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fadD33 from Mycobacterium tuberculosis H37Rv

Victor ID 213
Gene Name fadD33 from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886855
NCBI Protein GI 15608485
Locus Tag Rv1345
Protein Accession NP_215861.1
Other Database IDs UniProtKB-ID: MBTM_MYCTU
UniRef100: UniRef100_P0A4X9
UniRef90: UniRef90_P0A4X9
UniRef50: UniRef50_Q1BBA2
UniParc: UPI000012A5C7
EMBL: BX842576
EMBL: AE000516
EMBL-CDS: CAA99978.1
EMBL-CDS: AAK45651.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000000834
EnsemblGenome_TRS: EBMYCT00000000834
EnsemblGenome_PRO: EBMYCP00000000834
EnsemblGenome: EBMYCG00000070314
EnsemblGenome_TRS: EBMYCT00000070319
EnsemblGenome_PRO: EBMYCP00000068378
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83332
Gene Starting Position 1509280
Gene Ending Position 1510845
Gene Strand (Orientation) +
Protein Name acyl-CoA synthetase
DNA Sequence 
>gi|57116681:1509280-1510845 Mycobacterium tuberculosis H37Rv, complete genome
GATGAGTGAGCTCGCGGCCGTGCTCACGCGGTCCATGCAGGCCTCTGCCGGCGACTTGATGGTCCTCGAC
CGCGAGACCTCGCTGTGGTGTCGGCACCCGTGGCCCGAGGTACACGGGCTGGCCGAGAGCGTAGCGGCCT
GGCTGCTAGACCATGACCGACCCGCCGCGGTGGGTCTGGTCGGCGAACCGACGGTCGAGTTGGTCGCCGC
GATCCAGGGTGCCTGGCTTGCCGGCGCTGCCGTGTCGATCCTGCCCGGGCCGGTACGTGGCGCCAATGAC
CAGCGATGGGCGGACGCGACGTTGACCCGTTTCCTCGGGATTGGGGTGCGCACCGTATTGAGCCAGGGTT
CCTACCTTGCCCGCCTGCGATCGGTCGATACGGCCGGCGTAACGATCGGAGATCTCAGCACGGCGGCGCA
CACCAATCGTTCGGCCACACCGGTGGCGAGTGAAGGGCCCGCGGTCCTTCAAGGTACCGCGGGATCGACG
GGCGCGCCCCGTACCGCCATCCTTTCGCCGGGCGCGGTGCTCAGCAACTTGCGTGGGCTCAATCAGCGCG
TGGGCACCGATGCTGCGACCGACGTCGGTTGCTCATGGTTACCGCTGTACCACGACATGGGGCTCGCTTT
CGTGCTCTCTGCTGCGCTGGCCGGTGCGCCGCTCTGGTTGGCCCCGACGACGGCGTTCACGGCGTCGCCG
TTCCGTTGGTTGAGTTGGCTCTCGGACAGTGGTGCCACCATGACCGCGGCACCGAACTTCGCCTACAACC
TCATCGGCAAATACGCCAGGCGGGTATCCGAGGTCGACCTGGGTGCCCTGCGAGTGACGCTCAACGGTGG
AGAGCCGGTTGACTGCGATGGGCTGACGCGGTTCGCGGAGGCGATGGCACCGTTCGGATTCGATGCCGGC
GCCGTGTTGCCCTCCTACGGGCTCGCCGAGTCGACGTGCGCGGTGACCGTGCCGGTCCCCGGAATTGGGT
TGCTTGCCGACCGTGTCATCGACGGCAGCGGTGCGCATAAGCACGCGGTCCTGGGTAACCCCATCCCCGG
TATGGAGGTACGGATCTCGTGCGGTGATCAGGCGGCAGGCAATGCGAGCCGTGAAATTGGCGAAATCGAG
ATTCGCGGTGCGTCGATGATGGCGGGTTACCTGGGTCAGCAGCCGATCGACCCTGACGATTGGTTTGCCA
CCGGCGACCTCGGCTATCTTGGCGCTGGCGGCCTGGTGGTGTGTGGTCGCGCGAAGGAAGTCATCTCCAT
CGCGGGACGCAACATCTTTCCGACGGAGGTCGAGCTGGTGGCAGCGCAAGTTCGCGGAGTGCGCGAAGGC
GCCGTGGTCGCCTTGGGCACCGGTGATCGCTCGACCCGCCCCGGTCTGGTGGTCGCGGCCGAGTTCCGCG
GCCCAGACGAGGCGAACGCCCGCGCCGAACTGATCCAACGCGTTGCGTCCGAGTGCGGTATCGTCCCGTC
CGACGTCGTCTTCGTGTCGCCTGGATCACTGCCCCGGACGTCGTCTGGAAAACTGCGCCGCTTGGCAGTC
CGGCGCTCCCTGGAGATGGCGGACTG
Protein Sequence 
>gi|15608485|ref|NP_215861.1| long-chain-fatty-acid--ACP ligase MbtM [Mycobacterium tuberculosis H37Rv] MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fadD33 mutant is attenuated in mice (Rindi et al., 2002).
COG COG0318IQ, under I: Lipid transport and metabolism; Q: Secondary metabolites biosynthesis, transport and catabolism
References
Rindi et al., 2002: Rindi L, Fattorini L, Bonanni D, Iona E, Freer G, Tan D, Dehò G, Orefici G, Garzelli C. Involvement of the fadD33 gene in the growth of Mycobacterium tuberculosis in the liver of BALB/c mice. Microbiology (Reading, England). 2002; 148(Pt 12); 3873-3880. [PubMed: 12480891].