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Z0469

Victor ID 2133
Gene Name Z0469
Sequence Strain (Species/Organism) Escherichia coli
NCBI Gene ID 957315
NCBI Protein GI 15800100
Locus Tag Z0469
Protein Accession NP_286112.1
Other Database IDs UniProtKB-ID: Q8X5H7_ECO57
UniRef100: UniRef100_Q8X5H7
UniRef90: UniRef90_D7YI74
UniRef50: UniRef50_P77199
UniParc: UPI00001656DA
EMBL: AE005174
EMBL-CDS: AAG54720.1
RefSeq_NT: NC_002655.2
EnsemblGenome: EBESCG00000026769.
EnsemblGenome_TRS: EBESCT00000027717
EnsemblGenome_PRO: EBESCP00000026610
GenomeReviews: AE005174_GR
KEGG: ece:Z0469
HOGENOM: HBG469899
OMA: GSEWDTT
ProtClustDB: CLSK2300837
Taxonomy ID 155864
Gene Starting Position 451256
Gene Ending Position 454198
Gene Strand (Orientation) +
Protein Name putative structural protein (partial)
DNA Sequence 
>gi|16445223:451256-454198 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
AATGCACTCCTGGAAAAAGAAACTTATAGTATCACAATTAGCATTGGCTTGCACTCTGGCTATCACCTCT
CAGGCTAATGCAGCGACCAATGATATTTCTGGTCAAACTTACAATACTTTCCATCACTACAACGACGCCA
CCTATGCTGATGACGTTTACTATGATGGTTATGTAGGCTGGAACAACTATGCCGCTGATAGCTATTACAA
CGGCGATATCTACCCGGTCATTAATAACGCTACCGTTAACGGCGTGATTTCTACCTACTATCTGGACGAC
GGTATTTCTACCAATACCAACGCCAATAGTCTGACAATCAAAAACAGCACTATTCACGGTATGATTACCT
CTGAGTGCATGACTACTGATTGTGCTGATGACCGTGCTACTGGTTATGTTTATGATCGTCTGACACTGAG
CGTTGATAATTCAACGATCGATGACAACTACGAGCATTATACTTACAACGGTACCTATAATAATGCCGCT
GACACTCATGTTGTAGATGTTTACGATATGGGTACTGCTATTACACTGGATCAGGAAGTTGATCTGTCCA
TCACTAATAACTCTCATGTAGCAGGTATTACGCTGACTCAGGGTTATGAGTGGGAAGATATTGACGACAA
CACAGTCAGCACTGGCGTAAACAGCAGCGAAGTGTTTAATAACACTATTACTGTTAAAGATTCTACTGTG
ACCTCTGGTTCATGGACTGATGAAGGTACTACTGGTTGGTTTGGCCATACTGGTAATGCCAGCAACTATA
GCAACACGCTGACTGCAGACGATGTTGCAATTGCCGCAATCGCAAATCCGTATGCTGATAATGCGATGCA
GACTACAGTAACTTTAGACAACTCAACACTGATGGGTGATGTTGTTTTCTCCAGTAATTTCGATGAAAAC
TTCTTCCCGCAAGGTGCTAACAGCTATCGCGATGCTGATGGTGATGTAGATACCAACGGTTGGGATGGCA
CAGACCGTATGGATGTGACTCTGAACAACGGCAGCAAGTGGGTTGGCGCTGCAATGTCTGTTCATATGGT
TGATGAAGATGGTGATGGTTCTTACGACGGATATGCTGTTGGTACTGAAGCAACTGCAACTCTGCTCGAT
ATTGCAGCTAACAGCCTGTGGCCTTCATCAACTGTCGGTGTTGATAACATCAATACTCAATATGACGAAA
ATGGCCATATCGTAGGAAACGAAGTTTACCAGAGCGGTTTGTTTAATGTGACTTTGAACGGTGGTTCAGA
GTGGGATACAACAAAATCTTCTCTGATTGATACTTTAAGTATTAACAGCGGTTCCCAAGTTAATGTTGCA
GACTCTCGTCTGATCTCTGACACTGTCTCTCTGACTGGCGGTTCTAACCTGAACATCGGTGAAGACGGTC
ATGTAGCGACTAATACCCTGACCATCGACAATAGTACCGTTAAAATGTCTGATGATGTTTCTGCGGGCTG
GGGTTTAGAAGATGCTGCACTGTACGCAAATACCATCACCGTAACTAACGACGGTCTGTTGGATATTAAC
GTTGATCAGTTCGATGCTAACCCGTTCCAGGCCGATACCCTGAATCTGACCAGTACCACTGATACTAACG
GCAACATTCACGCTGGTGTATTCGATATCCATAGCAGTGATTACGTAATGGATACCGATCTGGTCAACGA
TCGTACCAACGATACTACCAAGTCAAACTACGGTTATGGCTTAATCGCAATGAACTCTGATGGTCACCTG
ACTATTAACGGTAACGGCGATAACGACAACACTGCTTCTATCGAAGCTGGTCAGAACGAAGTTGATAACA
ACGGTGACCATGTTGCAGCCGCGACCGGTAACTACAAAGTTCGTATCGACAACGCTACTGGTGCTGGTTC
