTTCTACACTACCGTCAGGGA
AGACGAACACGTCAACCGCTTCGGTATCACCGAACAGGTTGTGCATGTTGCCGAGGATCTCCTGATATGC
GCCGACCATAAAGAAACCGAGCATCGGCGGATTCTCTGGATCGTACTCCGGCATAGGCATTGTCGTGGCA
ATACCATCACCATCGATATAGTGGTCGATAGCACCGTCAGAGTCACAGGTAATATCCAGCAGCACAGCGC
GGCGTTCCGGCACTTGATCCAGCCCTTCCAGCGGCAGAACCGGGAACAACTGGTCGATCCCCCACGCATC
CGGCATCGACTGGAACAGCGAGAAGTTGACGTACATTTTGTCCGCCATACGTTCCTGCAGCTCGTCGATA
ATCGGACGATGAGCACGGTTTTGCGGATCCAGCTGCTTTTGCACTTCATGGCACATGCTCAAATAAAGCT
GCTCAGCCCATGCACGTTCTTGCAGGCTAAAGGTGCCGGAAGAGTAGCCGATATGAATGTCGTGCAGATC
CATCTGACTGTCGTGTAACCATTCACGCAGAGAACGGCGAGTTCCCGGTTCGTGCATCTCCTGCCAGGTT
TCCCACATGCTTTGCAGCGCGCGCGGCGCATCTTCTGCAGGCGCGGTCGGCACCGTGTATTCGTTACGTT
CCACGCCGATGATATTAGACACCAGCACGGTGTGATGCGCAGTCACTGCACGACCCGATTCGGTGATTAC
CGTCGGATGCGGCAGACCGTTTTCTTCACACGCATCACCAATCGCCCAGATGATGTTGTTGGCATATTCA
TTGAGGCCGTAGTTCACCGAACAGTCGGACTGCGAACGAGTACCTTCATAATCCACGCCCAGACCGCCGC
CGACGTCGAAGCACTGAATATTGACGCCCAGCTTGTGCAGCTCAACATAGAAACGCGCGGATTCACGAAC
GCCTGTCGCGATATCGCGAATATTCGCCATCTGCGAACCGAGGTGGAAGTGCAGTAGTTGCAGGCTGTCG
AGACGCCCGGCTTCACGTAGGGTTTCAACCAGTTGCAGTACCTGAGTCGCCGCCAGGCCGAACTTCGATT
TTTCCCCGCCGGAGGACTGCCATTTACCGGAGCCCTGCGAAGCCAGACGTGCACGCACGCCCAGACGAGG
AACGACATTCAGACGTTCTGCTTCATCCAGCACAATGGCGATTTCTGACATCTTCTCAATGACCAGATAG
ACCTTGTGCCCCATCTTCTCGCCAATTAATGCCAGGCGGATATATTCGCGGTCTTTATAACCATTGCAGA
CGATGACGCTACGGGTCATGCCAGCATGTGCCAGCACTGCCATCAACTCGGCTTTGGAACCGGCTTCCAG
ACCCAGCGGTTCGCCCGAATGAATCAGGGACTCAATCACGCGACGGTGCTGGTTAACTTTGATCGGATAA
ACAAGGAAGTAATCGCCGTTATAGCCGTAGGATTCCCGCGCACGTTTGAACGCGGCGTTAATGGAACGCA
AACGGTGCTGCAGGATCTGTGGGAAACAGAACAGTGCAGGCAGACGCTGACCCTGTGCTTCACGAGTTTT
CACTAACTGCGCGAGATCGACGCGAGCTTCCGGGACGTCCGGGTCCGGGCACACGCTGATGTGGCCCAGC
TCGTTAACGTCATAGTAGTTATTGCCCCACCAGGCAATATTGTAAGTACGCAGCATCTTGCTGGCTTCCT
GGGAGCTCATTGCAACCTCCTGCATGGAGCGTAGTACACCGTGTTCGCCCGCTGACGAAGGCAAACCCAT
AGACATGTCGTCAGACA
Protein Sequence 
>gi|15803477|ref|NP_289510.1| arginine decarboxylase [Escherichia coli O157:H7 str. EDL933] MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAEDAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGTFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQFRDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: speA mutant is attenuated in calves (van et al., 2005).
COG COG1166E, under E: Amino acid transport and metabolism
References
van et al., 2005: van Diemen PM, Dziva F, Stevens MP, Wallis TS. Identification of enterohemorrhagic Escherichia coli O26:H- genes required for intestinal colonization in calves. Infection and immunity. 2005; 73(3); 1735-1743. [PubMed: 15731074].