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purH from Yersinia pestis Angola

Victor ID 1941
Gene Name purH from Yersinia pestis Angola
Sequence Strain (Species/Organism) Yersinia pestis Angola
NCBI Gene ID 5798929
NCBI Protein GI 162419129
Locus Tag YpAngola_A0465
Protein Accession YP_001605070.1
Other Database IDs UniProtKB-ID: PUR9_YERPG
UniRef100: UniRef100_A7FNG6
UniRef90: UniRef90_A1JIJ7
UniRef50: UniRef50_A9IZD0
UniParc: UPI00000CDA75
EMBL: CP000901
EMBL-CDS: ABX85892.1
RefSeq_NT: NC_010159.1
GenomeReviews: CP000901_GR
KEGG: ypg:YpAngola_A0465
HOGENOM: HBG498048
OMA: ASDGFFP
ProtClustDB: PRK00881
BioCyc: YPES349746:YPANGOLA_A0465-MONOMER
Taxonomy ID 349746
Gene Starting Position 485853
Gene Ending Position 487442
Gene Strand (Orientation) -
Protein Name bifunctional purine biosynthesis protein PurH
DNA Sequence 
>gi|162418099:485853-487442 Yersinia pestis Angola, complete genome
ATTAATGACGGAAATGGCGCATGTCGGTGAAGATCATGGCAATACTGTGTTCATCAGCAGCCGCGATGAC
TTCATCATCACGAATTGAGCCGCCCGGTTGGATGACACAAGTAATGCCCACAGCCGCGGCGGCATCAATA
CCATCACGGAACGGGAAGAAGGCATCAGAGGCCATGGCTGAGCCAGCCACTTCCAGCCCTTCATCTGCGG
CCTTGATACCGGCTATTTTCGCAGAGTACACGCGGCTCATTTGGCCGGCACCTATACCGATTGTCATGTT
ATCGCGGGCATAGACAATCGCATTGGATTTAACAAACTTAGCCACTTTCCAGCAGAACAGCGCATCACGC
AGTTCCTGTTCGGTAGGCTGACGCTTGGAAACCACGCGAAGGTCGGCCGCCGTCACCATACCTAAATCGC
GTTCTTGTACCAGCAAACCCCCATTAACACGTTTGAAATCTAAACCTGCTGAACGTGCTTGCCACTGGCC
ACAAGTCAGGACTCGGACATTTTGTTTAGCTGCAAGCAATGCCAATGCATCAGAGCTGACTGTTGGCGCA
ATGATCACTTCGACAAACTGGCGGCTGATGATCGCGCTGGCCGTTGCTGCATCCAATTCACGGTTAAAGG
CGATGATGCCACCGAAAGCTGAGGTTGGATCGGTTTGATAGGCACGTTCATAAGCGGCAAGAATAGAATC
ACCGATAGCCACACCGCATGGGTTGGCATGTTTAACGATCACACAGGCTGGTTCACTGAACTCTTTCACG
CATTCCAGCGCGGCATCGGTATCCGCAATATTGTTATAAGAGAGGGCTTTCCCTTGTAATTGCTGGGCAG
TGGCAACGGATGCCTCTTTGACATCTTCTTCTATATAGAAGGCAGCTTGCTGGTGGCTGTTTTCACCGTA
ACGCATATCCTGCTTCTTTATATAGTTAAGATTTAGGGTGCGAGGGAAGTGGCCGGAAGGCTGTTCCGTA
TCACCATGATAAGGTGGCACCAGTGTGCCGAAGTAGTTGGCGATCATGCTGTCGTAGGCGGCGGTGTGTT
CGAAAGCTTTAATGGCCAGATTGAAGCGGGTGGGGTAAGTCAACGAACCATCATTATTATCAAGCTCAGT
AATAATGGCGGGGTAGTCGCTACTCTTCACCACGATGGCGACATCTTTATGGTTCTTGGCCGCAGAGCGA
ACCATGGTTGGGCCACCAATATCAATATTCTCAACCGCATCTTCCAACGAGCAATCCGGGCGGGCAACCG
TCTGGGCGAAGGGATATAAATTAACGACGACAATATCAATGGGCTGAATGCCATGTTGAGCCATGATGCC
ATCATCCTGACCACGACGACCTAAAATCCCACCATGCACCTTTGGATGCAAAGTCTTCACACGTCCATCC
ATCATTTCCGGGAAACCGGTGTAGTCAGACACTTCGGTAACGGGTAAACCAGCATCAGCCAGCAGGCGGG
CAGTCCCACCGGTGGAAAGTAACTCGATACCGCGTTGAGAAAGTGCTTGGGCGAATTCGATGATACCTGC
TTTGTCAGACACACTGAGTAGAGCACGGCGGATTGGACGGCGTTGTTGCA
Protein Sequence 
>gi|162419129|ref|YP_001605070.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Yersinia pestis Angola] MQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSILAAYERAYQTDPTSAFGGIIAFNRELDAATASAIISRQFVEVIIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAADLRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHSIAMIFTDMRHFRH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purH mutant is attenuated in mice (Flashner et al., 2004).
COG COG0138F, under F: Nucleotide transport and metabolism
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].