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tonB from Escherichia coli CFT073

Victor ID 2092
Gene Name tonB from Escherichia coli CFT073
Sequence Strain (Species/Organism) Escherichia coli CFT073
NCBI Gene ID 1035499
NCBI Protein GI 26247582
Locus Tag c1717
Protein Accession NP_753622.1
Other Database IDs UniProtKB-ID: Q8FHW5_ECOL6
UniRef100: UniRef100_B7MU40
UniRef90: UniRef90_P02929
UniRef50: UniRef50_P25945
UniParc: UPI00000DEB11
EMBL: AE014075
EMBL-CDS: AAN80184.1
RefSeq_NT: NC_004431.1
HSSP: P94739
EnsemblGenome: EBESCG00000042454.
EnsemblGenome_TRS: EBESCT00000043404
EnsemblGenome_PRO: EBESCP00000041753
GenomeReviews: AE014075_GR
KEGG: ecc:c1717
HOGENOM: HBG473783
OMA: MIMTSIT
ProtClustDB: PRK10819
Taxonomy ID 199310
Gene Starting Position 1554964
Gene Ending Position 1555731
Gene Strand (Orientation) +
Protein Name membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins
DNA Sequence 
>gi|26245917:1554964-1555731 Escherichia coli CFT073, complete genome
TTTGCATTTAAAATCGGGGCCTGGTTTTTCTACTGAAATGATTATGACTTCAATGACCCTTGATTTACCT
CGCCGCTTCCCCTGGCCGACGTTACTTTCGGTCTGCATTCATGGTGCTGTTGTGGCGGGTTTGCTCTATA
CCTCGGTACATCAGGTTATTGAACTACCTGCGCCTGCGCAGCCGATTTCTGTCACGATGGTTGCGCCTGC
TGATCTTGAACCGCCACAAGCCGTTCAGCCACCACCGGAGCCGGTGGTAGAGCCAGAACCGGAACCTGAG
CCGATCCCTGAACCGCCAAAAGAAGCTCCGGTGGTCATTGAAAAGCCGAAGCCGAAACCTAAGCCAAAAC
CGAAGCCGGTGAAAAAGGTGGAGCAGCCAAAACGCGATGTCAAACCCGTAGAGTCGCGTCCGGCATCACC
GTTTGAAAATACGGCACCCGCGCGCCCGACATCAAGTACGGCAACGGCTGCAACCAGCAAGCCGGTTACC
AGTGTGGCTTCAGGACCACGCGCATTAAGCCGTAATCAGCCGCAGTATCCGGCACGAGCACAGGCATTGC
GCATTGAAGGGCAGGTTAAAGTTAAATTTGATGTCACGCCAGATGGTCGCGTGGATAACGTACAAATCCT
CTCAGCCAAGCCTGCAAACATGTTTGAGCGTGAGGTGAAAAATGCGATGCGCAGATGGCGTTATGAGCCG
GGTAAGCCAGGCAGTGGGATTGTGGTGAATATCCTGTTTAAAATTAACGGCACTACCGAAATTCAGTA
Protein Sequence 
>gi|26247582|ref|NP_753622.1| transport protein TonB [Escherichia coli CFT073] MHLKSGPGFSTEMIMTSMTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Torres et al., 2001).
COG COG0810M, under M: Cell wall/membrane/envelope biogenesis
References
Torres et al., 2001: Torres AG, Redford P, Welch RA, Payne SM. TonB-dependent systems of uropathogenic Escherichia coli: aerobactin and heme transport and TonB are required for virulence in the mouse. Infection and immunity. 2001; 69(10); 6179-6185. [PubMed: 11553558].