TATCGCTGACTACAACGGCAACGAGCTGATCTACGTCAACGACAAAAACAGCAACGCGACCTTCTCTGCT
GCTAACAAAGCTGACCTGGGTGCATACACCTATCAGGCTGAACAGCGCGGTAACACCGTTGTTCTGCAAC
AGATGGAGTTGACCGACTACGCTAACATGGCGCTGAGCATCCCATCTGCGAACACCAATATCTGGAACCT
GGAACAAGACACCGTTGGTACTCGTTTGACCAACTCTCGTCATGGCCTGGCTGATAACGGCGGCGCATGG
GTAAGCTACTTCGGTGGTAACTTCAACGGCGACAACGGCACCATCAACTATGATCAGGATGTTAACGGCA
TCATGGTCGGTGTTGATACCAAAATTGACGGTAACAACGCTAAGTGGATCGTCGGTGCGGCTGCAGGCTT
CGCTAAAGGTGACATGAATGACCGTTCTGGTCAGGTGGATCAAGACAGCCAGACTGCCTACATCTACTCT
TCTGCTCACTTCGCGAACAACGTCTTTGTTGATGGTAGCTTGAGCTACTCTCACTTCAACAACGACCTGT
CTGCAACCATGAGCAACGGTACTTACGTTGACGGTAGCACCAACTCCGACGCTTGGGGCTTCGGTTTGAA
AGCCGGTTACGACTTCAAACTGGGTGATGCTGGTTACGTGACTCCTTACGSCAGCATTTCTGGTCTGTTC
CAGTCTGGTGATGACTACCAGCTGAGCAACGACATGAAAGTTGACGGTCAGTCTTACGACAGCATGCGTT
ATGAACTGGGTGTAGATGCAGGTTATACCTTCACCTACAGCGAAGATCAGGCTCTGACTCCGTACTTCAA
ACTGGCTTACGTCTACGACGACTCTAACAACGATAACGATGTGAACGGTGATTCCATCGATAACGGTACT
GAAGGGTCTGCGGTACGTGTTGGTCTGGGTACTCAGTTCAGCTTCACCAAGAACTTCAGCGCCTATACCG
ATGCTAACTACCTCGGTGGTGGTGACGTAGATCAAGACTGGTCCGCGAACGTGGGTGTTAAATATACCTG
GTA
Protein Sequence 
>gi|15800100|ref|NP_286112.1| hypothetical protein Z0469 [Escherichia coli O157:H7 str. EDL933] MHSWKKKLIVSQLALACTLAITSQANAATNDISGQTYNTFHHYNDATYADDVYYDGYVGWNNYAADSYYNGDIYPVINNATVNGVISTYYLDDGISTNTNANSLTIKNSTIHGMITSECMTTDCADDRATGYVYDRLTLSVDNSTIDDNYEHYTYNGTYNNAADTHVVDVYDMGTAITLDQEVDLSITNNSHVAGITLTQGYEWEDIDDNTVSTGVNSSEVFNNTITVKDSTVTSGSWTDEGTTGWFGHTGNASNYSNTLTADDVAIAAIANPYADNAMQTTVTLDNSTLMGDVVFSSNFDENFFPQGANSYRDADGDVDTNGWDGTDRMDVTLNNGSKWVGAAMSVHMVDEDGDGSYDGYAVGTEATATLLDIAANSLWPSSTVGVDNINTQYDENGHIVGNEVYQSGLFNVTLNGGSEWDTTKSSLIDTLSINSGSQVNVADSRLISDTVSLTGGSNLNIGEDGHVATNTLTIDNSTVKMSDDVSAGWGLEDAALYANTITVTNDGLLDINVDQFDANPFQADTLNLTSTTDTNGNIHAGVFDIHSSDYVMDTDLVNDRTNDTTKSNYGYGLIAMNSDGHLTINGNGDNDNTASIEAGQNEVDNNGDHVAAATGNYKVRIDNATGAGSIADYNGNELIYVNDKNSNATFSAANKADLGAYTYQAEQRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGAWVSYFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSGQVDQDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLKAGYDFKLGDAGYVTPYXSISGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYTFTYSEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSAYTDANYLGGGDVDQDWSANVGVKYTW
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Z0469 mutant is attenuated in calves (Dziva et al., 2004).
COG COG3468MU, under M: Cell wall/membrane/envelope biogenesis; U: Intracellular trafficking, secretion, and vesicular transport
References
Dziva et al., 2004: Dziva F, van Diemen PM, Stevens MP, Smith AJ, Wallis TS. Identification of Escherichia coli O157 : H7 genes influencing colonization of the bovine gastrointestinal tract using signature-tagged mutagenesis. Microbiology (Reading, England). 2004; 150(Pt 11); 3631-3645. [PubMed: 15528651].