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iroC from Escherichia coli UTI89

Victor ID 2076
Gene Name iroC from Escherichia coli UTI89
Sequence Strain (Species/Organism) Escherichia coli UTI89
NCBI Gene ID 3991367
NCBI Protein GI 91210150
Locus Tag UTI89_C1121
Protein Accession YP_540136.1
Other Database IDs UniProtKB-ID: Q1RDF9_ECOUT
UniRef100: UniRef100_Q8GH16
UniRef90: UniRef90_Q8GH16
UniRef50: UniRef50_Q6KD93
UniParc: UPI00000BFD7D
EMBL: CP000243
EMBL-CDS: ABE06605.1
RefSeq_NT: NC_007946.1
EnsemblGenome: EBESCG00000066906.
EnsemblGenome_TRS: EBESCT00000067859
EnsemblGenome_PRO: EBESCP00000065337
GenomeReviews: CP000243_GR
KEGG: eci:UTI89_C1121
eggNOG: COG1132
HOGENOM: HBG429047
OMA: TYYIAGI
ProtClustDB: CLSK894342
BioCyc: ECOL364106:UTI89_C1121-MONOMER
Taxonomy ID 364106
Gene Starting Position 1112787
Gene Ending Position 1116572
Gene Strand (Orientation) -
Protein Name IroC protein
DNA Sequence 
>gi|91209055:1112787-1116572 Escherichia coli UTI89, complete genome
ACTATCCCGGGGTTTCCTCCTTCATGTTGTGCTGGCGATGGAGAGCAGTACTGCTGACGCTGTCATGCCA
TAAGCGGGTATAGAGGCCGCCCGCAGATAACAGCTGTTCGTGGGTTCCGTATTCCGCAAGTAACCCCTTA
TCAATAACGGCAATCAGATCGCAGCGTTGCGCGGTGGTCAGACGATGTGCAACAATCAGCGCCGAGTGCT
TCCCGGCATGCACGACATCTGTTAACGATGACATCAGTCGTTCTTCGGATGTGCGATCCAGACATGACGT
GGCTTCGTCGAGCAGCAGGATGTGGGCATTCGCCAGTTGCGCGCGGGCCAGCGCAATCAACTGGCGCTGA
CCTGCGGGCAGATCGGCTCCGCCGTTATTCACCGGTGTCCGGAATCCCTGCGGCAGATTGCACACCATCT
CATACAGCCCTGCCCGCTGTGAGGCAATTTCAACGTCTTCATTGGTGGCGGATGGCCGTGAATAACGAAT
GTTTTCTGCAATATCACTACTAAACAGTGCTACATCCTGATCGACAAGCCCAATCTGGCGACGATACTCA
GTGAGCGAGGCATCATCGAGCATTTGCACACCGATTCTGATGTTGCCGTGCGTGGGGAAATACAACCCGG
CAATCAGCTTAATCAGCGTCGACTTACCCGCACCGCTGCGACCGACGACCGCGACAACCATTCCCTCAGG
GATCGTCAGGGTAAGTTTGTTCAGAGCTGGCTCGTGACTGTCGGGATAACTGAACGTGACCTCATCAAGA
TGCAGTGCACCGGTGACAGGGAGGACCGAAGAGGACCCGAGGTTCTCAGTGCCTTCTGTCGCCAGTAGTT
CATCAATATGTTTGCCGCTGGCTGTCGCCTGCTGCCAGGCGTCGACAATCCCTGATAACTGCTGCACTGG
CCCATAGAATTGCCCCAGCAACAGGAAGAAAGCCGCCAGTACCCCGGCAGTCATTTCTCCAGCGGCGACC
TGCGAAGCTCCCACTAACAGAACAGCGGCATAGGAGGCCTCGGTGCAGAATGTCAGGAACGGAAAATAGA
CTGCAAGGTATTTTTGTGCTCGCACACGGGTTGCGCGGAAACGCTCCGATAACGCGCGCAGCCGGGCGCC
CTCCAGTTCCTGCTGACCATGCGATTGCACGACACGCAGGCCAGAGACTTTTTCCTGCAGGGTGCTGTTG
