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malX

Victor ID 2054
Gene Name malX
Sequence Strain (Species/Organism) Escherichia coli APEC O1
NCBI Gene ID 4493654
NCBI Protein GI 117623807
Locus Tag APECO1_704
Genbank Accession CP000468
Protein Accession YP_852720
Other Database IDs UniProtKB-ID: A1ABG6_ECOK1
UniRef100: UniRef100_A1ABG6
UniRef90: UniRef90_P19642
UniRef50: UniRef50_P19642
UniParc: UPI0000E44FDC
EMBL: CP000468
EMBL-CDS: ABJ01006.1
RefSeq_NT: NC_008563.1
EnsemblGenome: EBESCG00000036675.
EnsemblGenome_TRS: EBESCT00000037625
EnsemblGenome_PRO: EBESCP00000036142
GenomeReviews: CP000468_GR
KEGG: ecv:APECO1_704
eggNOG: COG1263
HOGENOM: HBG571563
OMA: IFGTGER
ProtClustDB: PRK10110
BioCyc: ECOL405955:APECO1_704-MONOMER
Taxonomy ID 405955
Gene Starting Position 1720838
Gene Ending Position 1722430
Gene Strand (Orientation) +
Protein Name bifunctional PTS system maltose and glucose-specific transporter subunits IICB
Protein pI 8.49
Protein Weight 51724.73
Protein Length 530
Protein Note phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site
DNA Sequence 
>gi|117622295:1720838-1722430 Escherichia coli APEC O1, complete genome
TATGACGGCGAAAACAGCACCGAAAGTCACGCTGTGGGAGTTCTTCCAGCAGTTAGGCAAAACCTTCATG
TTACCCGTGGCATTATTGTCGTTCTGCGGCATTATGCTCGGCATTGGTAGTTCTCTTAGCAGCCATGATG
TCATCACCCTGATCCCGGTCCTGGGCAACCCCGTGTTGCAGGCTATCTTTACCTGGATGAGTAAGATTGG
CTCGTTTGCTTTTAGTTTCCTGCCAGTCATGTTCTGTATCGCCATCCCGCTGGGTCTGGCACGCGAAAAC
AAAGGCGTAGCGGCATTCGCTGACTTCGTCGGTTATGCGGTAATGAACCTCGCGGTAAACTTCTGGTTGA
CCAATAAAGGCATTCTGCCAACCACGGACGCCGCAGTTCTGAAAGCCAATAACATCCAGAGCATTCTTGG
GATCCAGTCGATCGACACCGGGATCCTCGGTGCGGTGATCGCCGGTATTATCGTCTGGATGCTGCATGAG
CGATTCCATAATATCCGCCTGCCGGATGCGCTGGCATTCTTCGGCGGTACGCGCTTCGTACCAATCATCT
CCTCGCTAGTGATGGGTCTTGTCGGCCTGGTGATTCCATTAGTCTGGCCGATTTTCGCCATGGGTATTAG
CGGCTTAGGCCATATGATCAACAGCGCGGGAGATTTCGGACCGATGCTGTTTGGTACCGGTGAACGTCTG
CTGTTGCCGTTTGGTCTGCATCACATTCTGGTGGCATTAATTCGCTTTACCGACGCAGGCGGCACGCAGG
AAGTCTGCGGTCAAACCGTCAGCGGTGCACTGACCATCTTCCAGGCGCAATTGAGTTGCCCAACCACTCA
CGGTTTTTCTGAAAGCGCCACGCGTTTCCTTTCGCAAGGTAAAATGCCTGCGTTTCTCGGCGGTCTGCCA
GGTGCAGCGTTAGCTATGTATCACTGTGCGCGCCCGGAAAATCGCCATAAAATTAAAGGTCTGCTGATTT
CTGGCCTGATCGCCTGTGTCGTTGGCGGCACGACCGAACCGCTGGAATTCCTGTTCCTGTTCGTAGCGCC
AGTTCTGTATGTCATCCACGCGCTGTTAACCGGCCTCGGCTTCACTGTCATGTCTGTGCTCGGCGTCACC
ATCGGTAATACCGACGGCAATATCATCGACTTTGTGGTGTTCGGTATTTTGCATGGTCTGTCAACCAAGT
GGTACATGGTGCCAGTAGTGGCGGCAATCTGGTTTGTCGTTTACTACATCATCTTCCGTTTCGCTATCAC
CCGCTTCAATCTCAAAACCCCGGGGCGCGATAGTGAAGTTGCCAGTTCAATCGAAAAAGCCGTTGCCGGT
GCGCCGGGTAAATCAGGTTACAACGTTCCGGCAATCCTCGAAGCCTTAGGCGGTGCCGACAATATTGTCA
GCCTCGATAACTGCATTACGCGTCTGCGTTTGTCTGTAAAAGATATGTCGCTTGTTAATGTGCAGGCACT
GAAGGACAATCGGGCAATTGGCGTAGTACAACTTAATCAACATAACCTGCAGGTTGTTATCGGGCCACAA
GTTCAGTCAGTAAAAGATGAAATGGCCGGTCTGATGCATACTGTCCAGGCATA
Protein Sequence 
>gi|117623807|ref|YP_852720.1| bifunctional maltose and glucose-specific PTS system components IICB [Escherichia coli APEC O1]
MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLIPVLGNPVLQAIFTWMSKIG
SFAFSFLPVMFCIAIPLGLARENKGVAAFADFVGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILG
IQSIDTGILGAVIAGIIVWMLHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGIS
GLGHMINSAGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSCPTTH
GFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVVGGTTEPLEFLFLFVAP
VLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMVPVVAAIWFVVYYIIFRFAIT
RFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQAL
KDNRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: malX mutant is attenuated in chickens (Li et al., 2005).
COG COG1263G, under G: Carbohydrate transport and metabolism
References
Li et al., 2005: Li G, Laturnus C, Ewers C, Wieler LH. Identification of genes required for avian Escherichia coli septicemia by signature-tagged mutagenesis. Infection and immunity. 2005; 73(5); 2818-2827. [PubMed: 15845486].