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yfeA from Yersinia pestis Angola

Victor ID 1952
Gene Name yfeA from Yersinia pestis Angola
Sequence Strain (Species/Organism) Yersinia pestis Angola
NCBI Gene ID 5801102
NCBI Protein GI 162419227
Locus Tag YpAngola_A2630
Protein Accession YP_001607037.1
Other Database IDs UniProtKB-ID: A9R0B3_YERPG
UniRef100: UniRef100_Q56952
UniRef90: UniRef90_Q56952
UniRef50: UniRef50_Q56952
UniParc: UPI0000170607
EMBL: CP000901
EMBL-CDS: ABX85990.1
RefSeq_NT: NC_010159.1
GenomeReviews: CP000901_GR
KEGG: ypg:YpAngola_A2630
HOGENOM: HBG731008
OMA: VVTEGIT
ProtClustDB: CLSK889181
BioCyc: YPES349746:YPANGOLA_A2630-MONOMER
Taxonomy ID 349746
Gene Starting Position 2753284
Gene Ending Position 2754252
Gene Strand (Orientation) +
Protein Name chelated iron ABC transporter, periplasmic iron binding protein YfeA
DNA Sequence 
>gi|162418099:2753284-2754252 Yersinia pestis Angola, complete genome
GATGTTAATTAAGAAAAAAAGTCCTTATCTCAAAATGATAGAACGACTAAACTCCCCTTTTCTACGGGCT
GCAGCCTTGTTTACAATTGTCGCATTCTCATCGCTGATCAGTACCGCTGCTTTAGCAGAAAATAATCCCA
GCGATACAGCCAAAAAATTCAAAGTTGTGACTACATTCACAATCATTCAGGATATTGCACAAAATATCGC
CGGTGATGTTGCCGTGGTGGAGTCAATAACCAAGCCAGGCGCAGAGATTCATGACTATCAACCTACCCCA
CGAGATATTGTAAAAGCACAGTCAGCAGACCTTATCTTATGGAATGGCATGAATCTGGAGCGTTGGTTTG
AGAAGTTCTTCGAAAGTATTAAAGATGTCCCGTCTGCCGTCGTGACCGCAGGTATTACACCCCTGCCTAT
CCGTGAAGGCCCCTATAGCGGCATTGCCAACCCACATGCCTGGATGTCGCCATCAAATGCGCTAATATAT
ATTGAGAATATCCGCAAAGCGTTAGTTGAACACGATCCCGCTCATGCAGAAACCTATAACCGTAACGCGC
AAGCCTATGCTGAAAAAATTAAGGCGCTAGATGCTCCACTGCGTGAGCGTTTATCTCGTATTCCTGCGGA
ACAGCGTTGGTTAGTAACCAGTGAAGGGGCATTTAGTTATCTTGCCAAAGACTATGGTTTTAAAGAGGTT
TACTTATGGCCAATCAATGCAGAGCAACAAGGTATTCCGCAACAAGTTAGACACGTGATTGATATTATTC
GCGAAAATAAAATTCCGGTGGTGTTTAGTGAGAGTACTATTTCCGACAAACCCGCCAAACAAGTGAGTAA
AGAAACCGGTGCACAATATGGCGGCGTGCTATATGTTGATTCTCTGTCGGGCGAAAAAGGCCCGGTCCCC
ACTTACATCAGTTTAATTAACATGACTGTAGATACTATCGCTAAAGGATTCGGTCAATG
Protein Sequence 
>gi|162419227|ref|YP_001607037.1| periplasmic-binding protein [Yersinia pestis Angola] MLIKKKSPYLKMIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESITKPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNALIYIENIRKALVEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINAEQQGIPQQVRHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKGFGQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yfeAB mutant is attenuated when given subcutaneously to mice and is avirulent when given to mice intravenously (Bearden and Perry, 1999).
COG COG0803P, under P: Inorganic ion transport and metabolism
References
Bearden and Perry, 1999: Bearden SW, Perry RD. The Yfe system of Yersinia pestis transports iron and manganese and is required for full virulence of plague. Molecular microbiology. 1999; 32(2); 403-414. [PubMed: 10231495].