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hlyA from Escherichia coli CFT073

Victor ID 2110
Gene Name hlyA from Escherichia coli CFT073
Sequence Strain (Species/Organism) Escherichia coli CFT073
NCBI Gene ID 1039496
NCBI Protein GI 26249405
Locus Tag c3570
Protein Accession NP_755445.1
Other Database IDs UniProtKB-ID: Q8FE01_ECOL6
UniRef100: UniRef100_Q8FE01
UniRef90: UniRef90_P08715
UniRef50: UniRef50_P08715
UniParc: UPI00000DEFF6
EMBL: AE014075
EMBL-CDS: AAN82018.1
RefSeq_NT: NC_004431.1
EnsemblGenome: EBESCG00000042561.
EnsemblGenome_TRS: EBESCT00000043511
EnsemblGenome_PRO: EBESCP00000041860
GenomeReviews: AE014075_GR
KEGG: ecc:c3570
NMPDR: fig|199310.1.peg.3488
HOGENOM: HBG296556
OMA: DTAASIN
ProtClustDB: CLSK862058
Taxonomy ID 199310
Gene Starting Position 3418895
Gene Ending Position 3421969
Gene Strand (Orientation) +
Protein Name Hemolysin A
DNA Sequence 
>gi|26245917:3418895-3421969 Escherichia coli CFT073, complete genome
AATGCCAACAATAACCACTGCACAAATTAAAAGCACACTACAGTCTGCAAAGCAATCCTCTGCAAATAAA
TTGCACTCAGCAGGACAAAGCACGAAAGATGCATTAAAAAAAGCAGCAGAGCAAACCCGCAATGCGGGAA
ACAGACTCATTTTACTTATCCCTAAAGATTATAAAGGACAGGGTTCAAGCCTTAATGACCTTGTCAGGAC
GGCAGATGAACTGGGAATTGAAGTCCAGTATGATGAAAAGAATGGCACGGCGATTACTAAACAGGTATTC
GGCACAGCAGAGAAACTCATTGGCCTCACCGAACGGGGAGTGACTATCTTTGCACCACAATTAGACAAAT
TACTGCAAAAGTATCAAAAAGCGGGTAATAAATTAGGCGGCAGTGCTGAAAATATAGGTGATAACTTAGG
AAAGGCAGGCAGTGTACTGTCAACGTTTCAAAATTTTCTGGGTACTGCACTTTCCTCAATGAAAATAGAC
GAACTGATAAAGAGACAAAAATCTGGTAGCAATGTCAGTTCTTCTGAACTGGCAAAAGCGAGTATTGAGC
TAATCAACCAACTCGTGGACACAGCTGCCAGCATTAATAATAATGTTAACTCATTTTCTCAACAACTCAA
TAAGCTGGGAAGTGTATTATCCAATACAAAGCACCTGACCGGTGTTGGTAATAAGTTACAGAATTTACCT
AACCTTGATAATATCGGTGCAGGGTTAGATACTGTATCGGGTATTTTATCTGCGATTTCAGCAAGCTTCA
TTCTGAGCAATGCAGATGCAGATACCGGAACTAAAGCTGCAGCAGGTGTTGAATTAACAACGAAAGTACT
GGGTAATGTTGGAAAAGGTATTTCTCAATATATTATCGCACAGCGCGCTGCACAGGGATTATCTACATCT
GCTGCTGCTGCCGGTTTAATTGCTTCTGTAGTGACATTAGCAATTAGTCCCCTCTCATTCCTGTCCATTG
CCGATAAGTTTAAACGTGCCAATAAAATAGAGGAGTATTCACAACGATTCAAAAAACTTGGATACGATGG
TGACAGTTTACTTGCTGCTTTTCACAAAGAAACAGGAGCTATTGATGCATCGTTAACAACGATAAGCACT
GTTCTGGCTTCAGTATCTTCAGGTATTAGTGCTGCTGCAACGACATCTCTGGTTGGTGCACCGGTAAGCG
CGCTGGTAGGGGCTGTTACGGGGATAATTTCAGGCATCCTTGAGGCTTCAAAACAGGCAATGTTTGAACA
TGTCGCCAGTAAAATGGCCGATGTTATTGCTGAATGGGAGAAAAAACACGGCAAAAATTACTTTGAAAAT
GGATATGATGCCCGCCATGCTGCATTTTTAGAAGATAACTTTAAAATATTATCTCAGTATAATAAAGAGT
ATTCTGTTGAAAGATCAGTCCTCATTACCCAGCAACATTGGGATACGCTGATAGGTGAGTTAGCGGGTGT
CACCAGAAATGGAGACAAAACACTCAGTGGTAAAAGTTATATTGACTATTATGAAGAAGGAAAACGTCTG
GAGAAAAAACCGGATGAATTCCAGAAGCAAGTCTTTGACCCATTGAAAGGAAATATTGACCTTTCTGACA
GCAAATCTTCTACGTTATTGAAATTTGTTACGCCATTGTTAACTCCCGGTGAGGAAATTCGTGAAAGGAG
