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phoU

Victor ID 2122
Gene Name phoU
Sequence Strain (Species/Organism) Escherichia coli CFT073
NCBI Gene ID 1040241
NCBI Protein GI 161486057
Locus Tag c4648
Genbank Accession AE014075
Protein Accession NP_756506
Other Database IDs UniProtKB-ID: Q8FBT8_ECOL6
UniRef100: UniRef100_E2QHR2
UniRef90: UniRef90_P0A9K7
UniRef50: UniRef50_P0A9K7
UniParc: UPI00000DF2A4
EMBL: AE014075
EMBL-CDS: AAN83080.1
RefSeq_NT: NC_004431.1
EnsemblGenome: EBESCG00000041339.
EnsemblGenome_TRS: EBESCT00000042289
EnsemblGenome_PRO: EBESCP00000040638
GenomeReviews: AE014075_GR
KEGG: ecc:c4648
HOGENOM: HBG725662
OMA: VAIDEEC
ProtClustDB: PRK11115
Taxonomy ID 199310
Gene Starting Position 4407977
Gene Ending Position 4408702
Gene Strand (Orientation) -
Protein Name transcriptional regulator PhoU
Protein pI 4.85
Protein Weight 25802.57
Protein Length 241
Protein Note regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon
DNA Sequence 
>gi|26245917:4407977-4408702 Escherichia coli CFT073, complete genome
ATTATTTATCGCTATCTTTTTCTGCCAGCAGTTTATCGAGCTCGTCACCACCGACGTGACGGAAATCCTG
CCCCTTCACGTAGTAGAAGATAAACTCACAAATATTCTGGCAGCGGTCGCCAATACGTTCGATAGAACGC
GCACAGAATAACGCGGTAAGTACGCTCGGAATGGTACGCGAATCTTCCATCATGTAGGTCATCAGTTGAC
GAACAATACCTTCGTACTCCTGATCGACTTTTTTATCTTCACGATAAATACGTACCGCTTCGTCAATGTC
CATCCGCGCGAACGCGTCCAGCACGTCGTGCAGCATTTGGATGGTATGACGGCCCAGCGACTCCAGACTT
ACCAGCAATGGCTGATGCTGCTGGGAGAATTTCTCCAGTGCAGTACGGCAGATTTTGTCCGCCACGTCGC
CAATACGCTCCAGCTCGGCAATGGTTTTACTGATCACCATAACCAGACGCAGGTCGCTCGCCGTCGGCTG
ACGTTTGGCGATAATGCGCACGCAGGCTTCATCGATCGCCACTTCCATCATGTTGACGTTCTTGTCGCCT
TCGATGACGCGCTTCGCCAGATCGCTGTCCTGGTTATGCATCGCGGTGATTGCATCAGAAAGCTGCTGCT
CCACCATGCCGCCCATGGTCATCACCTGCGTGCGGATGCTTTCCAGTTCGGCGTTGAACTGGCCGGAAAT
ATGTTTATTAAGATTGAGACTGTCCA
Protein Sequence 
>gi|161486057|ref|NP_756506.2| transcriptional regulator PhoU [Escherichia coli CFT073]
MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSDLAKRVIEGDKNVNMMEVAIDE
ACVRIIAKRQPTASDLRLVMVISKTIAELERIGDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLH
DVLDAFARMDIDEAVRIYREDKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNIC
EFIFYYVKGQDFRHVGGDELDKLLAEKDSDK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: phoU mutant is attenuated in mice (Bahrani-Mougeot et al., 2002).
COG COG0704P, under P: Inorganic ion transport and metabolism
References
Bahrani-Mougeot et al., 2002: Bahrani-Mougeot FK, Buckles EL, Lockatell CV, Hebel JR, Johnson DE, Tang CM, Donnenberg MS. Type 1 fimbriae and extracellular polysaccharides are preeminent uropathogenic Escherichia coli virulence determinants in the murine urinary tract. Molecular microbiology. 2002; 45(4); 1079-1093. [PubMed: 12180926].