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yopM from Yersinia pestis Angola

Victor ID 1933
Gene Name yopM from Yersinia pestis Angola
Sequence Strain (Species/Organism) Yersinia pestis Angola
NCBI Gene ID 5798276
NCBI Protein GI 162417819
Locus Tag YpAngola_B0025
Protein Accession YP_001604457.1
Other Database IDs UniProtKB-ID: A9R9G8_YERPG
UniRef100: UniRef100_A9R9G8
UniRef90: UniRef90_A9R9G8
UniRef50: UniRef50_P17778
UniParc: UPI0001613DA2
EMBL: CP000902
EMBL-CDS: ABX88786.1
RefSeq_NT: NC_010157.1
GenomeReviews: CP000902_GR
KEGG: ypg:YpAngola_B0025
HOGENOM: HBG758074
OMA: VRENDLT
ProtClustDB: CLSK862120
BioCyc: YPES349746:YPANGOLA_B0025-MONOMER
Taxonomy ID 349746
Plasmid No new_pCD
Gene Starting Position 14101
Gene Ending Position 15267
Gene Strand (Orientation) -
Protein Name effector protein YopM
DNA Sequence 
>gi|162417732:14101-15267 Yersinia pestis Angola plasmid new_pCD, complete sequence
ACTACTCAAATACATCATCTTCAAGTTTGTCTGTAGTCTCATGAGCAAATTCATATGGATCAACTACACG
TTCAGAGTTCATCCGAAGATCTTCCACTGACTCAGGTATATCGGGAAACTCTCTCAGAGGGTTGTACTCT
ACGTGGAGCTGTTTCAGGTTTTGCGGCAATTCAGGTACTTCAGCAAGATGATTAAATGAAGCGATTAAAC
GTTCTAAGCGTGGAGGTAACGCTGGCAGTTCGATCAACTTATTATTACTGACATTAAGTTCTTCCAGTGA
AGGGGGTAAATCGCATAAGGATCTTATTTCATTGCTGGATGCATTGAGATAATACAAGTTTGGTGGCAAT
TCCGATAATCCAGAAAAAATATTTTCAGAAACATCTAAGAAGGTTAAACTCTGCGGTAATTCTGGCAGAT
CAGTTAAATAATTATCTCTGACATTAAGTGCTTCCAGGGAAGGGGGTAAATCGGGTAATGTTTTCAGTAA
ATTGTTATCAGCATAAATCGTAGTCAAGAAGGGCAAGTTTTGCAACTCTGGCAATTCTTCCAGAATATTA
TTACCAGCAACAATAGATTCCAGTGAAAGAGGTAAATCAGGTAGTTTTTTCAGTGAATTGTTATCAACAT
CAATAATTTTCAAGAAGGACGAGTTTTGCAACTCTGGCAATTTTTCCAGCTGATTATTAGAGACACCTAA
ATATTCCAGTAAAGGTGGTAAATCGGATAATGCCTTCAGATTGTTATTATCAACTAGAAGTGATTTCAGG
CTCTGCGGTAATTCCGGTAATTCTGTAAGAGAATTACATGACGCCACTAAACTCTCTAAATGCGGAGGTA
ATTCCGGCAAAGAACTCAGCCCCAGATTATTTAGTTCTAGCTCATGGGCTTGTCGGTCCAGGCAATCTCG
TAACCTTGAAACCGCCATTTCCCTCTGTTCACCATTCCCCGGAGGGGCATTTCGTTCCCATTCCGACCAT
GCATTATAATATTCAGTCTTAGATTTAACATTTTCTGCCTCAACCGGCATCTCAGTTAAATTAGAAGAAT
GACGTAATGGTTCTTGCAAAAAAGTATTAGATACATTTCTTGGATTTATGAACATATTGAATGCCTTTCT
GAAAATATTTTTATTATCGAGTTTTTCACTGCAAACAAAAACATACA
Protein Sequence 
>gi|162417819|ref|YP_001604457.1| effector protein YopM [Yersinia pestis Angola] MYVFVCSEKLDNKNIFRKAFNMFINPRNVSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPELPPHLESLVASCNSLTELPELPQSLKSLLVDNNNLKALSDLPPLLEYLGVSNNQLEKLPELQNSSFLKIIDVDNNSLKKLPDLPLSLESIVAGNNILEELPELQNLPFLTTIYADNNLLKTLPDLPPSLEALNVRDNYLTDLPELPQSLTFLDVSENIFSGLSELPPNLYYLNASSNEIRSLCDLPPSLEELNVSNNKLIELPALPPRLERLIASFNHLAEVPELPQNLKQLHVEYNPLREFPDIPESVEDLRMNSERVVDPYEFAHETTDKLEDDVFE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopM mutant is attenuated in mice compared to the wild type (Leung et al., 1990).
COG COG4886S, under S: Function unknown
References
Leung et al., 1990: Leung KY, Reisner BS, Straley SC. YopM inhibits platelet aggregation and is necessary for virulence of Yersinia pestis in mice. Infection and immunity. 1990; 58(10); 3262-3271. [PubMed: 2401564].