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iroN from Escherichia coli UTI89

Victor ID 2074
Gene Name iroN from Escherichia coli UTI89
Sequence Strain (Species/Organism) Escherichia coli UTI89
NCBI Gene ID 3991364
NCBI Protein GI 91210147
Locus Tag UTI89_C1118
Protein Accession YP_540133.1
Other Database IDs UniProtKB-ID: Q1RDG2_ECOUT
UniRef100: UniRef100_Q8GH18
UniRef90: UniRef90_Q93K73
UniRef50: UniRef50_Q05098
UniParc: UPI00000BFD7B
EMBL: CP000243
EMBL-CDS: ABE06602.1
RefSeq_NT: NC_007946.1
EnsemblGenome: EBESCG00000068391.
EnsemblGenome_TRS: EBESCT00000069344
EnsemblGenome_PRO: EBESCP00000066822
GenomeReviews: CP000243_GR
KEGG: eci:UTI89_C1118
eggNOG: COG4771
HOGENOM: HBG464298
OMA: TMVVEST
ProtClustDB: PRK13528
BioCyc: ECOL364106:UTI89_C1118-MONOMER
Taxonomy ID 364106
Gene Starting Position 1108191
Gene Ending Position 1110368
Gene Strand (Orientation) +
Protein Name IroN protein
DNA Sequence 
>gi|91209055:1108191-1110368 Escherichia coli UTI89, complete genome
TATGAGAATTAACAAAATCCTCTGGTCGCTAACTGTGCTCCTGGTTGGGTTGAATAGCCAGGTATCAGTA
GCCAAATCCTCCGACGATGATAATGACGAGACTCTGGTGGTGGAAGCCACCGCTGAGCAGGTATTAAAAC
AGCAGCCGGGCGTGTCGGTTATTACCAGCGAGGATATTAAAAAGACCCCTCCGGTAAACGACCTTTCAGA
TATTATTCGTAAAATGCCTGGCGTCAATCTTACCGGCAATAGCGCCTCGGGCACACGCGGTAACAACCGC
CAGATCGATATTCGTGGTATGGGGCCGGAAAACACCTTAATTTTAATTGATGGTGTACCGGTGACGTCAC
GTAACTCCGTGCGTTATAGCTGGCGTGGAGAGCGTGATACCCGCGGTGACACCAACTGGGTGCCACCGGA
ACAGGTTGAGCGTATTGAAGTGATCCGCGGCCCTGCGGCGGCGCGCTACGGTTCGGGGGCAGCCGGGGGG
GTGGTGAACATCATTACCAAACGTCCCACCAACGACTGGCACGGTTCGCTGTCGTTATACACCAATCAGC
CGGAAAGTAGCGATGAGGGCGCTACGCGTCGCGCCAATTTCAGCCTTAGTGGGCCTCTGGCTGGTAATGC
TCTTACCACGCGTTTGTATGGTAATCTGAATAAAACGGATGCTGACAGTTGGGATATTAATTCTCCGGTC
GGTACGAAAAACGCAGCCGGGCATGAAGGGGTACGTAACAAAGATATTAACGGCGTTGTCTCGTGGAAAT
TAAATCCGCAGCAGATTCTCGATTTCGAAGCCGGATATAGCCGCCAGGGGAATATCTATGCGGGCGATAC
GCAAAACAGTTCTTCCAGTGCAGTTACCGAAAGCCTGGCAAAATCCGGCAAAGAGACGAACCGCCTGTAC
CGACAGAATTATGGCATTACGCATAATGGTATCTGGGACTGGGGACAAAGTCGCTTTGGTGTTTATTACG
AGAAAACCAATAATACCCGCATGAATGAAGGATTATCCGGCGGTGGTGAAGGGCGTATTTTAGCGGGTGA
AAAGTTTACGACCAATCGCCTGAGTTCCTGGCGAACCAGCGGCGAGCTTAATATTCCTTTGAATGTGATG
GTTGATCAAACGCTGACCGTTGGTGCAGAGTGGAACCGCGATAAGCTCGATGATCCTTCCTCTACCAGCC
TGACGGTGAATGACAGTGATATCAGCGGTATTTCTGGCTCTGCTGCGGATCGCAGCAGTAAAAATCATTC
