Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

iroN from Escherichia coli CFT073

Victor ID 2088
Gene Name iroN from Escherichia coli CFT073
Sequence Strain (Species/Organism) Escherichia coli CFT073
NCBI Gene ID 1034931
NCBI Protein GI 26247124
Locus Tag c1250
Protein Accession NP_753164.1
Other Database IDs UniProtKB-ID: Q8CY02_ECOL6
UniRef100: UniRef100_Q9RQ19
UniRef90: UniRef90_Q93K73
UniRef50: UniRef50_Q05098
UniParc: UPI00000AE976
EMBL: AE014075
EMBL-CDS: AAN79707.1
RefSeq_NT: NC_004431.1
HSSP: P05825
EnsemblGenome: EBESCG00000041362.
EnsemblGenome_TRS: EBESCT00000042312
EnsemblGenome_PRO: EBESCP00000040661
GenomeReviews: AE014075_GR
KEGG: ecc:c1250
NMPDR: fig|199310.1.peg.1207
HOGENOM: HBG464298
OMA: TMVVEST
ProtClustDB: PRK13528
Taxonomy ID 199310
Gene Starting Position 1198161
Gene Ending Position 1200338
Gene Strand (Orientation) +
Protein Name Siderophore receptor IroN
DNA Sequence 
>gi|26245917:1198161-1200338 Escherichia coli CFT073, complete genome
AATGAGAATTAACAAAATCCTCTGGTCGCTAACTGTGCTCCTAGTTGGGTTGAATAGCCAGGTATCAGTA
GCCAAATACTCCGACGATGATAATGACGAGACTCTGGTGGTGGAAGCCACCGCTGAGCAGGTATTAAAAC
AGCAGCCGGGCGTGTCGGTTATTACCAGCGAGGATATTAAAAAGACCCCTCCGGTAAACGACCTTTCAGA
TATTATTCGTAAAATGCCTGGTGTTAATCTTACCGGCAATAGCGCCTCGGGCACACGCGGTAATAACCGC
CAGATCGATATTCGTGGTATGGGGCCGGAAAACACCTTAATTTTAATTGATGGTGTACCGGTGACGTCAC
GTAACTCCGTGCGTTATAGCTGGCGTGGGGAGCGTGATACCCGCGGTGACACCAACTGGGTGCCACCGGA
ACAGGTTGAGCGTATTGAAGTGATCCGCGGCCCTGCGGCGGCGCGCTACGGTTCGGGGGCCGCCGGGGGG
GTGGTGAACATCATTACCAAACGTCCCACCAACGACTGGCACGGTTCGCTGTCGTTATACACCAACCAGC
CGGAAAGTAGCGAAGAGGGCGCTACGCGTCGCGCCAATTTCAGCCTTAGTGGGCCTCTGGCTGGTGATGC
TCTTACCACGCGTTTGTATGGTAACCTGAATAAAACGGATGCTGACAGTTGGGATATTAATTCTCCGGTC
GGTACGAAAAACGCAGCCGGGCATGAAGGGGTACGTAACAAAGATATTAACGGCGTTGTCTCGTGGAAAT
TAAATCCGCAGCAGATTCTCGATTTCGAAGTCGGATATAGCCGCCAGGGGAATATCTATGCGGGCGATAC
GCAGAACAGTTCTTCCAGTGCAGTTACCGAAAGCCTGGCAAAATCCGGCAAAGAGACGAACCGCCTGTAC
CGACAGAATTATGGCATTACGCATAATGGTATCTGGGACTGGGGACAAAGTCGCTTTGGTGTTTATTACG
AGAAAACCAATAATACCCGCATGAATGAAGGATTATCCGGCGGTGGTGAAGGACGTATTTTAGCGGGTGA
AAAGTTTACGACCAATCGCCTGAGTTCCTGGCGAACCAGCGGTGAGCTTAATATTCCTTTGAATGTGATG
GTTGATCAAACGCTGACCGTTGGTGCAGAGTGGAACCGCGATAAGCTCGATGATCCTTCCTCTACCAGCC
TGACGGTGAATGACAGAGATATCAGCGGTATTTCTGGCTCTGCTGCGGATCGCAGCAGTAAAAATCATTC
