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mglA

Victor ID 2130
Gene Name mglA
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EDL933
NCBI Gene ID 957113
NCBI Protein GI 15802705
Locus Tag Z3404
Genbank Accession AE005174
Protein Accession NP_288732
Other Database IDs UniProtKB-ID: MGLA_ECO57
UniRef100: UniRef100_Q8X5D9
UniRef90: UniRef90_Q0TFU2
UniRef50: UniRef50_Q0T2X5
UniParc: UPI00000D0CCD
EMBL: AE005174
EMBL: BA000007
EMBL-CDS: AAG57287.1
EMBL-CDS: BAB36464.1
RefSeq_NT: NC_002655.2
RefSeq_NT: NC_002695.1
EnsemblGenome: EBESCG00000028053
EnsemblGenome_TRS: EBESCT00000029002
EnsemblGenome_PRO: EBESCP00000027895
EnsemblGenome: EBESCG00000054682
EnsemblGenome_TRS: EBESCT00000055634
EnsemblGenome_PRO: EBESCP00000053462
GenomeReviews: AE005174_GR
GenomeReviews
Taxonomy ID 155864
Gene Starting Position 3044029
Gene Ending Position 3045549
Gene Strand (Orientation) -
Protein Name galactose/methyl galaxtoside transporter ATP-binding protein
Protein pI 8.43
Protein Weight 53439.492
Protein Length 506
Protein Note with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains
DNA Sequence 
>gi|16445223:3044029-3045549 Escherichia coli O157:H7 str. EDL933 chromosome, complete genome
CTTAAAGGTGCAAAGACGCAAGACGTAGAATTTCGTTTTGCGTTGTTGTTTTTGTATCGACAATTCCGGA
AACGAGGCCATTGCTCATAACCAGAATACGGTCTGTTATCCCTAACAACTCTGGCATTTCAGAGGAGATA
ATAATAATCCCCTTGCCTTTCTTCGCCAGTTCGGCAATTAACTGATAAATCTCAAACTTCGCCCCAACAT
CAATACCGCGCGTCGGTTCATCGARCATTAATATTTCTGGTTGCGTTAACAGCCAGCGCCCAATAATCAC
CTTTTGCTGATTACCACCTGAGAGCGAACCAATTTGCGTCCGATGCCCCGGTGTTTTTACCCGCATCGAA
TCAATCACCCACTGGGTATCGCTTTTCATCCGCGAGTTATCCAGTAAACCAACTTTATTTTTGTAGTTGC
GAATATTGGAAATTAACGAGTTAAAACCAATATCCAGATAGGCATAAATTCCCGTTGAGCGGCGCTCCTC
AGTTACCAGTGCAAATCCGTGGTTTATGGCTTCGTTGGCATTATGGTTATTGATCTTTTTGCCGTGCAAC
GTAATGGTGCCAGCCGATTTCTCGCGAATACCAAATAACGTCTCAACAATATCGGTACGTTTCGCCCCCA
CCAGACCGGCAATACCGAGGATCTCCCCTTTATGCAGATCAAACGAGACATCGCGAATCGACGGCTGGCG
CAGTGACGTCAGGTTACGTACCTCGAGGATGACTTCGCCCGGCTTGTTTTCTTTGTCAGGAAAACGCTGG
TTAAGAGAACGCCCAACCATCATGGCGATAATCTTGTCCATCGTCAGCCCTGCCAGCGGTTCGGTGGCGA
TCCACTGACCGTCGCGCAATACGGTAACTTCATCACATAACTGGAAGATTTCCTCCATTTTATGCGAGAT
ATAAACAATACCGCAGCCGCGCTCTTTTAATTTACGAATAATAGTGAACAGATGATTGACCTCTTTTTCG
GTTAACGAAGAAGTCGGTTCATCCATAATCACAATTTTCGCGTTATAGGAAAACGCTTTGGCGATTTCGA
TCATCTGCATTTGCGAAACAGATAATGTGCCGACGCGCGCACGCGGATCGATATCAATATCCAGTTCATC
AAAAATCGCTTTGGTTTCGCGGTACATTTTGTCCTGATCGACAAACATGCCTTTGGTGGGGTATCGCCCA
AGCCACATGTTGTCCATCACCGAACGTTGTAATACCAGGTTTAACTCCTGGTGTACCATCGAAATACCAT
TTTCCAGTGCTTCTTTGGCCGAATGGAAATCGATCTCTTTACCCTGGAATAAAATGGTGCCGGAGTCTTT
TTTATAAATACCAAACAGGCATTTTAATAATGTTGATTTTCCTGCGCCGTTTTCCCCCATTAATGCATGG
ATAGAATGTGGCCGGACTTTTAAATTAACGTTATCAAGTGCCTTAACACCAGGAAAAGACTTGTTGATAC
CGCTCATTTCCAACAAGTATTCCCCGGAAGACGGAGTCGTTGAGCTGACCA
Protein Sequence 
>gi|15802705|ref|NP_288732.1| galactose/methyl galaxtoside transporter ATP-binding protein [Escherichia coli O157:H7 str. EDL933]
MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYKKDSGTI
LFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDID
IDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKME
EIFQLCDEVTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQPSIR
DVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAINHGFALVTEERRST
GIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDSMRVKTPGHRTQIGSLSGGNQQKVIIGRW
LLTQPEILMXDEPTRGIDVGAKFEIYQLIAELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDT
KTTTQNEILRLASLHL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mglA mutant is attenuated in calves (van et al., 2005).
COG COG1129G, under G: Carbohydrate transport and metabolism
References
van et al., 2005: van Diemen PM, Dziva F, Stevens MP, Wallis TS. Identification of enterohemorrhagic Escherichia coli O26:H- genes required for intestinal colonization in calves. Infection and immunity. 2005; 73(3); 1735-1743. [PubMed: 15731074].