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dppA from Escherichia coli UTI89

Victor ID 2069
Gene Name dppA from Escherichia coli UTI89
Sequence Strain (Species/Organism) Escherichia coli UTI89
NCBI Gene ID 3989640
NCBI Protein GI 91213056
Locus Tag UTI89_C4082
Protein Accession YP_543042.1
Other Database IDs UniProtKB-ID: Q1R553_ECOUT
UniRef100: UniRef100_E2QGQ2
UniRef90: UniRef90_P23847
UniRef50: UniRef50_P23847
UniParc: UPI00000E4A94
EMBL: CP000243
EMBL-CDS: ABE09511.1
RefSeq_NT: NC_007946.1
EnsemblGenome: EBESCG00000065581.
EnsemblGenome_TRS: EBESCT00000066534
EnsemblGenome_PRO: EBESCP00000064012
GenomeReviews: CP000243_GR
KEGG: eci:UTI89_C4082
eggNOG: COG0747
HOGENOM: HBG688042
OMA: TVELWAM
ProtClustDB: CLSK880713
BioCyc: ECOL364106:UTI89_C4082-MONOMER
Taxonomy ID 364106
Gene Starting Position 3973523
Gene Ending Position 3975130
Gene Strand (Orientation) -
Protein Name periplasmic dipeptide transport protein precursor
DNA Sequence 
>gi|91209055:3973523-3975130 Escherichia coli UTI89, complete genome
ATTATTCGATAGAGACATTTTCGAAGTGATGTTTGCCTAATGGATCAACCACATAGCCTTTAACTTCTTT
GCGTACCGGTTCAAACACGGTGGAGTGAGCGATGATCAGTGCCGGAGCCTGATCGTGCATCACGACCTGT
GCTTGTTTGTACAGTTCAACACGTTTATTGTGGTCGTCGGTAGCACGCGCCGGTTGAATCAGATCTTCAA
ACGGTTTGTAGCACCATTTTGAGTAGTTGGAGCCTTGTTCAGAGGCGGCGCAGCTGAACAGGGTGGCGAA
GAAGTTATCCGGATCCCCGTTATCGCCAGTCCAGCCCATCATTACCGTCTGATGCTCGCCATCTTTCGCA
CGCTTGAGGTACTCACCCCATTCGTAGGTGACGATTTTGGCCTGCACGCCCACTTTCGCCCAGTCTGCCT
GAATCATCTCCGCCATGCGGCGAGCATTCGGGTTATACGGACGTTGTACCGGCATTGCCCACAGGTCGAT
GGAGAAACCTTTTTCCAGACCCGCTTCTTTCAGCAAGGCTTTCGCTTTTTCAGGATCGTAAGTGTAGTCC
TGAACGTCGTCGTTATAGCCCCACATGGTTGGCGGGATCAGGTTTTTCGCTGATACGCCCGCGCCCTGAT
AAACCGCTTTGATGATAGCGTCTTTGTTCACCGCGTAGGTCAGAGCCTGGCGAACTTTCACGTCATCCAG
TGGTTTTTTCTGCACGTTATACGAGAGATAACCGACGTTCAGCCCCGGCATTTCCATCAGGTTGATGGAT
TTATCCTGCTTCATGCGGGCGATATCTGCCGGGTTCGGGTACGGCATCACCTGGCATTCGTTCTTCTGCA
ATTTCGCGTAACGCACGGAAGCGTCAGGAGTAATAGAGAAGACCAGCGTATCGATCTTCGGTTTGGTGCC
CCAGTAGCCATCAAACGCTTTATAGCGAATACGGGAATCTTTCTGGTACTGCTGTAACTGGAACGGGCCG
GTACCGATTGGGTTGAGGTCCAGTTTTTCCGGTGTACCGGCTTTCATCATCGCGTCAGCATATTCTTTTG
ACAGAATAGAGGCGAAGTCCATTGCCAGGTCAGCGAGGAACGGCGCTTCCGGGCGAGTCAGCACAAACTG
AACGGTGTTATCGTCCACCTTTTTCACTTCGCTGATCAGCTCTGGTAAGCCCATGCCTTCGAAGTATTCG
TAGCTGCCGCCAGAGACTTTATGGTACGGGTTTTGCGCGTTTTTCTGACGATCGAACGAGAACACTACGT
CATCGGCATTCAGTTCGCGCGTCGGTTTGAATTCTTTATTGTCGTGCCACTTCACACCTTTACGCAGATG
GAAGGTATAGGTTTTACCGTCTTCGCTGACTTCCCACTTTTCAGCGAGGCCCGGGATCACTTCAGTGGTG
CCGATTTTAAATTCAACCAGACGGTTATAAAGCGGTACGGAAGAGGCGTCATAGGTGGTGCCGGAGGTAA
ACAGCTGCGGGTTAAACCCTTCCGGAGATCCTTCTGAGCAATAAACCAGAGTTTTAGCCTGAACACTTGC
TGCGACGGTCATAGCCACCAGGCTGAGACCAAGCTTCAGCATCCCTGACTTTTTCAAGGAAATACGCA
Protein Sequence 
>gi|91213056|ref|YP_543042.1| periplasmic dipeptide transport protein [Escherichia coli UTI89] MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPKIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dppA mutant was attenuated 10- to 50-fold compared to the wild type for colonization of the bladders and kidneys of mice (Haugen et al., 2007).
COG COG0747E, under E: Amino acid transport and metabolism
References
Haugen et al., 2007: Haugen BJ, Pellett S, Redford P, Hamilton HL, Roesch PL, Welch RA. In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infection and immunity. 2007; 75(1); 278-289. [PubMed: 17074858].