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evgS

Victor ID 2136
Gene Name evgS
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 957555
NCBI Protein GI 15802913
Locus Tag Z3632
Genbank Accession AE005174
Protein Accession NP_288940
Other Database IDs UniProtKB-ID: EVGS_ECO57
UniRef100: UniRef100_P58402
UniRef90: UniRef90_P58402
UniRef50: UniRef50_P58402
UniParc: UPI000012A2A7
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG57495.1
EMBL-CDS: BAB36672.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000026286
EnsemblGenome_TRS: EBESCT00000027234
EnsemblGenome_PRO: EBESCP00000026127
EnsemblGenome: EBESCG00000057446
EnsemblGenome_TRS: EBESCT00000058398
EnsemblGenome_PRO: EBESCP00000056226
GenomeReviews: AE005174_GR
GenomeReviews
Taxonomy ID 155864
Gene Starting Position 3282469
Gene Ending Position 3286062
Gene Strand (Orientation) +
Protein Name hybrid sensory histidine kinase in two-component regulatory system with EvgA
Protein pI 6.09
Protein Weight 127906.47
Protein Length 1197
DNA Sequence 
>gi|16445223:3282469-3286062 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
CATGAAGTTTTTACCCTATATTTTTCTTCTCTGTTGTGGTCTTTGGTCGACCATAAGTTTCGCAGACGAA
GATTACATCGAATATCGTGGCATCAGTAGTAACAACCGTGTCACACTTGATCCACTACGTCTGAGCAACA
AGGAATTACGTTGGTTAGCGAGCAAAAAAAATCTTGTGATTGCAGTACACAAGTCCCAAACGGCTACGTT
GTTGCATACCGATTCGCAGCAACGGGTTCGTGGTATTAATGCTGATTATTTAAATCTTTTAAAAAGAGCG
TTAAATATCAAATTAACACTCCGGGAATACGCAGATCATCAAAAAGCAATGGACGCGCTGGAAGAAGGTG
AAGTCGATATAGTGTTATCACATTTAGTTGCTTCGCCGCCTCTTAATGATGACATTGCTGCAACCAAACC
ACTGATAATTACCTTTCCGGCGCTGGTCACCACCCTTCACGATTCAATGCGACCGCTTACYTCATCAAAA
CCAGTAAATATTGCTCGAGTAGCAAATTATCCCCCTGACGAGGTAATTCATCAATCATTTCCAAAAGCAA
CAATTATCTCTTTTACAAATTTATATCAGGCATTAGCATCCGTCTCAGCCGGACAGAATGATTACTTTAT
TGGTAGTAACATCATTACCAGCAGTATGATTTCCCGCTATTTCACTCACTCCTTAAATGTAGTGAAATAT
TATAACTCACCGCGTCAATATAACTTCTTCTTAACCAGAAAAGAATCTGTCATTCTTAATGAAGTACTCA
ATCGATTTGTTGATGCTTTAACAAATGAAGTTCGCTATGAAGTATCACAAAATTGGCTTGATACAGGAAA
CCTGGCCTTTCTGAACAAGCCATTAGAACTCACTGAACATGAAAAACAGTGGATTAAGCAGCATCCCGAT
TTAAAGGTGCTGGAAAATCCTTACTCGCCCCCCTATTCTATGACGGATGAAAATGGCTCGGTTCGGGGCG
TTATGGGGGACATTCTTAATATTATTACCTTGCAAACAGGTTTAAATTTTTCTCCGATCACCGTTTCACA
CAATATCCATGCTGGAACACAGCTGAATCCCGGCGGATGGGATATATTACCCGGTGCTATTTATAGTGAA
GATAGAGAAAATAATGTTTTATTTGCTGAAGCCTTCATAACAACGCCTTACGTTTTTGTCATGCAAAAAG
CGCCTGACAGTGAACAAACATTAAAAAAAGGAATGAAAGTTGCCATTCCATATTATTATGAGCTTCATTC
GCAATTAAAAGAGATGTATCCGGAGGTAGAGTGGATAAAAGTCGATAACGCCAGCGCTGCATTTCACAAG
GTCAAGGAAGGCGAACTTGATGCTCTGGTCGCGACACAGTTAAATTCACGTTACATGATCGACCATTACT
ATCCTAATGAACTGTATCATTTTCTTATTCCCGGCGTTCCGAATGCATCGCTTTCGTTCGCTTTTCCTCG
CGGAGAACCGGAACTTAAGGATATTATTAATAAAGCACTGAATGCAATCCCCCCAAGCGAAGTTCTGCGC
CTGACCGAAAAATGGATTAAAATGCCCAATGTGACCATTGACACATGGGACCTCTATAGCGAGCAATTTT
ATATTGTTACGACATTATCCGTTTTATTAGTTGGCAGTAGCCTTTTATGGGGATTCTACCTGTTACGCTC
AGTTCGTCGTCGTAAAGTCATTCAGGGTGATTTAGAAAACCAAATATCATTCCGGAAAGCGCTCTCGGAC
TCCTTACCGAATCCAACTTATGTTGTAAACTGGCAAGGTAATGTCATTAGTCACAATAGTGCATTTGAAC
ATTATTTCACTGCTGATTACTACAAAAATGCAATGTTGCCATTAGAAAACAGTGAATCACCCTTTAAAGA
TGTTTTTTCTAATACGCATGAAGTCACAGCAGAGACGAAAGAAAACCGAACAATATACACACAGGTATTT
GAAATTGATAATGGCATCGAGAAAAGATGCATTAATCACTGGCATACATTATGTAATCTGCCAGCCAGCG
AACATGCTGTTTATATTTGTGGTTGGCAAGATATTACCGAGACGCGTGATTTAATTCATGCACTCGAAGT
AGAGAGAAATAAAGCGATCAATGCAACTGTCGCAAAAAGTCAGTTTCTGGCAACAATGAGTCACGAAATA