ACTTTGCCTATTTCCAGCCGTGCCTGTGCATAAGCAGGGGTACTGAGGCGGCGATAAATCATGGTTGCCA
GTGCGGCCACTGGCACTGCGCTTAATGCCGTCAGCGCCAGGAACGGGTCGAGCCAGAACATGGTGGCGGC
GATTGCGAACATCGTCACCAGACTGGTGGCCGCACCGGCAAGGCCGTTTTGCAGAAAGCGGGCGAGAGAG
TCCACATCAACGGTCATGCGGGTAAGACGCGAATCGGCATGCTTTTCATGCCAGGGGAGTCCAAGACGCA
GCATATGGCCGAAGCTGCGCAAGCGCACCGAATGCTGAACTGATTCCGCCGCTCTGGCGGCGAAGACCGT
CTGCAGAGAATAACTGCACCAGCCCACAATGACCAGGCACAGGGCGAGCAGGGCACAGAGGCCGATGATC
GACATATCGCCTGCGGCGACACCGGAGTCAATGCCGTGCTGCAACAGTATCAGTACCCCTACGCCTGCCG
CAGAATCGAGTGCGATCAGCAGAGCGGCGATGACGAACATCCACGCCACAGGCTTCAGTAGTGACGTGAC
TTTGCGACCTTTACCGGCCAGCGCCTGCTGTACTGCATTTTCCGGTACGCGGGTCATACGGGCGACAAAA
CCTTTATCCCCCGTATCCGTTACATCGTCTTGTGTCGCTGGTTCAGCCGGCCACAATTCGTTGTGGCTAT
TGTGGGACGTGGCCAGAAAATCGCTGTCGCCGGTCATCAGTGCGCGGAACGCCGGACAGCGCGCTTCAAG
TTCTGCCGGGGTTCCGGTATCCACCATACGGCCCTTATCCAGCACCACAACCCGGCTGGCTAGCTGAAGT
GTTGAACGCCGTCGGGCAATCACCAGCAGCATATGCCCTTCGTCAGCATAGCGACCCAGCGCGGTATTAA
TCTCCGCTTCCGTAACAGCATCAACCGCTGAGGTAGTATCATCCAGGATTAACACGTCCGGTGCAGTAAT
GAGCGCCCGCGCCAGCGCTATTCGCTGCCTCTGCCCGCCGGAAAGATTCGTACCCCGTTCGGTTAACAGG
CTATCGAAGCCTTTCGGCAGGGCGTTAATAAAATCGCTGGCTCCTGCAGCAGCTGCCGCACGGCGAATGT
CGTCCGCCGTTGCCTGAGGGTGGCCATAGGCGATATTTTCCGCCACCGTACCGGCAAACAGAAAAGCATC
TTCAAATACGATGCCTACCCGGCGACGAAGCGCCTCCAGTCTGATATCGCGAAGATTTTGTCGGCCTTCG
CTGGTGTTGAGCCATATCTTTCCGGAGCAGGGATCATAAAAACGCGCCAGTAGCATCAACAGGGTCGATT
TTCCTGAACCCGATGCGCCCACCACCGCCACGGTTTCACCGGCGCGCAGGGAAAAGGAGATATTGCTGAG
GATATGTCTGTCGCCATGGTGGTAGTCAAAGCTCATATTCTCCAGTTCCAGTCCGACAACCTGACTGTTA
ATCGACTCCGTCCCGTCCTCCATCTGTGAACGGGTGTCGATCAGTGCAAACACCCGCTCCACGGACGCCT
GAGTGCGCTGTGCGATAACCAGAAACGATGCCAGTACGCGGGTTGGCCCGGTCAGCATCGCGAGGAAGCT
GGCGAATGCAACGAAGGTACCGAGATCGATCCGCCCGTGCATGACCGACCACCCGCCGTAGCACAGCAGG
ACGATTTGCCCGAGCACCGGTAGCGCCAGCATGGTGGCCCCAGGCATCGCCTGCGAGATAACCGCACCGA
TGCGTACACGCACAATCTGCCGCGACTGCCTATCGAGCCAGTGCGTTTCACGCATCTCTGCCACACAGGA
TTTTACCACTGAGATCTGTGCCAGCACCTCGCGTATATGTTCGGTGAGATTCGCCAGTTGGTCCGAGGCC
AGCCCGGTTTGCGCGAAGACCCTACGACGCGCACGAAGCGCGGTGATCGCCAGGCATACCAGTACGCACA
CGACGATAAGCGTCATGGCAGGGGACATCCACAGCATCACGGCAATGCCGGCAATGTAATAAGTGAACAC
TGCCAGCGGCACCGGGCACATCTGCAGCAGGGTATGCACCTGCTGCAGATCGCTGTTGGTCCGTGAAATC
ACCTGCCCGGTGCGCAGCGCATCCTGGCCTGCGCCGTCAAGTTTCTGAATACTGTCGAATACCCGTCCTC
