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ompA from Escherichia coli APEC O1

Victor ID 2055
Gene Name ompA from Escherichia coli APEC O1
Sequence Strain (Species/Organism) Escherichia coli APEC O1
NCBI Gene ID 4493784
NCBI Protein GI 117623167
Locus Tag APECO1_62
Protein Accession YP_852080.1
Other Database IDs UniProtKB-ID: A1A9M6_ECOK1
UniRef100: UniRef100_A1A9M6
UniRef90: UniRef90_B7LNW7
UniRef50: UniRef50_B7LNW7
UniParc: UPI0000E44F22
EMBL: CP000468
EMBL-CDS: ABJ00366.1
RefSeq_NT: NC_008563.1
EnsemblGenome: EBESCG00000034581.
EnsemblGenome_TRS: EBESCT00000035531
EnsemblGenome_PRO: EBESCP00000034048
GenomeReviews: CP000468_GR
KEGG: ecv:APECO1_62
eggNOG: COG2885
HOGENOM: HBG741096
OMA: DDNEAQK
ProtClustDB: PRK10808
BioCyc: ECOL405955:APECO1_62-MONOMER
Taxonomy ID 405955
Gene Starting Position 1015301
Gene Ending Position 1016413
Gene Strand (Orientation) -
Protein Name outer membrane protein A
DNA Sequence 
>gi|117622295:1015301-1016413 Escherichia coli APEC O1, complete genome
CTTAAGCCTGCGGCTGAGTTACAACGTCTTTGATGCCTTTAACTTCGATCTCTACGCGACGATCCGGAGC
CAGGCAATCGATCAGTGCAGCACGCTGTTTCACGTTGTCACAGGTGTTGCCAGTAACCGGGTTGGATTCG
CCCATACCACGTGCGGAGATTTTGTCTGCCGGGATACCTTTAGAGATCAGGTAATCAACAACGGACTGAG
CACGACGCTCGGACAGAGCCTGGTTATAAGCGTCAGAACCGATGCGGTCAGTGTAACCCAGAACAACTAC
GGAACCGTCTTTCGGATCCAGGTTGCTCAGCTGGCTGTACAGCTGATCCAGAGCAGCCTGACCTTCCGGT
TTCAGGGTTGCTTTGTTGAAGGTGAACAGAACGTCAGACTTCAGAGTGAAGTGCTTGGTCTGTACTTCCG
GTGCCGGAGCTGGAGCCGGAGCAACTACTGGAGCTGCTTCGCCCTGACCGAAACGGTAGGAAACACCCAG
GCTCAGCATGCCGTTGTCCGGACGAGTGCCGATGGTGTGTGCGTCACCGATGTTGTTGGTCCACTGGTAT
TCCAGACGGGTAGCGATTTCAGGAGTGATCGCATACTCAACACCGCCAGCGAAGACCGGAGAAACGCCGG
TGTCGTGGTTTTTACCATAAACGTTGGATTTAGTGTCTGCACGCCATACCATACCACCCAGACGAGTGTA
TACGTCCAGATCGTCAGTGATTGGGTAACCCAGTTTAGCGGTCAGCTGAACGCCCTGAGCTTTATATGCA
CCGTTTTCAACGCTGCCTTTGTATGGCATACGACCTAACCAGTCATAACCCATTTCAAAGCCAACATACG
GGTTAACCTGGTAACCACCAAAAGCACCAGCGCCCAGTTGGTTTTCATGGGTCGGACCATTGTTGTTGAT
GAAACCAGTGTCATGGTACTGGGACCAGCCCAGTTTAGCACCAGTGTACCAGGTGTTATCTTTCGGAGCG
GCCTGCGCTACGGTAGCGAAACCAGCCAGTGCCACTGCAATCGCGATAGCTGTCTTTTTCATTTTTTGCG
CCTCGTTATCATCCAAAATACGCCATGAATATCTCCAACGAGATAACACGGTTAAATCCTTCA
Protein Sequence 
>gi|117623167|ref|YP_852080.1| outer membrane protein A [Escherichia coli APEC O1] MKDLTVLSRWRYSWRILDDNEAQKMKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFTFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQALSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: OmpA− strains are unable to cause actin condensation needed for invasion of brain epithelial cells (Prasadarao et al., 1999).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Prasadarao et al., 1999: Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS. Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infection and immunity. 1999; 67(11); 5775-5783. [PubMed: 10531228].