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PF13_0197

Victor ID 2018
Gene Name PF13_0197
Sequence Strain (Species/Organism) Plasmodium falciparum
NCBI Gene ID 814166
NCBI Protein GI 124513450
Locus Tag PF13_0197
Protein Accession XP_001350081.1
Other Database IDs UniProtKB-ID: Q8IDX8_PLAF7
UniRef100: UniRef100_Q8IDX8
UniRef90: UniRef90_Q8IDX8
UniRef50: UniRef50_Q8IDX8
UniParc: UPI00000791E2
EMBL: AL844509
EMBL-CDS: CAD52490.1
RefSeq_NT: XM_001350045.1
MINT: MINT-1545550
EnsemblGenome: PF13_0197.
GenomeReviews: AL844509_GR
KEGG: pfa:PF13_0197
NMPDR: fig|36329.1.peg.4939
EuPathDB: PlasmoDB:PF13_0197
Taxonomy ID 36329
Chromosome No 13
Gene Starting Position 1405256
Gene Ending Position 1406311
Gene Strand (Orientation) -
Protein Name merozoite surface protein 7
DNA Sequence 
>gi|23618947:1405256-1406311 Plasmodium falciparum 3D7 chromosome 13, complete genome, whole genome shotgun sequence
TTTACATTGTGTTTAGTAAATTAAATGAATATTCTAAGAATTTTTTATATTCCTCTTCTGGTTTTATTTT
TTTCTCACTTAAGTGACTATTTTGTTTTGCATAACTATAAACACCATAAATATAATTTTTAAATTGTTCA
TGGTATTCCTTATCTTTAAATAGTTTTATGAAAATTTCAGTCATATGTTTAGCTTCACTTACAATATCCG
TTTTGCCATTTTTACTCTTATTATCTTCTTGACCAAACATAATTATTAGATTTTTGATTATATCATATTC
TTTAGAATTTAAAACGAAGTCTTCATATTCTTTTTTGAAATCTGTATATTTTTTACCATATTCATCGAGA
TTTATTTTGTTCTTTTTGTTTGAAATATCAACTACATGATTAAAAACATCTCCTAAATTATATAATTTCT
TATCTAGGTCTTTTTGAAATGTCGATTCTCCTCCTTGTGCTGGTTTTTGTACTTCTTGTCCTTGTGTTGA
TATCTCTTGTTCATTTTTAGATTGAGTATCTGTTTCACTTTGTGCCTTTACCTTTGATAATACGTTTTTA
CCGAATAATCCTAAATTTTGGAATAATGGAAATGATTCTGATTTTTCCTTGTTTTCATCTTCTTGTTCAT
TTTCTACTGCGTCATCATCAACATTTTCAAAATGTGAATCGTTATTTTGTCCTAAGAATGTGTCATCATT
CATATCTAATTCATATGTATTGTCATCATCATTATTTTCTTCGTTATCATCATTTTCTTCATTTTTTTCT
ATTTCATCAATAATTGAATTTCCATTAATTAATACATGTACATTTTTTTCTTTACTGTTTTGTAATTCTT
CAATTTTTTTGTTTAATAATTCTTCATTATTTTTATAATTTCCAACAAAATCTCCTGATACTATATTTTT
TAGTTTTTCCAATTTTTTATTTTTAATATATAATTCTTCTTGATCTTCTTCATTATTTACTGGTGTACTA
TGAGTTGATTGATTACACGAAACATAGTATAAGTACACAAAAAAAAAAGAAAAATAAAATATGATATTAC
TCTTCA
Protein Sequence 
>gi|124513450|ref|XP_001350081.1| Merozoite Surface Protein 7 precursor, MSP7 [Plasmodium falciparum 3D7] MKSNIIFYFSFFFVYLYYVSCNQSTHSTPVNNEEDQEELYIKNKKLEKLKNIVSGDFVGNYKNNEELLNKKIEELQNSKEKNVHVLINGNSIIDEIEKNEENDDNEENNDDDNTYELDMNDDTFLGQNNDSHFENVDDDAVENEQEDENKEKSESFPLFQNLGLFGKNVLSKVKAQSETDTQSKNEQEISTQGQEVQKPAQGGESTFQKDLDKKLYNLGDVFNHVVDISNKKNKINLDEYGKKYTDFKKEYEDFVLNSKEYDIIKNLIIMFGQEDNKSKNGKTDIVSEAKHMTEIFIKLFKDKEYHEQFKNYIYGVYSYAKQNSHLSEKKIKPEEEYKKFLEYSFNLLNTM
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: msp7 mutant is attenuated for invasion of erythrocytes compared to the wild type (Kadekoppala et al., 2008).
References
Kadekoppala et al., 2008: Kadekoppala M, O'Donnell RA, Grainger M, Crabb BS, Holder AA. Deletion of the Plasmodium falciparum merozoite surface protein 7 gene impairs parasite invasion of erythrocytes. Eukaryotic cell. 2008; 7(12); 2123-2132. [PubMed: 18820076].