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yopE from Yersinia pestis Angola

Victor ID 1930
Gene Name yopE from Yersinia pestis Angola
Sequence Strain (Species/Organism) Yersinia pestis Angola
NCBI Gene ID 5798272
NCBI Protein GI 162417742
Locus Tag YpAngola_B0003
Protein Accession YP_001604439.1
Other Database IDs UniProtKB-ID: A9R9F0_YERPG
UniRef100: UniRef100_P31493
UniRef90: UniRef90_P31493
UniRef50: UniRef50_P31493
UniParc: UPI000013BCAD
EMBL: CP000902
EMBL-CDS: ABX88709.1
RefSeq_NT: NC_010157.1
GenomeReviews: CP000902_GR
KEGG: ypg:YpAngola_B0003
HOGENOM: HBG758070
OMA: KSEQYAN
ProtClustDB: CLSK862154
BioCyc: YPES349746:YPANGOLA_B0003-MONOMER
Taxonomy ID 349746
Plasmid No new_pCD
Gene Starting Position 1365
Gene Ending Position 2024
Gene Strand (Orientation) +
Protein Name outer membrane virulence protein YopE
DNA Sequence 
>gi|162417732:1365-2024 Yersinia pestis Angola plasmid new_pCD, complete sequence
CATGAAAATATCATCATTTATTTCTACATCACTGCCCCTGCCGACATCTGTGTCAGGATCTAGCAGCGTA
GGAGAAATGTCTGGGCGCTCAGTCTCACAGCAAACAAGTGATCAATATGCAAACAATCTGGCCGGGCGCA
CTGAAAGCCCTCAGGGTTCCAGCTTAGCCAGCCGTATCATTGAGAGGTTATCATCAGTGGCCCACTCTGT
GATTGGGTTTATCCAACGCATGTTCTCGGAGGGGAGCCATAAACCGGTGGTGACACCAGCACCCACACCT
GCACAAATGCCAAGTCCTACGTCTTTCAGTGACAGTATCAAGCAACTTGCTGCTGAGACGCTGCCAAAAT
ACATGCAGCAGTTGAATAGCTTGGATGCAGAGATGCTGCAGAAAAATCATGATCAGTTCGCTACGGGCAG
CGGCCCTCTTCGTGGCAGTATCACTCAATGCCAAGGGCTGATGCAGTTTTGTGGTGGGGAATTGCAAGCT
GAGGCCAGTGCCATCTTAAACACGCCTGTTTGTGGTATTCCCTTCTCGCAGTGGGGAACTATTGGTGGGG
CGGCCAGCGCGTACGTCGCCAGTGGCGTTGATCTAACGCAGGCAGCAAATGAGATCAAAGGGCTGGCGCA
ACAGATGCAGAAATTACTGTCATTGATGTG
Protein Sequence 
>gi|162417742|ref|YP_001604439.1| outer membrane virulence protein YopE [Yersinia pestis Angola] MKISSFISTSLPLPTSVSGSSSVGEMSGRSVSQQTSDQYANNLAGRTESPQGSSLASRIIERLSSVAHSVIGFIQRMFSEGSHKPVVTPAPTPAQMPSPTSFSDSIKQLAAETLPKYMQQLNSLDAEMLQKNHDQFATGSGPLRGSITQCQGLMQFCGGELQAEASAILNTPVCGIPFSQWGTIGGAASAYVASGVDLTQAANEIKGLAQQMQKLLSLM
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopE mutants are attenuated after oral or intraperitoneal infection in mice, but are not attenuated after intravenous infection in mice (Rosqvist et al., 1990).
References
Rosqvist et al., 1990: Rosqvist R, Forsberg A, Rimpiläinen M, Bergman T, Wolf-Watz H. The cytotoxic protein YopE of Yersinia obstructs the primary host defence. Molecular microbiology. 1990; 4(4); 657-667. [PubMed: 2191183].