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dppA from Escherichia coli E24377A

Victor ID 2033
Gene Name dppA from Escherichia coli E24377A
Sequence Strain (Species/Organism) Escherichia coli E24377A
NCBI Gene ID 5586739
NCBI Protein GI 157159059
Locus Tag EcE24377A_4037
Protein Accession YP_001465018.1
Other Database IDs UniProtKB-ID: A7ZT89_ECO24
UniRef100: UniRef100_P23847
UniRef90: UniRef90_P23847
UniRef50: UniRef50_P23847
UniParc: UPI0000129845
EMBL: CP000800
EMBL-CDS: ABV20797.1
RefSeq_NT: NC_009801.1
EnsemblGenome: EBESCG00000019868.
EnsemblGenome_TRS: EBESCT00000020814
EnsemblGenome_PRO: EBESCP00000019876
GenomeReviews: CP000800_GR
KEGG: ecw:EcE24377A_4037
eggNOG: COG0747
HOGENOM: HBG688042
OMA: TVELWAM
ProtClustDB: CLSK880713
BioCyc: ECOL331111:ECE24377A_4037-MONOMER
Taxonomy ID 331111
Gene Starting Position 4018926
Gene Ending Position 4020533
Gene Strand (Orientation) -
Protein Name dipeptide ABC transporter, periplasmic dipeptide-binding protein
DNA Sequence 
>gi|157154711:4018926-4020533 Escherichia coli E24377A, complete genome
ATTATTCGATAGAGACGTTTTCGAAGTGATGTTTGCCTAATGGATCAACCACATAGCCTTTGACTTCTTT
GCGTACCGGTTCAAACACGGTGGAGTGAGCGATGATCAGTGCCGGAGCCTGATCGTGCATCACCACCTGC
GCTTGCTTGTACAGTTCAACGCGTTTGTTATGGTCGTCGGTAGCACGCGCCGGTTGAATCAGATCTTCAA
ACGGTTTGTAGCACCATTTTGAGTAGTTAGAACCTTGTTCAGAGGCGGCGCAGCTGAACAGGGTGGCGAA
GAAGTTATCCGGGTCCCCGTTATCGCCAGTCCAGCCCATCATTACCGTCTGATGTTCGCCATCTTTCGCA
CGCTTGAGGTACTCACCCCATTCGTAGGTGACGATTTTGGCCTGCACGCCCACTTTCGCCCAGTCTGCCT
GAATCATCTCCGCCATGCGGCGAGCGTTCGGGTTATACGGACGTTGTACCGGCATCGCCCACAGGTCGAT
GGAGAAACCTTTTTCCAGACCCGCTTCTTTCAGCAAGGCTTTCGCTTTTTCAGGATCGTAGGTGTAATCC
TGAACGTCGTCGTTATAGCCCCACATGGTTGGCGGGATCAGGTTTTTCGCTGATACACCCGCGCCCTGAT
AAACCGCTTTGATGATCGCGTCTTTGTTCACCGCGTAGGTCAGTGCCTGGCGAACTTTCACGTCATCCAG
CGGTTTTTTCTGCACGTTATACGAGAGGTAGCCGACGTTCAGCCCCGGCATTTCCATCAGGTTGATGGAT
TTATCCTGCTTCATGCGAGCGATATCTGCCGGGTTCGGGTACGGCATCACCTGGCATTCATTCTTCTGCA
ATTTCGCGTAACGCACGGAAGCATCAGGGGTAATAGAGAAGACCAGCGTATCGATCTGCGGTTTGGTGCC
CCAGTAGCCATCAAACGCTTTGTAGCGGATACGGGAATCTTTTTGGTACTGCTGTAACTGGAATGGACCG
GTTCCGATTGGGTTGAGGTCCAGTTTTTCCGGTGTACCGGCTTTCATCATCGCATCAGCATATTCTTTTG
ACAGAATAGAGGCGAAGTCCATTGCCAGATCAGCGAGGAACGGCGCTTCCGGGCGAGTCAGCACGAACTG
AACTGTGTTGTCGTCCACCTTTTTCACTTCGCTGATCAGCTCCGGCAAGCCCATGCCTTCGAAGTATTCG
TAGCTACCGCCAGAAACTTTATGGTACGGGTTTTGCGCGTTTTTCTGACGATCGAACGAGAACACCACGT
CATCGGCGTTCAGTTCGCGCGTCGGTTTGAATTCTTTATTGTCATGCCACTTCACACCTTTACGCAGATG
GAAGGTATAGGTTTTACCGTCTTCGCTGACTTCCCACTTTTCAGCGAGGCCCGGGATCACTTCAGTGGTG
CCGATTTTAAATTCAACCAGGCGGTTATAAAGCGGTACGGAAGAGGCGTCATAGGTGGTGCCGGAGGTAA
ACAGCTGCGGGTTAAACCCTTCCGGAGATCCTTCTGAGCAATAAACCAGAGTTTTAGCCTGAACACTTGC
TGCGACGGTCATAGCCACCAGGCTGAGACCAAGCTTCAGCATCCCTGACTTTTTCAAGGAAATACGCA
Protein Sequence 
>gi|157159059|ref|YP_001465018.1| dipeptide ABC transporter periplasmic dipeptide-binding protein [Escherichia coli E24377A] MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dppA mutant was attenuated 10- to 50-fold compared to the wild type for colonization of the bladders and kidneys of mice (Haugen et al., 2007).
COG COG0747E, under E: Amino acid transport and metabolism
References
Haugen et al., 2007: Haugen BJ, Pellett S, Redford P, Hamilton HL, Roesch PL, Welch RA. In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infection and immunity. 2007; 75(1); 278-289. [PubMed: 17074858].