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aslA from Escherichia coli UTI89

Victor ID 2083
Gene Name aslA from Escherichia coli UTI89
Sequence Strain (Species/Organism) Escherichia coli UTI89
NCBI Gene ID 3992515
NCBI Protein GI 91213321
Locus Tag UTI89_C4359
Protein Accession YP_543307.1
Other Database IDs UniProtKB-ID: Q1R4D8_ECOUT
UniRef100: UniRef100_E2QHX4
UniRef90: UniRef90_P25549
UniRef50: UniRef50_P25549
UniParc: UPI00000DF2CE
EMBL: CP000243
EMBL-CDS: ABE09776.1
RefSeq_NT: NC_007946.1
EnsemblGenome: EBESCG00000065579.
EnsemblGenome_TRS: EBESCT00000066532
EnsemblGenome_PRO: EBESCP00000064010
GenomeReviews: CP000243_GR
KEGG: eci:UTI89_C4359
eggNOG: COG3119
HOGENOM: HBG374065
OMA: PTRATIM
ProtClustDB: CLSK880785
BioCyc: ECOL364106:UTI89_C4359-MONOMER
Taxonomy ID 364106
Gene Starting Position 4244344
Gene Ending Position 4245999
Gene Strand (Orientation) -
Protein Name arylsulfatase
DNA Sequence 
>gi|91209055:4244344-4245999 Escherichia coli UTI89, complete genome
CTTAGTCAGATTTAATCTGCGCGCGTGGTGGATATTTTTTCAGGATCTCCATATACGCGTGCATTTCGGT
CTGTAGCGGTACACCCATCGGAATATGGCGCACGCCGATAGAGTCGCTTTCCTGCGGATCGGTGTACAGG
TTAAACACCGACGATCCCGCCGTTTGCATTACTGTGCCGGTGAATCCACCCTGATATCCGCTCTGGGTAT
AAGCGTAAGGTTGCTGAATCAGGACGTGATACTTGAACTCATCCATACGCACAGCAGAAAGTTTACCGTT
GAGGAAGTAGTGCTCGGCCTTACGGTTAGACTGACCATTTGTTCCCAGGAAGAAAGATGTCTGGTCCACA
CCATCGATAAAGGTGGTTTTCGGTACTAAATTCGCTACTTTCGCCCCAGGATGCCCCGCCAGATCCAGCG
CCGTAGGGAAGAGATCCGCCAGATCGACAATGCCGTCAGATTTACGCGGTTGGATCATGCCTTTCCAGTA
AACGAAGGTTGGCACACGAACGCCGCCTTCCCATGTAGAACCTTTCGCACCGCGGAACGGCGTGCGACCG
TGCGGCGGAACTTCGGCTTCCGGACCGTTATCAGAGGTGAACACAATCAGCGTGTTATCAAGCTGACCGT
TTTTCTCCAGTGCTTTATACAGATTGGCGAAGATATCGTTCATCTCCACCATGCAGTCGCCGTAAGAGGT
GCGCGCCGGAGAGCTACCCGCATATTTGGCGTTCGGGTAGTTATCGAAGTGACAGCCGCGAGTGCCGTAA
TAGAGGAAGAAAGGCTTATCACTCTTCGCCATCTTGTCGAGGAACTTAACGCCATATTCCATCCAGCGTT
GATCCAGGTCTTCCATATATTTCGGCGTAATGTCGGCAATGGCTTCCTGTTCACCGCCGCGCACGGCATG
AACGTCATCTTTGCTGAACGGCAGTTTTTGGATGTATTCAGAACGAGCCGGGCTCAGGGCGACTTCCGGG
TTGACATGAACATCACGCCATTCGGTATACATATCGGACACCGAGTTAAAGCCGCGGAAATCATCAAAGC
CAACGTTCTGCGGCTGCGACTCTTTGTTTTCCCCCATATGCCATTTCCCGATAGCCTGGGTGACGTAGCC
CTGATCGTGCAGCAACTGCGGCAGCGTGGTTAACCCTTGCAGACCGCCCGGTTGCCCGTACATTGGCGGC
ATCAGAATGCCGTGGTGGATGGAGTATTGTCCGGTGAGAATCGTGGCGCGGGTTGGGGAAGAACTCGGTT
GAGAATACGCCGAAGTTAAAATCAGCCCCTGGCTGGCAACGGCGTCGATATCTGGTGTAGGGTTACCCAC
CGCCACGCCGCCGCCGTTAAAGCCAACGTCCATCCAGCCCACATCATCCAGCAAGAAAACAACCACGTTC
GGTTTCTTACCGGTTTTTTTCTCAAGTTCCGCCAGTTTCTGCTGGGTTTCTTTGTCTTGTGCAGGATGCT
GCATCACCGGCATCATGTTGTCGGCAATAGTGGTCGCCGGTTTAACCAGATACTGGTTTGGGTGATCGTA
TCCGGCAAAGCCTTTGCGTGCGGTGGCGGTTGACGGGGTATCTGCTGCGCTGGCTATGAGAGGAAGAGCT
GCGGCGACAGCAACAACAAGAAGTTTGGGTGAAAACGAAAATTCCA
Protein Sequence 
>gi|91213321|ref|YP_543307.1| arylsulfatase [Escherichia coli UTI89] MEFSFSPKLLVVAVAAALPLIASAADTPSTATARKGFAGYDHPNQYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVGFNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMYGQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYTEWRDVHVNPEVALSPARSEYIQKLPFSKDDVHAVRGGEQEAIADITPKYMEDLDQRWMEYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDIFANLYKALEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWKGMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQSNRKAEHYFLNGKLSAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLYTDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: disruption mutant was less invasive in an in vitro HBMEC invasion assay than the wild-type E. coli K1 (Hoffman et al., 2000).
COG COG3119P, under P: Inorganic ion transport and metabolism
References
Hoffman et al., 2000: Hoffman JA, Badger JL, Zhang Y, Huang SH, Kim KS. Escherichia coli K1 aslA contributes to invasion of brain microvascular endothelial cells in vitro and in vivo. Infection and immunity. 2000; 68(9); 5062-5067. [PubMed: 10948126].