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ompA from Escherichia coli E24377A

Victor ID 2035
Gene Name ompA from Escherichia coli E24377A
Sequence Strain (Species/Organism) Escherichia coli E24377A
NCBI Gene ID 5589214
NCBI Protein GI 157159269
Locus Tag EcE24377A_1071
Protein Accession YP_001462189.1
Other Database IDs UniProtKB-ID: A7ZK60_ECO24
UniRef100: UniRef100_Q49P72
UniRef90: UniRef90_B7LNW7
UniRef50: UniRef50_B7LNW7
UniParc: UPI000057487D
EMBL: CP000800
EMBL-CDS: ABV21007.1
RefSeq_NT: NC_009801.1
EnsemblGenome: EBESCG00000019587.
EnsemblGenome_TRS: EBESCT00000020533
EnsemblGenome_PRO: EBESCP00000019595
GenomeReviews: CP000800_GR
KEGG: ecw:EcE24377A_1071
NMPDR: fig|331111.3.peg.3561
eggNOG: COG2885
HOGENOM: HBG741096
OMA: DDNEAQK
ProtClustDB: PRK10808
BioCyc: ECOL331111:ECE24377A_1071-MONOMER
Taxonomy ID 331111
Gene Starting Position 1097661
Gene Ending Position 1098713
Gene Strand (Orientation) -
Protein Name outer membrane protein A
DNA Sequence 
>gi|157154711:1097661-1098713 Escherichia coli E24377A, complete genome
CTTAAGCCTGCGGCTGAGTTACAACGTCTTTGATGCCTTTAACTTCGATCTCTACGCGACGATCCGGAGC
CAGGCAGTCGATCAGTGCAGCACGCTGTTTCACGTTGTCACAGGTGTTGCCAGTAACCGGGTTGGATTCG
CCCATACCACGTGCGGAGATCTTGTCTGCCGGGATACCTTTGGAGATCAGGTAATCAACAACAGACTGAG
CACGGCGCTCGGACAGACCCTGGTTGTAAGCGTCAGAACCGATGCGGTCAGTGTAACCCAGAACAACTAC
GGAACCGTCTTTCGGATCCAGGTTGCTCAGCTGGCTGTACAGCTGATCCAGAGCAGCCTGACCTTCCGGT
TTCAGGGTTGCTTTGTTGAAGTTGAACAGAACGTCAGACTTCAGAGTGAAGTGCTTGGTCTGTACTTCCG
GTGCCGGAGCTGGAGCCGGAGCAACTACCGGAGCTGCTTCGCCCTGACCGAAACGGTAGGAAACACCCAG
GCTCAGCAGACCGTTGTCCGGACGAGTACCGATGGTGTTTGCGTCACCGATGTTGTTGGTCCACTGGTAT
TCCAGACGGGTAGCGATTTCAGGAGTGATCGCGTACTCAACACCACCTGCGAAAACCGGAGAAACGCCAG
TGTCGTGGTCTTTAAAGGATGCGCCACCAGGTACGTTAGCCTTGGTGTCTGCACGCCATACCATACCACC
CAGACGAGTGTATACGTCCAGATCGTCAGTGATTGGGTAACCCAGTTTAGCAGTCAGTTGAACGCCCTGA
GCTTTGTATGCTCCGTTGATGTTGTCGCCTTTGTACGGCATACGACCTAACCAGTCGTAACCCATTTCAA
AACCAACATACGGGTTAACCTGGTAACCACCAAAAGCACCTGCACCCAGTTGGTTTTCGTGGGTCGGACC
ATTGTTAGGAATAAAACCAGTGTCATGGTACTGGGACCAGCCCAGTTTAGCACCAGTGTACCAGGTGTTA
TCTTTCGGAGCGGCCTGCGCTACGGTAGCGAAACCAGCCAGTGCCACTGCAATCGCGATAGCTGTCTTTT
TCA
Protein Sequence 
>gi|157159269|ref|YP_001462189.1| outer membrane protein A [Escherichia coli E24377A] MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDANTIGTRPDNGLLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: OmpA− strains are unable to cause actin condensation needed for invasion of brain epithelial cells (Prasadarao et al., 1999).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Prasadarao et al., 1999: Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS. Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infection and immunity. 1999; 67(11); 5775-5783. [PubMed: 10531228].