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hlyA from Escherichia coli UTI89

Victor ID 2071
Gene Name hlyA from Escherichia coli UTI89
Sequence Strain (Species/Organism) Escherichia coli UTI89
NCBI Gene ID 3990775
NCBI Protein GI 91213874
Locus Tag UTI89_C4926
Protein Accession YP_543860.1
Other Database IDs UniProtKB-ID: Q1R2T5_ECOUT
UniRef100: UniRef100_Q1R2T5
UniRef90: UniRef90_P08715
UniRef50: UniRef50_P08715
UniParc: UPI0000D50EDA
EMBL: CP000243
EMBL-CDS: ABE10329.1
RefSeq_NT: NC_007946.1
EnsemblGenome: EBESCG00000069572.
EnsemblGenome_TRS: EBESCT00000070525
EnsemblGenome_PRO: EBESCP00000068003
GenomeReviews: CP000243_GR
KEGG: eci:UTI89_C4926
eggNOG: COG2931
HOGENOM: HBG296556
OMA: DTAASIN
ProtClustDB: CLSK862058
BioCyc: ECOL364106:UTI89_C4926-MONOMER
Taxonomy ID 364106
Gene Starting Position 4825021
Gene Ending Position 4828095
Gene Strand (Orientation) -
Protein Name hemolysin A
DNA Sequence 
>gi|91209055:4825021-4828095 Escherichia coli UTI89, complete genome
ATTATGCTGATGCTGTCAAAGTTATTGAGTTCCGTCCATATGAAAAATCACTGGCATTACCGGACAACTG
CAATAAAGAAGCGGCAGATCTTTCCTCCTTAACATCGAAGTTACCTGCAGCTGAAATGATTTTGCTGATT
TCATTAATTAATGGATTAAGATTGTCCTGGCTCCCATAAGTTGATGCATCATGTCCATACACATAACTTA
CCTTGTTATTACTCTGCTGATATTCAAATGCTTTTTTAAGAGAATCTGGTGTGATTACCCTGCCGTCTTT
ATCAAAAATCTGCTCTATCTGATGATTAGAGAGATCATCTGACTCTTTTTCAAACCAGTTTTTAAATGTA
ATACCATTTTTGTGGCCAATAGAAAGAACATTACCTTCAGCTTTATACATAATGAGGTCATTCCCTTCTC
GCTTAAAGGCAACGTCCCGGAAATCTATATCAGCTAAACTGAGTTTATCGTCTTTCCCCCCTTCATCGTC
AATAATATGATGGCCATATCCTGAAAGATAACGATAAATATCATTACCATATCCACCTTTCAGAAGATCA
TTCCCTTCTCCGCCATCAAGCAGGTCTGCTCCCTCACTGCCGTACAACTTGTCATTACCTTTTCCACCGG
ATAATACATTTTTAGCAAGAGAATTCCCCTGAACCTGAAGCTCATCATCTCCGTCACCGCCGTTAAGGTA
ATTATTACCTGTCCCCCCAATTAACTTATCATTGCCATCACCGCCATAGAGCTGGTCATCCCCGTTTCCG
CCCCTCAGCGTATCATTACCTTTATCACCATATAAGCGGTCATTCCCATCATTTCCTTCTATATGGTCAT
CACCATCCGCGCCATGGAAGATATCAGTAAATTTACTGCCAAAAAACTTGTCGGCACGCGTGGTCCCAAT
AAGTTCTTCCACGGAATATAAGTTATCTGTCTCTGTTAAATTTTTACCATTGATATGAGTGAATTCATAA
CTCCGATATTGCGTTTTTTCAGTTCTTTTTCCGACTGAAACCTCCTGCTCCTTCACAACTTCCTGTAAAA
CCTTAACATCACCACCAAGTACACGTGTTACCGTGTAATTACCCGCTTCGGTTGCTTTTGTGCCATCAAT
GGTCAGATAACCGGTGTCTGTTTTATCATAATAAACAACATCATGTCCTTTACCTGCGTAGATATTGGCT
GAGCCGGCAGATAAAAAGACCTTATCATCCCCGTCTCCCAGGTGTGACTCAATACGAATTTCCCGATACT
GGTTATTACCGACTGATGCATGCTGAATCAGGTTAGAGTAATCATATACAGACCCCTTGTCCTGAACCCC
CTTCACCGTCCATTTATCAACACCCTTGACTAATAACTCGGTAATATATTCATATTTTCCGGACTGCCTC
CTTTCACGAATTTCCTCACCGGGAGTTAACAATGGCGTAACAAATTTCAATAACGTAGAAGATTTGCTGT
CAGAAAGGTCAATATTTCCTTTTAATGGATCAAAGATTTGTTGCTGGAACTCTTTTGGCCTTCTTTCCAG
CCGCTTTCCCTCTTCATAATAGTCAATATAACTTTTACCACTGAGTGTCTTGTCTCCATTTCTGGTGACA
CTAGCTAACTCACCTATCAGCATATCCCAATGTTGTTGAGTAATGAGGACTGATCTTTCAACAGAATACT
