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manB from Escherichia coli CFT073

Victor ID 2107
Gene Name manB from Escherichia coli CFT073
Sequence Strain (Species/Organism) Escherichia coli CFT073
NCBI Gene ID 1037835
NCBI Protein GI 26248405
Locus Tag c2557
Protein Accession NP_754445.1
Other Database IDs UniProtKB-ID: Q8FG43_ECOL6
UniRef100: UniRef100_Q9EXX8
UniRef90: UniRef90_P37742
UniRef50: UniRef50_P37742
UniParc: UPI00000B1E09
EMBL: AE014075
EMBL-CDS: AAN81012.1
RefSeq_NT: NC_004431.1
HSSP: P26276
EnsemblGenome: EBESCG00000040867.
EnsemblGenome_TRS: EBESCT00000041817
EnsemblGenome_PRO: EBESCP00000040166
GenomeReviews: AE014075_GR
KEGG: ecc:c2557
HOGENOM: HBG644964
OMA: PNPLLVE
ProtClustDB: CLSK880273
Taxonomy ID 199310
Gene Starting Position 2389573
Gene Ending Position 2390943
Gene Strand (Orientation) -
Protein Name Phosphomannomutase
DNA Sequence 
>gi|26245917:2389573-2390943 Escherichia coli CFT073, complete genome
ATTACTTGTTCAGTAACTCAAGGATAAGTTTTGTCTTTTCTTCCATCAGCGGTACATCGCCGCGCGATTC
CACATTCAACCGCACCACCGGTTCGGTGTTGGAGGAGCGCAGGTTAAAGCGCCAGTCGGCAAAGGTCATG
CTGATGCCATCGGTACGATCCACCGCCAGCGCCTCACGGCTAAAATGCTGTTCCACGCGGTTAATCGCCT
CAACGGGTTGCGCCAGTTTGCTGTTGATCTCACCGCTTGCCGGAAACGCTGCCATCCGGTCGCGCACCAG
TTCGCCCAGCGTTTTTCCTTTCAGGCACACCAGTTCGGCGACCAGCAGCCACGGGATCATGCCGCTGTCG
CAGTAAGCGAAATCACGGAAGTAATGGTGGGCGCTCATTTCGCCACCGTAGATAGCGTCTTCCTTGCGCA
TACGTTCTTTAATAAAGGCGTGTCCGGTTTTCGACATTACCGGGGTGCCGCCTGCGGCAGTCACCACATC
AACGGTGTTCCAGGAGAGACGTGGATCGTGGATGATCTTCGCGCCGGGATTTTTTTCGAGGAACGCTTCT
GCCAGCAGGCCGACAATGTAGTAGCCCTCAATAAACTGCCCTTTTTCGTCAAACAGGAAACAGCGGTCAA
AATCGCCATCAAAGGCAATGCCCATATCCGCGCCGTGTTTGATGACCGCATTGCGGGTGTCGTCGCGACA
TTCCGGCAGTAGCGGGTTAGGAATACCGTTGGGGAAATTGCCGTCCGGCGTGTTGTGCACTTTGATTAAT
TCCACGGGTGCGCCGAGGGCTTTAAAGCGGGCTTCAATGGCGTCCACCACCGGACCCGCCGCGCCGTTCC
CGGAGTTAATCACCAGCTTGAGCGGCGTGAGGTTTTTGACGTTGATATAACCGAACAGGTGATCAACGTA
AGCGTCACGCAGATTGATTTGCTGATAGCGACCGCGTTTGGTTTCATCAACGGGAGGAAAGTCGTTGGCT
TCTGCCAGACGCTGGATGTCGCGCAGTCCGGTATCACCGCTGATCGGGCGAGCCCCTTCGCGCACCAGTT
TCATGCCGTTGTAATCCATCGGGTTATGGCTGGCGGTAACTTCGATGCCGCCATCCACGCCGAGATGGAA
CGTGGCGAAATAGATTTCTTCGGTGCCGGACATGCCAATATCCAGCACATCGACGCCCGCATCCTGTAAC
CCCTTCGCCAGCGCCAGTTTTAAGGTTTCGCTGGTGAGTCGGACGTCACCGCCTAACACAATGGTTTTCG
GTTTGAGAAATTCGCCATAAGCGCGACCAATGCGCCAGGCAATATCTTCATTCAGTTCTTCGCCTAATTT
CCCGCGAATATCATAGGCTTTAAAGCAGGGTAAACTCGACA
Protein Sequence 
>gi|26248405|ref|NP_754445.1| phosphomannomutase [Escherichia coli CFT073] MSSLPCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLGGDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDIQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLFGYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIPNPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAQPVEAINRVEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEEKTKLILELLNK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: manB mutant is attenuated in mice (Bahrani-Mougeot et al., 2002).
COG COG1109G, under G: Carbohydrate transport and metabolism
References
Bahrani-Mougeot et al., 2002: Bahrani-Mougeot FK, Buckles EL, Lockatell CV, Hebel JR, Johnson DE, Tang CM, Donnenberg MS. Type 1 fimbriae and extracellular polysaccharides are preeminent uropathogenic Escherichia coli virulence determinants in the murine urinary tract. Molecular microbiology. 2002; 45(4); 1079-1093. [PubMed: 12180926].