GCAGTCCGGAAAATATGAATATATTACCGAGTTATTAGTCAAGGGTGTTGATAAATGGACGGTGAAGGGG
GTTCAGGACAAGGGGTCTGTATATGATTACTCTAACCTGATTCAGCATGCATCAGTCGGTAATAACCAGT
ATCGGGAAATTCGTATTGAGTCACACCTGGGAGACGGGGATGATAAGGTCTTTTTATCTGCCGGCTCAGC
CAATATCTACGCAGGTAAAGGACATGATGTTGTTTATTATGATAAAACAGACACCGGTTATCTGACCATT
GATGGCACAAAAGCAACCGAAGCGGGTAATTACACGGTAACACGTGTACTTGGTGGTGATGTTAAGATTT
TACAGGAAGTTGTGAAGGAGCAGGAGGTTTCAGTTGGAAAAAGAACTGAAAAAACGCAATATCGGAGTTA
TGAATTCACTCATATCAATGGTAAAAATTTAACAGAGACTGATAACTTATATTCCGTGGAAGAACTTATT
GGGACCACGCGTGCCGACAAGTTTTTTGGCAGTAAATTTACTGATATCTTCCATGGCGCGGATGGTGATG
ACCATATAGAAGGAAATGATGGGAATGACCGCTTATATGGTGATAAAGGTAATGATACGCTGAGGGGCGG
AAACGGGGATGACCAGCTCTATGGCGGTGATGGCAATGATAAGTTAATTGGGGGGACAGGTAATAATTAC
CTTAACGGCGGTGACGGAGATGATGAGCTTCAGGTTCAGGGGAATTCTCTTGCTAAAAATGTATTATCCG
GTGGAAAAGGTAATGACAAGTTGTACGGCAGTGAGGGAGCAGATCTGCTTGATGGCGGAGAAGGGAATGA
TCTTCTGAAAGGTGGATATGGTAATGATATTTATCGTTATCTTTCAGGATATGGCCATCATATTATTGAC
GATGATGGGGGGAAAGACGATAAACTCAGTTTGGCTGATATTGATTTCCGGGATGTGGCCTTCAGGCGAG
AAGGTAATGACCTCATCATGTATAAAGCTGAAGGTAATGTTCTTTCCATTGGTCATAAAAATGGTATTAC
ATTCAGGAACTGGTTTGAAAAAGAGTCAGGTGATATCTCTAATCACCAGATAGAGCAGATTTTTGATAAA
GACGGCAGGGTAATCACACCAGATTCCCTTAAAAAGGCACTTGAGTATCAACAGAGTAATAATAAGGCAA
GTTATGTGTATGGGAATGATGCATTAGCCTATGGAAGTCAGGATAATCTTAATCCATTAATTAATGAAAT
CAGCAAAATCATTTCAGCTGCAGGTAATTTTGATGTTAAAGAGGAAAGAGCTGCAGCTTCTTTATTGCAG
TTGTCCGGTAATGCCAGTGATTTTTCATATGGACGGAACTCAATAACTTTGACAGCATCAGCATA
Protein Sequence 
>gi|26249405|ref|NP_755445.1| hemolysin A [Escherichia coli CFT073] MPTITTAQIKSTLQSAKQSSANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQGSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGNKLGGSAENIGDNLGKAGSVLSTFQNFLGTALSSMKIDELIKRQKSGSNVSSSELAKASIELINQLVDTAASINNNVNSFSQQLNKLGSVLSNTKHLTGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADTGTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKPDEFQKQVFDPLKGNIDLSDSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGSVYDYSNLIQHASVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKILQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIFHGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGNNYLNGGDGDDELQVQGNSLAKNVLSGGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDIYRYLSGYGHHIIDDDGGKDDKLSLADIDFRDVAFRREGNDLIMYKAEGNVLSIGHKNGITFRNWFEKESGDISNHQIEQIFDKDGRVITPDSLKKALEYQQSNNKASYVYGNDALAYGSQDNLNPLINEISKIISAAGNFDVKEERAAASLLQLSGNASDFSYGRNSITLTASA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in zebra fish (Wiles et al., 2009).
COG COG2931Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Wiles et al., 2009: Wiles TJ, Bower JM, Redd MJ, Mulvey MA. Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli. PLoS pathogens. 2009; 5(12); e1000697. [PubMed: 20019794].