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yopD from Yersinia pestis Angola

Victor ID 1935
Gene Name yopD from Yersinia pestis Angola
Sequence Strain (Species/Organism) Yersinia pestis Angola
NCBI Gene ID 5798303
NCBI Protein GI 162417734
Locus Tag YpAngola_B0029
Protein Accession YP_001604460.1
Other Database IDs UniProtKB-ID: A9R9H1_YERPG
UniRef100: UniRef100_Q06131
UniRef90: UniRef90_Q06131
UniRef50: UniRef50_Q06131
UniParc: UPI00000D606B
EMBL: CP000902
EMBL-CDS: ABX88701.1
RefSeq_NT: NC_010157.1
GenomeReviews: CP000902_GR
KEGG: ypg:YpAngola_B0029
HOGENOM: HBG299047
OMA: MAVVSGV
ProtClustDB: CLSK862121
BioCyc: YPES349746:YPANGOLA_B0029-MONOMER
Taxonomy ID 349746
Plasmid No new_pCD
Gene Starting Position 16933
Gene Ending Position 17853
Gene Strand (Orientation) -
Protein Name translocator protein YopD
DNA Sequence 
>gi|162417732:16933-17853 Yersinia pestis Angola plasmid new_pCD, complete sequence
GTCAGACAACACCAAAAGCGGCTTTCATGGCGTGAGTATGACTGCTAACATATTGTTCAATCAAGCGCAG
GACATCTTTCATAAAGTTATCATTATAGTTCATCGCCTCTTCGGCTTTTTGCTTCTCGTTGGCAGCAATA
CTTGCATTGACTTCTTTCTCTTTGACCTCGGCTTGAGAATACCCTTGATGAACTTGAATCGCACTGTTTG
CCATTTGTCCTAACGGCTGCGTTGCGGCATTAAACGCATTGGCTTTTGAGTCGGTCATTCTGAATTCTTT
ATCCAATAATGCCAGCTTATTTTGATCCGCTACCTGCTCTGGTTTCCATATTCTCCCGATATCCTCTCTG
CTTACCGCTTTATCACCAATGTTACTCATTTGCTGCATTTTTGTATCAATAAGTTGTTCGCGGCCAGCAA
TATTACTGTTTAGAATTTGTTCCTGTTTAACTATTTTCACCTCTTTCGCTATAGAAAAAGCACTAGCAAC
CGTAGAAGTAGCAGCCATGATGCCAGACACCACCGCCATGGCGATCATCAGTTTTGCACCGCTGACCATC
TCCGCTACCTGCTCCTTTTGGGCAGTAATAGTAGCTTTATTTTCTATATCCCTTTGTTGCAAACCCATTT
CTCGCGCTTTACGTGCCAGTTCCAACAGCAACAACAAGATACTTAAAGTACCATTAAGATCACCCTGGCT
TTTACTCAGTAATGCAACATTGATTCCCTGGCTCGGTTTGATCAATTCTGGCACCTGTGACCGAGATAAG
CTTGCCTCGCTACTCTTTATTGCTTGTGCTTCATGACGGGTGTCTTCTGTTTTTTTAATCTCACCGCTTT
GCTTGACTGTCTCTGTAGTGATGGCATCAAGCTGTGAACCGGTCGTGATAATTGGGCTGTCTGTCTTGAT
ATTTATTGTCA
Protein Sequence 
>gi|162417734|ref|YP_001604460.1| translocator protein YopD [Yersinia pestis Angola] MTINIKTDSPIITTGSQLDAITTETVKQSGEIKKTEDTRHEAQAIKSSEASLSRSQVPELIKPSQGINVALLSKSQGDLNGTLSILLLLLELARKAREMGLQQRDIENKATITAQKEQVAEMVSGAKLMIAMAVVSGIMAATSTVASAFSIAKEVKIVKQEQILNSNIAGREQLIDTKMQQMSNIGDKAVSREDIGRIWKPEQVADQNKLALLDKEFRMTDSKANAFNAATQPLGQMANSAIQVHQGYSQAEVKEKEVNASIAANEKQKAEEAMNYNDNFMKDVLRLIEQYVSSHTHAMKAAFGVV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopD mutants are unable to induce cytotoxicity in HeLa cells (Rosqvist et al., 1991).
References
Rosqvist et al., 1991: Rosqvist R, Forsberg A, Wolf-Watz H. Intracellular targeting of the Yersinia YopE cytotoxin in mammalian cells induces actin microfilament disruption. Infection and immunity. 1991; 59(12); 4562-4569. [PubMed: 1937815].