CTTTATTATACTGAGATAATATTTTAAAGTTATCTTCTAAAAATGCAGCATGGCGGGCATCATATCCATT
TTCAAAGTAATTTTTACCGTGTTTTTTCTCCCATTCAGCAATAACATCAGCCATTTTACTGGCAACATGT
TCAAACATTGCCTGCTTTGAAGCCTCAAGGATACCTGAAATTATCCCCGTAACAGCACCTACCAGTGCGC
TTACCGGTGCACCAACAAGAGATGTCGTTGCAGCAGCACTAATACCTGAAGATACTGAAGCCAGTACAGT
GCTTATCGTTGTTAATGATGCATCAATAGCTCCTGTTTCTTTGTGGAAAGCAGCAAGTAAACTGTCACCA
TCGTATCCAAGTTTTTTGAATCGTTGTGAATACTCCTCTATTTTATTTGCACGTTTAAACTTATCGGCAA
TGGACAGGAATGAGAGGGGACTAATTGCTAATGTCACTACAGAAGCAATTAAACCGGCAGCAGCAGCAGA
TGTAGATAACCCCTGTGCAGCGCGCTGTGCGATAATATATTGAGAAATACCTTTTCCAACATTACCCAGT
ACTTTCGTTGTTAATTCAACACCTGCTGCAGCTTTAGTTCCGGTATCTGCATCTGCATTGCTCAGAATGA
AGCTTGCTGAAATCGCAGATAAAATACCCGATACAGTATCTAACCCTGCACCGATATTATCAAGGTTAGG
TAAATTCTGTAACTTATTACCAACACCGTTCAGGTGCTTTGTATTGGATAATACACTTCCCAGCTTATTG
AGTTGTTGAGAAAATGAGTTAACATTATTATTAATGCTGGCAGCTGTGTCCACGAGTTGGTTGATTAGCT
CAATACTCGCTTTTGCCAGTTCAGAAGAACTGACATTGCTACCAGATTTTTGTTTCTTTATCAGTTCGTC
TATTTTCATTGAGGAAAGTGCAGTACCCAGAAAATTTTGAAACGTTGACAGTACACTGCCTGCCTTTCCT
AAGTTATCACCTATATTTTCAGCACTGCCGCCTAATTTATTACCCGCTTTTTGATACTTTTGCAGTAATT
TGTCTAATTGTGGTGCAAAGATAGTCACTCCCCGTTCGGTGAGGCCAATGAGTTTCTCTGCTGTGCCGAA
TACCTGTTTAGTAATCGCCGTGCCATTCTTTTCATCATACTGGACTTCAATTCCCAGTTCATCTGCCGTC
CTGACAAGGTCATTAAGGCTTGAACCCTGTCCTTTATAATCTTTAGGGATAAGTAAAATGAGTCTGTTTC
CCGCATTGCGGGTTTGCTCTGCTGCTTTTTTTAATGCATCTTTCGTGCTTTGTCCTGCTGAGTGCAATTT
ATTTGCAGCGGATTGCTTTGCAGACTGTAGTGTGCTTTTAATTTGTGCAGTGGTTATTGTTGGCA
Protein Sequence 
>gi|91213874|ref|YP_543860.1| hemolysin A [Escherichia coli UTI89] MPTITTAQIKSTLQSAKQSAANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQGSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGNKLGGSAENIGDNLGKAGSVLSTFQNFLGTALSSMKIDELIKKQKSGSNVSSSELAKASIELINQLVDTAASINNNVNSFSQQLNKLGSVLSNTKHLNGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADTGTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDMLIGELASVTRNGDKTLSGKSYIDYYEEGKRLERRPKEFQQQIFDPLKGNIDLSDSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGSVYDYSNLIQHASVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIFHGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGDGNDKLIGGTGNNYLNGGDGDDELQVQGNSLAKNVLSGGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDIYRYLSGYGHHIIDDEGGKDDKLSLADIDFRDVAFKREGNDLIMYKAEGNVLSIGHKNGITFKNWFEKESDDLSNHQIEQIFDKDGRVITPDSLKKAFEYQQSNNKVSYVYGHDASTYGSQDNLNPLINEISKIISAAGNFDVKEERSAASLLQLSGNASDFSYGRNSITLTASA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in zebra fish (Wiles et al., 2009).
COG COG2931Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Wiles et al., 2009: Wiles TJ, Bower JM, Redd MJ, Mulvey MA. Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli. PLoS pathogens. 2009; 5(12); e1000697. [PubMed: 20019794].