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ibeA from Escherichia coli UTI89

Victor ID 2082
Gene Name ibeA from Escherichia coli UTI89
Sequence Strain (Species/Organism) Escherichia coli UTI89
NCBI Gene ID 3992253
NCBI Protein GI 91213983
Locus Tag UTI89_C5035
Protein Accession YP_543969.1
Other Database IDs UniProtKB-ID: Q1R2H6_ECOUT
UniRef100: UniRef100_Q6X972
UniRef90: UniRef90_Q659Z2
UniRef50: UniRef50_Q9FCY5
UniParc: UPI000035D6B7
EMBL: CP000243
EMBL-CDS: ABE10438.1
RefSeq_NT: NC_007946.1
EnsemblGenome: EBESCG00000067815.
EnsemblGenome_TRS: EBESCT00000068768
EnsemblGenome_PRO: EBESCP00000066246
GenomeReviews: CP000243_GR
KEGG: eci:UTI89_C5035
eggNOG: NOG27896
HOGENOM: HBG583717
OMA: IPPCMAM
ProtClustDB: CLSK767238
BioCyc: ECOL364106:UTI89_C5035-MONOMER
Taxonomy ID 364106
Gene Starting Position 4937130
Gene Ending Position 4938500
Gene Strand (Orientation) +
Protein Name invasion protein IbeA
DNA Sequence 
>gi|91209055:4937130-4938500 Escherichia coli UTI89, complete genome
TATGGAATTTTATCTGGAACCCGCTCGTAATATACCTGTACTGGCAACCACGGAAGTGTTAGTTGTTGGT
GGTGGTCCATCGGGTATTGCCGCAGCAATGAGTGCCGCTCGTGAAGGCGCAGCTACTATGCTGATTGAAC
GTTTCGGTTGTTTTGGCGGAATGATGACAACGGCTGGCGTCGAGTCAATTGCCTGGTGGCGTCATGAAAA
TACGGTAGAGTCAGGTGGACTGGCACGCGAAATAGAAGAAACGGCAAAATCAATGGGGGCGTCCAGCCCT
GAGCCGCAATCGAATAGTCAGGCTATTAACGCCGAGCGTTTCAAACTGGTTGCGGATGCAATGCTTGAAC
AGGCAGGTGTGCGCCGCGTACTACACATTACCGCCGTTGATGTTATCAAGCAGGGCAATAATTTACTCGG
CGTAATAACAGAGAGTAAATCTGGTCGTCAGGCTATTTTGGCAAATGTCATTATTGACTGTACTGGTGAT
GCTGATATTGCATGGTTTGCCGGAGCACCATTTATTAAGCGTGAACGCGAAGAGCTAATGTGTATGACAA
CCGTTTTTAGTTGCGCAAATATAAATAAAAACGCGTTCATGCAAAATATTAATAGCACGGAACCTAAATA
TGGAGACTGGGGGGCGGATGAAGAAAATAAAAACTGGTCTTATGATGTTCATGAATCTTGTCGCGATATG
TTTAGCCCTTATCTGGGTAAAGTCTTTGCGAAAGGAAAGTCGGCAGGAATTATTCCAAAAGATGTGACGT
TAGGCGGTTCCTGGAGTACGGTCACCGAGTATGGTGATGCGAATTACTTGAACGTTGTCAGCATCCCTGC
CGTCGATTGTACGGATGTTTTTGACCTGACGCGTGCAGAAATAGAAGGCCGCAAGCAAGCCATGCAGGCG
ATTGAAGCGTTGCGTCAATTCCAGCCAGGATTTGAACAGGCACAATTAAAAAATTTCGGTATGACGGTGG
GAACAAGAGAATCAAGACATATTATTGGGCGAGTCCAGCTTACGGAAAATGATATTTGTAATGAGGGACG
TCATGCGGATTCAATAGGGGTATTCCCTGAGTTTATAGATGGAAATGGTCATCTTAAATTACCTCTTGAA
GCGAACTATTTTCAAATCCCTTATGGCGTAATGATTCCGCAGCAAGTTGAAAACCTGTTGGTTTGCGGAC
GGGCAATCGATGCAGATAATTTCGCCTATGCGACAATCCGTAATATGGGGTGTTGTATTGTCACTGGAGA
AGGTGCAGGGACTGCCGCTGCTATTGCCATTAAAAATAACACTACCGTTTCACAGGTAGATATTCAGACG
GTACAGGAACGCTTACAGCAAAATGGCGTAAAAGTCTTTTA
Protein Sequence 
>gi|91213983|ref|YP_543969.1| invasion protein IbeA [Escherichia coli UTI89] MEFYLEPARNIPVLATTEVLVVGGGPSGIAAAMSAAREGAATMLIERFGCFGGMMTTAGVESIAWWRHENTVESGGLAREIEETAKSMGASSPEPQSNSQAINAERFKLVADAMLEQAGVRRVLHITAVDVIKQGNNLLGVITESKSGRQAILANVIIDCTGDADIAWFAGAPFIKREREELMCMTTVFSCANINKNAFMQNINSTEPKYGDWGADEENKNWSYDVHESCRDMFSPYLGKVFAKGKSAGIIPKDVTLGGSWSTVTEYGDANYLNVVSIPAVDCTDVFDLTRAEIEGRKQAMQAIEALRQFQPGFEQAQLKNFGMTVGTRESRHIIGRVQLTENDICNEGRHADSIGVFPEFIDGNGHLKLPLEANYFQIPYGVMIPQQVENLLVCGRAIDADNFAYATIRNMGCCIVTGEGAGTAAAIAIKNNTTVSQVDIQTVQERLQQNGVKVF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion mutant was significantly less invasive in human brain microvascular endothelial cells (BMECs) than the parent strain (E. coli K1) (Huang et al., 2001).
References
Huang et al., 2001: Huang SH, Wan ZS, Chen YH, Jong AY, Kim KS. Further characterization of Escherichia coli brain microvascular endothelial cell invasion gene ibeA by deletion, complementation, and protein expression. The Journal of infectious diseases. 2001; 183(7); 1071-1078. [PubMed: 11237832].