TCAAATCAGTGCGCTGTATATTGAAGATAACATTGAGCCGGTTCCTGGCACGAATATCATTCCCGGCCTG
CGCTTTGATTATCTCAGCGACTCCGGCGGGAACTTCAGCCCCAGTCTGAATCTTTCGCAGGAATTGGGCG
ATTATTTCAAAGTCAAAGCAGGGGTTGCCCGAACCTTTAAAGCCCCAAACCTGTATCAATCCAGTGAAGG
CTATCTGCTCTACTCGAAAGGCAATGGCTGTCCAAAAGATATTACATCAGGCGGGTGCTACCTGATCGGT
AATAAAGATCTCGATCCGGAAATCAGCGTCAATAAAGAAATTGGGCTGGAGTTCACCTGGGAAGATTACC
ACGCAAGTGTGACCTACTTCCGCAATGATTACCAGAATAAGATCGTGGCCGGGGATAACGTTATCGGGCA
AACCGCTTCAGGCGCATATATCCTCAAGTGGCAGAATGGCGGGAAAGCTCTGGTGGACGGTATCGAAGCC
AGTATGTCTTTCCCACTGGTGAAAGATCGTCTGAACTGGAATACCAATGCCACATGGATGATCACTTCGG
AGCAAAAAGACACCGGTAATCCTCTGTCGGTCATCCCGAAATATACTATCAATAACTCGCTTAACTGGAC
CATCACCCAGGCGTTTTCTGCCAGCGTCAACTGGACGTTATATGGCAGACAAAAACCGCGTACTCATGCG
GAAACCCGCAGTGAAGATACTGGCGGTCTGTCAGGTAAAGAGCTGGGCGCTTATTCACTGGTGGGGACGA
ACTTCAATTACGATATTAATAAAAATCTGCGTCTTAATGTCGGCGTCAGTAATATCCTCAATAAACAGAT
CTTCCGATCTTCTGAAGGGGCGAATACCTATAACGAGCCAGGCCGGGCTTACTATGCCGGAGTTACCGCA
TCATTCTG
Protein Sequence 
>gi|91210147|ref|YP_540133.1| outer membrane receptor FepA [Escherichia coli UTI89] MRINKILWSLTVLLVGLNSQVSVAKSSDDDNDETLVVEATAEQVLKQQPGVSVITSEDIKKTPPVNDLSDIIRKMPGVNLTGNSASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAAGGVVNIITKRPTNDWHGSLSLYTNQPESSDEGATRRANFSLSGPLAGNALTTRLYGNLNKTDADSWDINSPVGTKNAAGHEGVRNKDINGVVSWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGKETNRLYRQNYGITHNGIWDWGQSRFGVYYEKTNNTRMNEGLSGGGEGRILAGEKFTTNRLSSWRTSGELNIPLNVMVDQTLTVGAEWNRDKLDDPSSTSLTVNDSDISGISGSAADRSSKNHSQISALYIEDNIEPVPGTNIIPGLRFDYLSDSGGNFSPSLNLSQELGDYFKVKAGVARTFKAPNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKDLDPEISVNKEIGLEFTWEDYHASVTYFRNDYQNKIVAGDNVIGQTASGAYILKWQNGGKALVDGIEASMSFPLVKDRLNWNTNATWMITSEQKDTGNPLSVIPKYTINNSLNWTITQAFSASVNWTLYGRQKPRTHAETRSEDTGGLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNILNKQIFRSSEGANTYNEPGRAYYAGVTASF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iroA gene cluster mutants were unable to resist Lcn2 in mouse serum (Fischbach et al., 2006).
COG COG4771P, under P: Inorganic ion transport and metabolism
References
Fischbach et al., 2006: Fischbach MA, Lin H, Zhou L, Yu Y, Abergel RJ, Liu DR, Raymond KN, Wanner BL, Strong RK, Walsh CT, Aderem A, Smith KD. The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(44); 16502-16507. [PubMed: 17060628].