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wecE

Victor ID 2095
Gene Name wecE
Sequence Strain (Species/Organism) Escherichia coli CFT073
NCBI Gene ID 1036493
NCBI Protein GI 26250530
Locus Tag c4711
Genbank Accession AE014075
Protein Accession NP_756570
Other Database IDs UniProtKB-ID: Q8FBQ2_ECOL6
UniRef100: UniRef100_E2QHW7
UniRef90: UniRef90_E2QHW7
UniRef50: UniRef50_P27833
UniParc: UPI00000DF2C7
EMBL: AE014075
EMBL-CDS: AAN83144.1
RefSeq_NT: NC_004431.1
HSSP: Q8ZNF3
EnsemblGenome: EBESCG00000043929.
EnsemblGenome_TRS: EBESCT00000044879
EnsemblGenome_PRO: EBESCP00000043228
GenomeReviews: AE014075_GR
KEGG: ecc:c4711
NMPDR: fig|199310.1.peg.4613
HOGENOM: HBG660897
OMA: VHYAGVS
ProtClustDB: PRK11706
Taxonomy ID 199310
Gene Starting Position 4475309
Gene Ending Position 4476439
Gene Strand (Orientation) +
Protein Name TDP-4-oxo-6-deoxy-D-glucose transaminase
Protein pI 6.31
Protein Weight 39834.53
Protein Length 376
Protein Note catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis
DNA Sequence 
>gi|26245917:4475309-4476439 Escherichia coli CFT073, complete genome
CATGATTCCATTTAACGCACCGCCGGTGGTGGGAACCGAACTCGACTATATGCAGTCGGCAATGGGTAGC
GGCAAACTGTGCGGCGATGGTGGTTTTACCCGTCGCTGCCAGCAGTGGCTGGAGCAACGTTTTGGCAGCG
CCAAAGTGTTACTGACGCCATCCTGTACCGCTTCGCTGGAGATGGCGGCGCTGCTGCTCGATATCCAGCC
TGGCGATGAAGTGATCATGCCGAGCTACACCTTTGTCTCCACCGCCAATGCCTTTGTGCTGCGTGGCGCG
AAAATCGTCTTTGTGGATGTTCGCCCGGACACCATGAACATCGACGAAACGCTGATTGAAGCGGCGATCA
CCGACAAAACGCGCGTTATCGTGCCGGTCCATTACGCGGGTGTGGCCTGCGAAATGGACACCATTATGGC
GTTGGCGAAGAAGCATAATCTGTTTGTGGTGGAAGATGCCGCTCAGGGCGTGATGTCCACTTACAAAGGG
CGTGCGCTGGGAACCATTGGTCATATTGGCTGCTTTAGCTTCCATGAAACCAAAAACTACACGGCGGGTG
GTGAAGGCGGCGCGACGCTGATTAACGATAAAGCGTTGATCGAACGAGCCGAGATCATCCGTGAAAAAGG
CACAAACCGCAGCCAGTTCTTCCGTGGTCAGGTCGATAAATATACCTGGCGCGATATTGGCTCCAGCTAT
TTGATGTCCGATCTGCAAGCTGCGTACCTGTGGGCGCAACTGGAAGCTGCGGATCGTATCAACCAGCAAC
GTCTGGCGCTGTGGCAAAACTACTACGATGCGCTGGCGCCTCTGGCAAAAAATGGGCGTATCGAGCTGCC
GTCGATTCCCGATGGCTGCGTGCAGAACGCGCATATGTTCTACATTAAACTGCGGGATATTGCTGACCGG
AGCGCATTGATTAACTTTCTGAAAGAAGCGGAAATCATGGCGGTGTTCCATTACATTCCGCTGCACGGTT
GCCCTGCGGGGGAACGCTTTGGTGAGTTCCACGGCGAAGATCGCTACACCACCAAAGAGAGCGAGCGCCT
GCTGCGCCTGCCGTTGTTCTACAACCTGTCGCCCGTCAATCAGCGTACGGTAATTGCGACCTTGTTGAAC
TACTTCTCCTG
Protein Sequence 
>gi|26250530|ref|NP_756570.1| TDP-4-oxo-6-deoxy-D-glucose transaminase [Escherichia coli CFT073]
MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRFGSAKVLLTPSCTASLEMAALLLDIQP
GDEVIMPSYTFVSTANAFVLRGAKIVFVDVRPDTMNIDETLIEAAITDKTRVIVPVHYAGVACEMDTIMA
LAKKHNLFVVEDAAQGVMSTYKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKG
TNRSQFFRGQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKNGRIELP
SIPDGCVQNAHMFYIKLRDIADRSALINFLKEAEIMAVFHYIPLHGCPAGERFGEFHGEDRYTTKESERL
LRLPLFYNLSPVNQRTVIATLLNYFS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: wecE mutant is attenuated in mice (Bahrani-Mougeot et al., 2002).
COG COG0399M, under M: Cell wall/membrane/envelope biogenesis
References
Bahrani-Mougeot et al., 2002: Bahrani-Mougeot FK, Buckles EL, Lockatell CV, Hebel JR, Johnson DE, Tang CM, Donnenberg MS. Type 1 fimbriae and extracellular polysaccharides are preeminent uropathogenic Escherichia coli virulence determinants in the murine urinary tract. Molecular microbiology. 2002; 45(4); 1079-1093. [PubMed: 12180926].