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spoT from Yersinia pestis Angola

Victor ID 1939
Gene Name spoT from Yersinia pestis Angola
Sequence Strain (Species/Organism) Yersinia pestis Angola
NCBI Gene ID 5798508
NCBI Protein GI 162419160
Locus Tag YpAngola_A0043
Protein Accession YP_001604684.1
Other Database IDs UniProtKB-ID: A9R663_YERPG
UniRef100: UniRef100_A4TSE8
UniRef90: UniRef90_P0AG25
UniRef50: UniRef50_P0AG25
UniParc: UPI00000DCD6C
EMBL: CP000901
EMBL-CDS: ABX85923.1
RefSeq_NT: NC_010159.1
GenomeReviews: CP000901_GR
KEGG: ypg:YpAngola_A0043
HOGENOM: HBG594146
OMA: ARTAIRH
ProtClustDB: PRK11092
BioCyc: YPES349746:YPANGOLA_A0043-MONOMER
Taxonomy ID 349746
Gene Starting Position 50038
Gene Ending Position 52146
Gene Strand (Orientation) -
Protein Name guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
DNA Sequence 
>gi|162418099:50038-52146 Yersinia pestis Angola, complete genome
GTTAATTGCGATTACGGCTAACTTTAACCACATCTGGCATGATACGGATTTTACGCATAATGTTAGCCAG
ATGGACCCGGTTCCGAGTGGTCAGGCGAATAAAGGCGCTGTATACCCGGCCATCTTTTTCTTCTGTATTC
AAACTCTGAATATTGGATTCGGCGGCGTTAATCGCGGCGGTCAGATTGGCAAGCGCACCTTGTTGGTTAA
ACATATCGACTTTAATTTCGGCAATAAACTCTTGTTCAGTCTCTTGGTCCCATTCTACAGCCATAAATTT
CTCAGGCTCTTTCTGGTAACCACGGATATTCCGACAAGATTCGTGATGAATAACCAACCCTTTACCTGGG
CTGATATGGGCGATAATAGGGTCACCAGGGATTGGACGGCAGCACTTGGCAAACGTGATAAGTACGCCAT
CGGCACCTTTGATCGGTAACTTGCGGGTACCAGAAGCAGAGGTGCCCAGTGTTGATGGATCGCCCAATAG
GTTTTTAGCCACCACTACGCTCATGGCATTACCTAAACCAATTTCTGCCAGCAAGTCATCTACCGTAGCC
AGTTTCATTCTATCCAACTCGTGTTTGATATTTTCTTCAGAAATATCAGAGAGTTTACGCCCATTTCCTA
ATGCATGATTCAGTAACCGGCGACCAAGGCTGACCGATTCATCACGTTTAAGATTTTTCAGTAATTGACG
TATTTTGGCTCGCGCTTTTGAACTGACGACAAAATTCAGCCAGGCAGCATTTGGTCTGGCTCCTGGAGCG
GTAATAATCTCAACCGTCTGGCCACTACTCAGTGGCTGAGAGAGCGGGTACGGCTGACGATCAACGCGGG
CACCTACGCAGGCATGGCCGATATCGGTATGCACAACATAGGCAAAATCGACCGGTGTGGCACCAGCCGG
TAATTCCACAATGCGCCCTTCCGGGGTGAAAACGTAGATCTCATCAGGGAATAAATCAGATTTCACGCTT
TCAATAAATTCAAATGAGCTACCCGCGCTTTGTTGTAACTCCAGCAAGCTTTGCATCCACCGCTGAGCAC
GGATTTGAGCCGTGGTACCGGACTCACCTTGTTCTTTATAAGCCCAGTGTGCAGCAACCCCCATTTCGGC
CATCTGGTCCATATCTTCAGTACGGATTTGTACTTCTACCGGTACGCCATGGGGACCGATTAATGACGTA
TGTAATGATTGGTAGCCGTTAGCTTTAGGGATAGCGATATAGTCTTTTACGCGCCCAGGGCGGGGTTTAT
ACAGGCTATGAGCCTGCCCCAACACGCGGTAGCAAGTATCGACTTCTTTGACGATAACCCGAAAAGCATA
GATATCCATGATGGAATGGAAGCGCTGTTCTTTCAGGTGCATCTTGCAGTAGATGGAATACAGATGCTTC
TCACGGCCACTGACCCGGCAAGGAATGCCAGCCTCGGTCAAGCGCCCTTCAATCTCCGCGAGGATCTTCT
GAATCATCTCTTTGCGGTTACCGCGCGCGGCTTTTACCACTTCTTTAATGACGCGGTAACGATTGGGATA
GAGTGCTTCAAAACCCAGCTCTTCCAGCTCGGTTTTTAAATGATGAATACCCAGCCGGTGGGCTAGTGGG
CTGTATATCTCAAGGGTTTCGCGAGCAATGCGCCGACGTTTATCCGGGCGCAAAGAGCCCAGTGTGCGCA
TATTGTGTGTACGGTCAGCCAGTTTGATCAAAATGACGCGGATGTCTTGCACCATTGCCATGATCATTTT
GCGGAAGTTTTCCGCCTGGGCTTCTTTCTTGTCACGGAAGTTCAGTTTATCGAGTTTAGATACACCCTCG
ACTAACTCGGCTACGCTTTTCCCAAACAGCTGTTCCATATCTTGATATGTAGCAGGTGTATCTTCAATGA
CGTCATGTAATAGCGCCGCCATTAAGGTTTCGTAGTCGAGCCGCATCTCCGCGAGAATACAGGCCACAGC
AACCGGGTGAGTGATATAAGGCTCACCGCTGGAGCGTGTCTGCCCCTCGTGAGCATCACGTGCGACAAGA
TATGCCTGTTTGAGGCGCTTAATCTGCTCCTCTGGCAGGTAACGTTGAATCAGCAGATTCAGGCTTTCAA
ACAGGTACA
Protein Sequence 
>gi|162419160|ref|YP_001604684.1| bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [Yersinia pestis Angola] MYLFESLNLLIQRYLPEEQIKRLKQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMRLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSKLDKLNFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIARETLEIYSPLAHRLGIHHLKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILAEIEGRLTEAGIPCRVSGREKHLYSIYCKMHLKEQRFHSIMDIYAFRVIVKEVDTCYRVLGQAHSLYKPRPGRVKDYIAIPKANGYQSLHTSLIGPHGVPVEVQIRTEDMDQMAEMGVAAHWAYKEQGESGTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIVELPAGATPVDFAYVVHTDIGHACVGARVDRQPYPLSQPLSSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQLLKNLKRDESVSLGRRLLNHALGNGRKLSDISEENIKHELDRMKLATVDDLLAEIGLGNAMSVVVAKNLLGDPSTLGTSASGTRKLPIKGADGVLITFAKCCRPIPGDPIIAHISPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDQETEQEFIAEIKVDMFNQQGALANLTAAINAAESNIQSLNTEEKDGRVYSAFIRLTTRNRVHLANIMRKIRIMPDVVKVSRNRN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: relA spoT deletion mutants are attenuated in mice (Sun et al., 2009).
COG COG0317TK, under T: Signal transduction mechanisms; K: Transcription
References
Sun et al., 2009: Sun W, Roland KL, Branger CG, Kuang X, Curtiss R 3rd. The role of relA and spoT in Yersinia pestis KIM5 pathogenicity. PloS one. 2009; 4(8); e6720. [PubMed: 19701461].