Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

plc from Clostridium perfringens ATCC 13124

Victor ID 1921
Gene Name plc from Clostridium perfringens ATCC 13124
Sequence Strain (Species/Organism) Clostridium perfringens ATCC 13124
NCBI Gene ID 4201274
NCBI Protein GI 110800852
Locus Tag CPF_0042
Protein Accession YP_694509.1
Other Database IDs UniProtKB-ID: PHLC_CLOP1
UniRef100: UniRef100_Q0TV31
UniRef90: UniRef90_Q0TV31
UniRef50: UniRef50_Q0TV31
UniParc: UPI000016EB37
EMBL: M24904
EMBL: X13608
EMBL: CP000246
EMBL-CDS: AAA23272.1
EMBL-CDS: CAA31943.1
EMBL-CDS: ABG84486.1
RefSeq_NT: NC_008261.1
PDB: 1QM6
PDB: 1QMD
PDB: 2WXT
PDB: 2WXU
PDB: 2WY6
GenomeReviews: CP000246_GR
KEGG: cpf:CPF_0042
TIGR: CPF_0042
OMA: GSTYPDY
ProtClustDB: CLSK566902
BioCyc: CPER195103:CPF_0042-MONOMER
Taxonomy ID 195103
Gene Starting Position 48362
Gene Ending Position 49558
Gene Strand (Orientation) +
Protein Name phospholipase C
DNA Sequence 
>gi|110798562:48362-49558 Clostridium perfringens ATCC 13124, complete genome
AATGAAAAGAAAGATTTGTAAGGCGCTTATTTGTGCCGCGCTAGCAACTAGCCTATGGGCTGGGGCATCA
ACTAAAGTCTACGCTTGGGATGGAAAGATTGATGGAACAGGAACTCATGCTATGATTGTAACTCAAGGGG
TTTCAATCTTAGAAAATGATCTGTCCAAAAATGAACCAGAAAGTGTAAGAAAAAACTTAGAGATTTTAAA
AGAGAACATGCATGAGCTTCAATTAGGTTCTACTTATCCAGATTATGATAAGAATGCATATGATCTATAT
CAAGATCATTTCTGGGATCCTGATACAGATAATAATTTCTCAAAGGATAATAGTTGGTATTTAGCTTATT
CTATACCTGACACAGGGGAATCACAAATAAGAAAATTTTCAGCATTAGCTAGATATGAATGGCAAAGAGG
AAACTATAAACAAGCTACATTCTATCTTGGAGAGGCTATGCACTATTTTGGAGATATAGATACTCCATAT
CATCCTGCTAATGTTACTGCCGTTGATAGCGCAGGACATGTTAAGTTTGAGACTTTTGCAGAGGAAAGAA
AAGAACAGTATAAAATAAACACAGCAGGTTGCAAAACTAATGAGGCTTTTTATACTGATATCTTAAAAAA
CAAAGATTTTAATGCATGGTCAAAAGAATATGCAAGAGGTTTTGCTAAAACAGGAAAATCAATATACTAT
AGTCATGCTAGCATGAGTCATAGTTGGGATGATTGGGATTATGCAGCAAAGGTAACTTTAGCTAACTCTC
AAAAAGGAACAGCGGGATATATTTATAGATTCTTACACGATGTATCAGAGGGTAATGATCCATCAGTTGG
AAAGAATGTAAAAGAACTAGTAGCTTACATATCAACTAGTGGTGAGAAAGATGCTGGAACAGATGACTAC
ATGTATTTTGGAATCAAAACAAAGGATGGAAAAACTCAAGAATGGGAAATGGACAACCCAGGAAATGATT
TTATGACTGGAAGTAAAGACACTTATACTTTCAAATTAAAAGATGAAAATCTAAAAATTGATGATATACA
AAATATGTGGATTAGAAAAAGAAAATATACAGCATTCTCAGATGCTTATAAGCCAGAAAACATAAAGATA
ATAGCAAATGGAAAAGTTGTAGTGGACAAAGATATAAACGAGTGGATTTCAGGAAATTCAACTTATAATA
TAAAATA
Protein Sequence 
>gi|110800852|ref|YP_694509.1| phospholipase C [Clostridium perfringens ATCC 13124] MKRKICKALICAALATSLWAGASTKVYAWDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFSDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: plc mutant is attenuated in mice (Awad et al., 1995).
References
Awad et al., 1995: Awad MM, Bryant AE, Stevens DL, Rood JI. Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene. Molecular microbiology. 1995; 15(2); 191-202. [PubMed: 7746141].