TCAAATCAGTGCGCTGTATATTGAAGATAACATTGAGCCGGTTCCTGGCACGAATATCATTCCCGGCCTG
CGCTTTGATTATCTCAGCGACTCCGGCGGGAACTTCAGCCCCAGTCTGAATCTTTCGCAGGAATTGGGCG
ATTATTTCAAAGTCAAAGCAGGGGTTGCCCGAACCTTTAAAGCCCCAAACCTGTATCAATCCAGTGAAGG
CTATCTGCTCTACTCGAAAGGCAATGGCTGTCCAAAAGATATTACATCAGGCGGGTGCTACCTGATCGGT
AATAAAGATCTCGATCCGGAAATCAGCGTCAATAAAGAAATTGGACTGGAGTTCACCTGGGAAGATTACC
ACGCAAGTGTGACCTACTTCCGCAATGATTACCAGAATAAGATCGTGGCCGGGGATAACGTTATCGGGCA
AACCGCTTCAGGCGCATATATCCTCAAGTGGCAGAATGGCGGGAAAGCTCTGGTGGACGGTATCGAAGCC
AGTATGTCTTTCCCACTGGTGAAAGAGCGTCTGAACTGGAATACCAATGCCACATGGATGATCACTTCGG
AGCAAAAAGACACCGGTAATCCTCTGTCGGTCATCCCGAAATATACTATCAATAACTCGCTTAACTGGAC
CATCACCCAGGCGTTTTCTGCCAGCTTCAACTGGACGTTATATGGCAGACAAAAACCGCGTACTCATGCG
GAAACCCGCAGTGAAGATACTGGCGGTCTGTCAGGTAAAGAGCTGGGCGCTTATTCACTGGTGGGGACGA
ACTTCAATTACGATATTAATAAAAATCTGCGTCTTAATGTCGGCGTCAGTAATATCCTCAATAAACAGAT
CTTCCGATCTTCTGAAGGGGCGAATACCTATAACGAGCCAGGCCGGGCTTATTATGCCGGAGTTACCGCA
TCATTCTG
Protein Sequence 
>gi|26247124|ref|NP_753164.1| outer membrane receptor FepA [Escherichia coli CFT073] MRINKILWSLTVLLVGLNSQVSVAKYSDDDNDETLVVEATAEQVLKQQPGVSVITSEDIKKTPPVNDLSDIIRKMPGVNLTGNSASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAAGGVVNIITKRPTNDWHGSLSLYTNQPESSEEGATRRANFSLSGPLAGDALTTRLYGNLNKTDADSWDINSPVGTKNAAGHEGVRNKDINGVVSWKLNPQQILDFEVGYSRQGNIYAGDTQNSSSSAVTESLAKSGKETNRLYRQNYGITHNGIWDWGQSRFGVYYEKTNNTRMNEGLSGGGEGRILAGEKFTTNRLSSWRTSGELNIPLNVMVDQTLTVGAEWNRDKLDDPSSTSLTVNDRDISGISGSAADRSSKNHSQISALYIEDNIEPVPGTNIIPGLRFDYLSDSGGNFSPSLNLSQELGDYFKVKAGVARTFKAPNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKDLDPEISVNKEIGLEFTWEDYHASVTYFRNDYQNKIVAGDNVIGQTASGAYILKWQNGGKALVDGIEASMSFPLVKERLNWNTNATWMITSEQKDTGNPLSVIPKYTINNSLNWTITQAFSASFNWTLYGRQKPRTHAETRSEDTGGLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNILNKQIFRSSEGANTYNEPGRAYYAGVTASF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iroA gene cluster mutants were unable to resist Lcn2 in mouse serum (Fischbach et al., 2006).
COG COG4771P, under P: Inorganic ion transport and metabolism
References
Fischbach et al., 2006: Fischbach MA, Lin H, Zhou L, Yu Y, Abergel RJ, Liu DR, Raymond KN, Wanner BL, Strong RK, Walsh CT, Aderem A, Smith KD. The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(44); 16502-16507. [PubMed: 17060628].