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PFD0215c

Victor ID 1978
Gene Name PFD0215c
Sequence Strain (Species/Organism) Plasmodium falciparum
NCBI Gene ID 812450
NCBI Protein GI 124505229
Locus Tag PFD0215c
Protein Accession XP_001351356.1
Other Database IDs UniProtKB-ID: Q8I1Y5_PLAF7
UniRef100: UniRef100_Q8I1Y5
UniRef90: UniRef90_Q8I1Y5
UniRef50: UniRef50_Q8I1Y5
UniParc: UPI0001981F6F
EMBL: AL844503
EMBL-CDS: CAD49136.2
RefSeq_NT: XM_001351320.2
MINT: MINT-1602877
EnsemblGenome: PFD0210c.
KEGG: pfa:PFD0210c
EuPathDB: PlasmoDB:PFD0215c
HOGENOM: HBG627630
ProtClustDB: CLSZ2433359
Taxonomy ID 36329
Chromosome No 4
Gene Starting Position 244819
Gene Ending Position 248806
Gene Strand (Orientation) -
Protein Name pbs36 homologue
DNA Sequence 
>gi|23509994:244819-248806 Plasmodium falciparum 3D7 chromosome 4
TCTAACTTTCTACAGTTTTATTTATGTTAAATAAACCTATACCCTTCCCTTGTGGGAAATTACAATGACA
ATAAAATAAAATATCATGAGGTACATTCTCAGGAATCCATAAATACGAAATAGTACTATATTTTTGAAAT
TTTTTATCTTTTGGAAAAGAATAAACTTCAGGATAATACTTTGCTTCAGGCAGTAAATTATTTACATTCA
TTGTTACAACACGTAAAAAAGACATAGAAATAGATACATTAGAAAAACAGTGTGGAGGCCTCAATTGTAT
TACATCGAAATTATTCTTATTATTTTTATTTTGATGCTTCTTCTTCTTATTATTAATAGTAGTAGTAGTA
GTATATTCTTCAAAATTTATACAATTCATACCTACGACTTCTCCTGGATTTGCATTTATTTCACAAAGAA
AATTTTCTTCTTGTTTTAATGTGTTTGTTAAAAATTGATGTTTCCCTTTATTATTTCCATAATCACAACC
TTTAATAAATTCTCCTTCCTTATTAAAACTATTATTAGCTTTTACATGTATCTTAAGATAGGGTGTGATA
GCTTCACTGTCTTTGCTACTTTCACATGTACATACTATTGTTATATCTTCCTTTACATAGAATGGCATGT
AAATTCCCACATTATATCTATCAAACATATTTAAATTTTCTATTATAATACCAGGAAGGGTATCCATTAT
AGGTTCTTCTTGATTATTTATAACTAAACGATCTCGTATTCCTATAAATTTAAAACAATAACGATCATCA
TACTCTTCATAACTTTTATTAATTGGACATAATAATTTTATCATCTTATTATAGTCATAATTAACTGTGC
ATGTTTCATTAGCATAATCCTTCAAATTACATATGTAATAATTTCCCACTTGTAATTCTTTTACATATAA
TCCCGACACACCACAAAAAAAAACAAAAAAAGGATGCCATCCCACATTCGAGTGTAAACAAATGATTAAA
AAAAAATATATCACCTTTCTCATCTTAACGAAAAAAAATGAAAAAAAAACAAAAATACAAAAAGAGTACG
AAAGGGCAATAAATAAAAATAAATTTGTCACAACTGGATACACATTATGAAAATTGGCCATTATATATTC
CTCCCAAATATTATAAGCCATATTAAAATATGTCAGTTCTTAAAAAGTTGATGAGTAGCAAAGTTAACGT
ATTTTTCAAGCATTCATCATAAAAAAAAATAAAATATATATATATATATATATATGTGTACATATATTAA
GATATATATATATATATATATATATTTTTTTTTTTGAACATTTGAAGAGTCTCTATTCCAATTATTGTTT
CTTATTGGTACATATCAAACTCACATTTATCATTTTGGTATATCTTTTTCTAATAATACATTGCAACAGT
TCCTTTTTTCTTGTCATATGAAAAAGCAACATTTTGCTATACTCTCCTAAATAATAAGATAAAATGATTT
TTTATTTTATTTAAAATTTTATTTTTTTTAATTTATTTTATATCAGCATGCAGTGGCATGTAGAACTCAC
ACTAAGTGTGTAACAAGCCCCAATTTTTTTCTTTTTTTTTCTTTCTTTTTTTTTTAAAAAAAGGGTACAT
ATATATATTTTTCTCTTTTTAATATATAAAAATTTTTATCGTTAAATTATAAAATTTATAAGTTTTCTTT
CTTCTCTTTCCATTTTCCTTTTTTTTTTTTTTTATGAACATGTTCATGCATTTACGAAAAAATAAAATAT
TACATGTACATGTTCATAAAAAAAAAAAAAAAAATAGCTACACATGTAAAATAAAAAAAAAAAATAATAC
ACCCTTTATTTTAATATATTCCTTTTTGTATCATATATCATTTTATTTATTATTTTATTTTTTTTTTTTT
TAGTATGTATATTATTCATATATTAATTTATATAGAATAAAATTAAATTATAACCACTATTTATTTCCAT
ATACTTTAAAGAAAAAATATAAATTTCCAAAATATATGTTAAGCAAAATTATTATACATGTTAAATAATT
GTAAGAAATAATATTTTTCTAAATTCTGACTAAATGTGTAAAACAACTATTACTGAAATTATCACAAATA