AGAACACCAATAAGCTCCATTATGGGCTTCCTGGAACTTCTGTCGGGTTCTGGTCTTAGCAAGGAGCAAC
GGGTGGAGGCGATTTCACTAGCCTACGCCACCGGACAATCACTCCTCGGCTTAATTGGTGAAATCCTTGA
TGTCGACAAAATTGAATCGGGTAACTATCAACTTCAACCACAATGGGTCGATATCCCTACTTTAGTCCAG
AACACTTGTCACTCTTTCGGTGCGATTGCTGCAAGCAAATCGATCGCATTAAGTTGCAGCAGTACATTTC
CTGATCATTACCTGGTTAAGATCGACCCTCAGGCGTTTAAGCAGGTCTTATCAAATTTACTGAGTAATGC
TCTCAAATTTACCACCGAGGGGGCAGTAAAAATTACGACCTCCCTGGTTCACATTGATGACAACCACGCT
GTAATCAAAATGACGATTATGGATTCTGGAAGTGGATTATCACAGGAAGAACAACAACAACTGTTTAAAC
GTTATAGCCAAACAAGTGCAGGTCGTCAGCAAACAGGTTCTGGTTTAGGCTTAATGATCTGCAAAGAATT
AATTAAAAACATGCAGGGTGATTTGTCATTAGAAAGTCATCCAGGCATAGGAACAACATTTACGATCACA
ATCCCGGTAGAAATTATCCAACAAGTGGCGGCTGTCGAGGCAAAAGCAGAACAACCCATCACACTACCTG
AAAAGTTGAGCATATTAATCGCGGATGATCATCCGACCAACAGGCTATTACTCAAACGCCAGCTAAATCT
ATTAGGATATGATGTTGATGAAGCCACTGATGGTGTGCAAGCGCTACACAAAGTCAGTATGCAACATTAT
GATCTGCTTATTACTGACGTTAATATGCCGAATGTGGATGGTTTTGAGTTGACTCGCAAACTCCGTGAGC
AAAATTCGTCCTTACCCATCTGGGGGCTTACAGCCAACGCACAGGCTAACGAACGTGAAAAAGGGTTAAA
TTGCGGCATGAACTTATGTTTGTTCAAACCGTTGACCCTGGATGTACTGAAAACACATTTAAGTCAGTTA
CACCAGGTTGCGCATATTGTACCTCAGTATCGCCACCTTGATATCGAGGCCCTGAAAAATAATACGGCGA
ACGATCTACAACTGATGCAGGAGATTCTCATGACTTTCCAGCATGAAACACATAAAGATTTACCCGCTGC
GTTTCATGCACTAGAAGCTGGCGATAATAGAACTTTCCATCAGTGTATTCATCGCATCCACGGTGCGGCT
AACATCCTGAATTTGCAAAAGTTGATTAATATTAGCCATCAGTTAGAAATAACACCTGTTTCAGATGACA
GTAAGCCTGAAATTCTTCAGTTGCTAAACTCTGTAAAAGAACACATTGCAGAGCTAGACCAGGAAATTGC
TGTTTTCTGTCAACAAAATAACTA
Protein Sequence 
>gi|15802913|ref|NP_288940.1| hybrid sensory histidine kinase in two-component regulatory system with EvgA [Escherichia coli O157:H7 str. EDL933]
MKFLPYIFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPLRLSNKELRWLASKKNLVIAVHKSQTATL
LHTDSQQRVRGINADYLNLLKRALNIKLTLREYADHQKAMDALEEGEVDIVLSHLVASPPLNDDIAATKP
LIITFPALVTTLHDSMRPLTSSKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGQNDYFI
GSNIITSSMISRYFTHSLNVVKYYNSPRQYNFFLTRKESVILNEVLNRFVDALTNEVRYEVSQNWLDTGN
LAFLNKPLELTEHEKQWIKQHPDLKVLENPYSPPYSMTDENGSVRGVMGDILNIITLQTGLNFSPITVSH
NIHAGTQLNPGGWDILPGAIYSEDRENNVLFAEAFITTPYVFVMQKAPDSEQTLKKGMKVAIPYYYELHS
QLKEMYPEVEWIKVDNASAAFHKVKEGELDALVATQLNSRYMIDHYYPNELYHFLIPGVPNASLSFAFPR
GEPELKDIINKALNAIPPSEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRS
VRRRKVIQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENSESPFKD
VFSNTHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASEHAVYICGWQDITETRDLIHALEV
ERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILD
VDKIESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTFPDHYLVKIDPQAFKQVLSNLLSNA
LKFTTEGAVKITTSLVHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKEL
IKNMQGDLSLESHPGIGTTFTITIPVEIIQQVAAVEAKAEQPITLPEKLSILIADDHPTNRLLLKRQLNL
LGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNVDGFELTRKLREQNSSLPIWGLTANAQANEREKGLN
CGMNLCLFKPLTLDVLKTHLSQLHQVAHIVPQYRHLDIEALKNNTANDLQLMQEILMTFQHETHKDLPAA
FHALEAGDNRTFHQCIHRIHGAANILNLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIA
VFCQQNN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: evgS mutant is attenuated in calves (van et al., 2005).
COG COG0642T, under T: Signal transduction mechanisms
References
van et al., 2005: van Diemen PM, Dziva F, Stevens MP, Wallis TS. Identification of enterohemorrhagic Escherichia coli O26:H- genes required for intestinal colonization in calves. Infection and immunity. 2005; 73(3); 1735-1743. [PubMed: 15731074].