TGAGGGTATGCTGCACCCAGAGTGAGAGCATCCCGGCATAACCACGGCGCACATAGTTACCGATGAAATC
AAAAAAAGCGATCAACAGTAACCCGCAGGCCAGCCACGGCAGGCGGGCCGGATTGCCCGCCAGTGCGTCA
TTCACAGCCTGTCTTGTCAGCAGTGGCGTCAGCGCAGCCAGCAAAATAGTCGATACTGACGCTACCACCA
CGATGACACTAAGTTTCTTACGTTCCCAGCACACGCGCGCCAGGCGAACTATCCATGACTGAGCCGGTGT
GGGAGTGTGATTCGCAGGCATTAAGCCTCCTCCGTCTGTAAAATACGATCCACTGGCCGGATCGTTCCGC
AAAAAAGCCAGCACGCTCCGGTCCCGCATTGTTATGGATGCATGACTCCTGGATGGGTGCTGGCATATGA
TTATCA
Protein Sequence 
>gi|91210150|ref|YP_540136.1| IroC protein [Escherichia coli UTI89] MIIICQHPSRSHASITMRDRSVLAFLRNDPASGSYFTDGGGLMPANHTPTPAQSWIVRLARVCWERKKLSVIVVVASVSTILLAALTPLLTRQAVNDALAGNPARLPWLACGLLLIAFFDFIGNYVRRGYAGMLSLWVQHTLRGRVFDSIQKLDGAGQDALRTGQVISRTNSDLQQVHTLLQMCPVPLAVFTYYIAGIAVMLWMSPAMTLIVVCVLVCLAITALRARRRVFAQTGLASDQLANLTEHIREVLAQISVVKSCVAEMRETHWLDRQSRQIVRVRIGAVISQAMPGATMLALPVLGQIVLLCYGGWSVMHGRIDLGTFVAFASFLAMLTGPTRVLASFLVIAQRTQASVERVFALIDTRSQMEDGTESINSQVVGLELENMSFDYHHGDRHILSNISFSLRAGETVAVVGASGSGKSTLLMLLARFYDPCSGKIWLNTSEGRQNLRDIRLEALRRRVGIVFEDAFLFAGTVAENIAYGHPQATADDIRRAAAAAGASDFINALPKGFDSLLTERGTNLSGGQRQRIALARALITAPDVLILDDTTSAVDAVTEAEINTALGRYADEGHMLLVIARRRSTLQLASRVVVLDKGRMVDTGTPAELEARCPAFRALMTGDSDFLATSHNSHNELWPAEPATQDDVTDTGDKGFVARMTRVPENAVQQALAGKGRKVTSLLKPVAWMFVIAALLIALDSAAGVGVLILLQHGIDSGVAAGDMSIIGLCALLALCLVIVGWCSYSLQTVFAARAAESVQHSVRLRSFGHMLRLGLPWHEKHADSRLTRMTVDVDSLARFLQNGLAGAATSLVTMFAIAATMFWLDPFLALTALSAVPVAALATMIYRRLSTPAYAQARLEIGKVNSTLQEKVSGLRVVQSHGQQELEGARLRALSERFRATRVRAQKYLAVYFPFLTFCTEASYAAVLLVGASQVAAGEMTAGVLAAFFLLLGQFYGPVQQLSGIVDAWQQATASGKHIDELLATEGTENLGSSSVLPVTGALHLDEVTFSYPDSHEPALNKLTLTIPEGMVVAVVGRSGAGKSTLIKLIAGLYFPTHGNIRIGVQMLDDASLTEYRRQIGLVDQDVALFSSDIAENIRYSRPSATNEDVEIASQRAGLYEMVCNLPQGFRTPVNNGGADLPAGQRQLIALARAQLANAHILLLDEATSCLDRTSEERLMSSLTDVVHAGKHSALIVAHRLTTAQRCDLIAVIDKGLLAEYGTHEQLLSAGGLYTRLWHDSVSSTALHRQHNMKEETPG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in chicks (Caza et al., 2008).
COG COG1132V, under V: Defense mechanisms
References
Caza et al., 2008: Caza M, Lépine F, Milot S, Dozois CM. Specific roles of the iroBCDEN genes in virulence of an avian pathogenic Escherichia coli O78 strain and in production of salmochelins. Infection and immunity. 2008; 76(8); 3539-3549. [PubMed: 18541653].