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plc from Clostridium perfringens SM101

Victor ID 1925
Gene Name plc from Clostridium perfringens SM101
Sequence Strain (Species/Organism) Clostridium perfringens SM101
NCBI Gene ID 4205371
NCBI Protein GI 110802823
Locus Tag CPR_0041
Protein Accession YP_697384.1
Other Database IDs UniProtKB-ID: Q0SWV3_CLOPS
UniRef100: UniRef100_Q0SWV3
UniRef90: UniRef90_Q0TV31
UniRef50: UniRef50_Q0TV31
UniParc: UPI000016EB6B
EMBL: CP000312
EMBL-CDS: ABG86694.1
RefSeq_NT: NC_008262.1
GenomeReviews: CP000312_GR
KEGG: cpr:CPR_0041
TIGR: CPR_0041
eggNOG: NOG147197
HOGENOM: HBG061692
OMA: GSTYPDY
ProtClustDB: CLSK566902
BioCyc: CPER289380:CPR_0041-MONOMER
Taxonomy ID 289380
Gene Starting Position 48156
Gene Ending Position 49352
Gene Strand (Orientation) +
Protein Name phospholipase C
DNA Sequence 
>gi|110801439:48156-49352 Clostridium perfringens SM101 chromosome, complete genome
AATGAAAAGAAAGATTTGTAAGGCGCTTGTTTGTGCCACGCTAGTAACTAGCCTATGGGCTGGGGTATCA
ACTAAAGTCTACGCTTGGGATGGAAAAATTGATGGAACAGGAACTCATGCTATGATTGTAACTCAAGGTG
TTTCAATCTTAGAAAATGATATGTCCAAAAATGAACCAGAAAGTGTAAGAAAAAACTTAGAGATTTTAAA
AGATAACATGCATGAGCTTCAATTAGGTTCTACTTATCCAGATTATGATAAGAATGCATATGATCTATAT
CAAGATCATTTCTGGGATCCTGATACAAATAATAATTTCTCAAAGGATAATAGTTGGTATTTAGCTTATT
CTATACCTGACACAGGGGAATCACAAATAAGAAAATTTTCAGCATTAGCTAGATATGAATGGCAAAGAGG
AAATTATAAACAAGCTACATTCTATCTTGGAGAAGCTATGCACTATTTTGGAGATATAGATACTCCATAT
CATCCTGCTAATGTTACTGCCGTTGATAGCGCAGGACATGTTAAGTTTGAGACTTTTGCAGAAGAAAGGA
AAGAACAGTATAAAATAAACACAGTAGGTTGCAAAACTAATGAGGATTTTTATGCTGATATCTTAAAAAA
CAAAGATTTTAATGCATGGTCAAAAGAATATGCAAGAGGTTTTGCTAAAACAGGGAAATCAATATACTAT
AGTCATGCTAGCATGAGTCATAGTTGGGATGATTGGGATTATGCAGCAAAGGTAACTTTAGCTAACTCTC
AAAAAGGAACAGCAGGATATATTTATAGATTCTTACACGATGTATCAGAGGGTAATGATCCATCAGTTGG
AAATAATGTAAAAGAACTAGTAGCTTACATATCAACTAGTGGTGAAAAAGATGCTGGAACAGATGACTAC
ATGTATTTTGGAATCAAAACAAAGGATGGAAAAACTCAAGAATGGGAAATGGACAACCCAGGAAATGATT
TTATGGCTGGAAGCAAAGACACTTATACTTTCAAATTAAAAGATGAAAATCTAAAAATTGATGATATACA
AAATATGTGGATTAGAAAAAGAAAATATACAGCATTCCCAGATGCTTATAAGCCAGAAAACATAAAGGTA
ATAGCAAATGGAAAAGTTGTAGTTGACAAGGATATAAATGAGTGGATTTCAGGAAATTCAACTTATAATA
TAAAATA
Protein Sequence 
>gi|110802823|ref|YP_697384.1| phospholipase C [Clostridium perfringens SM101] MKRKICKALVCATLVTSLWAGVSTKVYAWDGKIDGTGTHAMIVTQGVSILENDMSKNEPESVRKNLEILKDNMHELQLGSTYPDYDKNAYDLYQDHFWDPDTNNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTVGCKTNEDFYADILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGNNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMAGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKVIANGKVVVDKDINEWISGNSTYNIK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: plc mutant is attenuated in mice (Awad et al., 1995).
References
Awad et al., 1995: Awad MM, Bryant AE, Stevens DL, Rood JI. Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene. Molecular microbiology. 1995; 15(2); 191-202. [PubMed: 7746141].