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purK from Yersinia pestis Angola

Victor ID 1944
Gene Name purK from Yersinia pestis Angola
Sequence Strain (Species/Organism) Yersinia pestis Angola
NCBI Gene ID 5799740
NCBI Protein GI 162419683
Locus Tag YpAngola_A1274
Protein Accession YP_001605809.1
Other Database IDs UniProtKB-ID: A9R249_YERPG
UniRef100: UniRef100_A4TP67
UniRef90: UniRef90_A4TP67
UniRef50: UniRef50_P43850
UniParc: UPI00000DC82F
EMBL: CP000901
EMBL-CDS: ABX86446.1
RefSeq_NT: NC_010159.1
GenomeReviews: CP000901_GR
KEGG: ypg:YpAngola_A1274
HOGENOM: HBG516369
OMA: LADRSEW
ProtClustDB: PRK06019
BioCyc: YPES349746:YPANGOLA_A1274-MONOMER
Taxonomy ID 349746
Gene Starting Position 1333761
Gene Ending Position 1334825
Gene Strand (Orientation) -
Protein Name phosphoribosylaminoimidazole carboxylase, ATPase subunit
DNA Sequence 
>gi|162418099:1333761-1334825 Yersinia pestis Angola, complete genome
GTTATAACTTATCTTGCGCCCAACGCAGTGCGTTCTGATACTCCGCGGGTAGCAAAGGAGCCAGTGCGGC
CAGGGATGCGCTTAATGCCGTACCCTCTGGATCGTTTAAATTCAGATGACCAACTTTGCGGCCTTCACGG
ACTTCTTTGTCGTACCAATGCAGATGTACTAATGGCAGAGACAGCCACTGAATATTTACTGGCGTGCCAA
TCAGATTAACCATCGCTGACGGGGTATTCACCACCGGCTGCGGCAGTGGCAGATCCAAAATGGCCCGCAG
ATGCAATTCGAACTGGCTAATTGATGCGCCGTTTTGTGTCCAGTGACCACTGTTATGAACGCGCGGGGCC
AGTTCATTGATCAACAGACGGTCGCCGACGATAAAACACTCCATCGCCATCACACCGACATAATTCAGCT
TATCCATAATGGCTGACAGCATTTTTTCGGCTTGCTGCTGTAGTTTGCTGTTGGGCTGTGGTAATGCCAC
GCTCATGCGCAAAATGCCATCTTCATGCAGATTATGGGTCAGTGGATAAAATACCGATTCACCTTGGTGG
CTGCGCGCGCCGATCAATGAGACTTCGCCGGAGAAGTTAATCCCCTGTTCGACAATACACTCGCCGTAAG
CATCGGGGGGTAAGGTACCCTGCTCACCAGGGCGTAAACGCCATTGACCCCGGCCGTCATAGCCGCCGAC
CCGCCGTTTTACGATGGCTAGCTCACCCAACGTGGCGAACACCTCAGGCCATTCACTGGCGCTGGATAAC
AATTGCCACGGCGCAGTTGCCAAACCCAAGCTATCGAGTAACTGCTTTTGGGGCAGACGATCTGCCAGAC
GTGGAAAAATATCGCGATTAACAAAAGCAGTATGGGTAGCTAATTCACGGGTTAAGGCGGTTTCCGGCCA
ACGTTCAATTTCAGCGGTGATCACACTGTGCTGATAAGGCACCGCTTCAGGTTCAGCATCTAAGCCGACG
GGATAAACCGCAATTCCCAGCGGTTCACCTGCCTGCCGCAGCATTCGCCCTAACTGGCCATTACCCAGTA
CACAAACTGGTTTCA
Protein Sequence 
>gi|162419683|ref|YP_001605809.1| phosphoribosylaminoimidazole carboxylase ATPase subunit [Yersinia pestis Angola] MKPVCVLGNGQLGRMLRQAGEPLGIAVYPVGLDAEPEAVPYQHSVITAEIERWPETALTRELATHTAFVNRDIFPRLADRLPQKQLLDSLGLATAPWQLLSSASEWPEVFATLGELAIVKRRVGGYDGRGQWRLRPGEQGTLPPDAYGECIVEQGINFSGEVSLIGARSHQGESVFYPLTHNLHEDGILRMSVALPQPNSKLQQQAEKMLSAIMDKLNYVGVMAMECFIVGDRLLINELAPRVHNSGHWTQNGASISQFELHLRAILDLPLPQPVVNTPSAMVNLIGTPVNIQWLSLPLVHLHWYDKEVREGRKVGHLNLNDPEGTALSASLAALAPLLPAEYQNALRWAQDKL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purK mutant is attenuated in mice (Flashner et al., 2004).
COG COG0026F, under F: Nucleotide transport and metabolism
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].