TACAGAACAAATCTAAAATATCCATGAATAAATAAATAAATCAATATATATATATATATATATATATTTC
TTTTTTTTAAGTATAAAGAAAAATTACTAAAGATTTTATAGTTTTAATTATATTAAAATACAACAAAAAA
AAAAAAAAAAATAAAGAAAAAAAAATGAATGATTAAAAAATAAAAACAAAAAAATTCATCATATTATATA
TAAATATATTTTTTTTATTTATACATATGTGTATATATATCATTTGGGATACACTGACAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAATGTTCATTTTTATAAAACCATATTTCATTTATATATATATATTT
TATATATATATTTATATATACATCATAATATTAAAATATGGATAAATATAAAACAAAAAAAAAAAAATAA
ATATATTAAATATATATTAATATATTAAGTTATTATGTTGAATATATATATATTAAAAATATGAATAATA
TTAAGAAATTATTAAATAATATATATTTAGAAGAAGATAATCCAAAAAGATTTTGCCAGAATGTTCTTGT
TCGTATTCTTGTTCTATCAGAATGTAAATCATATTTATTATTATAATGATATGTATCATATTGATCGTGA
ATATTTGTATTAGTTTTATAACTATTTTTAGAATTTTTTTCATGGTCATAATTTTTATAATGTTCATTTA
TATATTTGGAAATATCATCATAATTATAATTTACATTATTAATTTTATTTTCATAATTATTATATTGATT
GTTATTATGATGTTCCTCATTATTTATATAATTATCATCTGTATTCATTTTTTTATCATATTCATTTCCT
TCATCCTTTTTATATTCTTTTTTTTTCATATATTTATTTTGAAAAATCTGTTCTTCATCATTATTATTAT
TATTATTATCAAACATTAAGCTGTTAATATTTTTTGTGTAAATGATCATGGTACCAACGAATTCATCTCG
TTTACATGTACAGCTAATTTTAATATTTTCAGTTAAATTATTCGGTAATATTAAATAGGAAGAAAAAGAA
TGATTTCTAGATAATTTGACATCTGATGAAGGGTCAGGGATAACTCTAGAATTAGGTATTACATTTTTAG
AATTTAATATAAGATCAGCTCCAAAATAAACATCATGAAAACAATTACTAGGATTTAATTCTAAATTATT
ATTATAAGAATTATTAATTTCTTTTTTAAAACAATTTATGCCCAATACATCATTTGAATAAGCATGAATA
ATACAACTAGATCGTTCATTCAAACTTAAACTATTAGTTAGATCCCTTTTGGAAGGTATATTATCACCAA
AATCACAACCCTTAATTTTTTTCCTTGTTTTTTTTATATTTATTCTCATTATATGTTTTACTTTGTCTTG
TTTATCTCCGTAACACAAGCAACTAAAATCAATATCCATATTTGAATAAGGAGTACTATATAAACTATAT
GTGTCATTTAATCTGTTTTCGTTCGTACCAAATAAATTCGGATAAATACTATAAGTATCAACCTCGGGGG
AATTTTCGGTTGGATTACTTTGATTAACAAAGGCTCTAGAAGGGCAATTTTCTGGGTGAGTTTTTGCCGT
AGTACTAAAAGCATCATTCATATTACACACAAATAATAACAACTTCCCAAATTCATTATTCAATATGCAT
TCTTGAGCTTCATCTGAATTTACATTCACTACACAGATGTCTACATTACCAATGCTTATAACATCTTGAA
TCACATTGCTACACACAAAATTGATATTAATATTAAAATTAAAATTAATAATAAATGACAAAAAAATAAA
ATATACAAACAACTTTTTTCTCTTCATTGTAAAATGGTAACACATATGAATAAGCACCAATACATACA
Protein Sequence 
>gi|296004390|ref|XP_001351356.2| pbs36 homologue [Plasmodium falciparum 3D7] MAYNIWEEYIMANFHNVYPVVTNLFLFIALSYSFCIFVFFSFFFVKMRKVIYFFLIICLHSNVGWHPFFVFFCGVSGLYVKELQVGNYYICNLKDYANETCTVNYDYNKMIKLLCPINKSYEEYDDRYCFKFIGIRDRLVINNQEEPIMDTLPGIIIENLNMFDRYNVGIYMPFYVKEDITIVCTCESSKDSEAITPYLKIHVKANNSFNKEGEFIKGCDYGNNKGKHQFLTNTLKQEENFLCEINANPGEVVGMNCINFEEYTTTTTINNKKKKHQNKNNKNNFDVIQLRPPHCFSNVSISMSFLRVVTMNVNNLLPEAKYYPEVYSFPKDKKFQKYSTISYLWIPENVPHDILFYCHCNFPQGKGIGLFNINKTVES
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pbs36 had arrested intracellular growth in liver HC-04 cells (VanBuskirk et al., 2009).
References
VanBuskirk et al., 2009: VanBuskirk KM, O'Neill MT, De La Vega P, Maier AG, Krzych U, Williams J, Dowler MG, Sacci JB Jr, Kangwanrangsan N, Tsuboi T, Kneteman NM, Heppner DG Jr, Murdock BA, Mikolajczak SA, Aly AS, Cowman AF, Kappe SH. Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design. Proceedings of the National Academy of Sciences of the United States of America. 2009; 106(31); 13004-13009. [PubMed: 19625622].