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M

Victor ID 1915
Gene Name M
Sequence Strain (Species/Organism) Measles virus
NCBI Gene ID 1489803
NCBI Protein GI 9626949
Locus Tag MeVgp3
Protein Accession NP_056921.1
Other Database IDs UniProtKB-ID: Q786M4_9PARA
UniRef100: UniRef100_Q9W850
UniRef90: UniRef90_P16628
UniRef50: UniRef50_P16628
UniParc: UPI00000F31F3
EMBL: DQ227321
EMBL: DQ227319
EMBL: GQ376026
EMBL: AB002686
EMBL: AB012948
EMBL: AB012949
EMBL: AB481087
EMBL: AB481088
EMBL-CDS: ABB71644.1
EMBL-CDS: ABB71660.1
EMBL-CDS: ACU57141.1
EMBL-CDS: BAA31333.1
EMBL-CDS: BAA33870.1
EMBL-CDS: BAA33876.1
EMBL-CDS: BAH96583.1
EMBL-CDS: BAH96591.1
RefSeq_NT: NC_001498.1
Taxonomy ID 11234
Gene Starting Position 3437
Gene Ending Position 4444
Gene Strand (Orientation) +
Protein Name matrix protein
DNA Sequence 
>gi|9626945:3437-4444 Measles virus, complete genome
AATGACAGAGATCTACGATTTCGACAAGTCGGCATGGGACATCAAAGGGTCGATCGCTCCGATACAACCT
ACCACCTACAGTGATGGCAGGCTGGTGCCCCAGGTCAGAGTCATAGATCCTGGTCTAGGTGATAGGAAGG
ATGAATGCTTTATGTACATGTTTCTGCTGGGGGTTGTTGAGGACAGCGATCCCCTAGGGCCTCCAATCGG
GCGAGCATTCGGGTCCCTGCCCTTAGGTGTTGGTAGATCCACAGCAAAACCCGAGGAACTCCTCAAAGAG
GCCACTGAGCTTGACATAGTTGTTAGACGTACAGCAGGGCTCAATGAAAAACTGGTGTTCTACAACAACA
CCCCACTAACCCTCCTCACACCTTGGAGAAAGGTCCTAACAACAGGGAGTGTCTTCAATGCAAACCAAGT
GTGCAATGCGGTTAATCTAATACCGCTGGACACCCCGCAGAGGTTCCGTGTTGTTTATATGAGCATCACC
CGTCTTTCGGATAACGGGTATTACACCGTTCCCAGAAGAATGCTGGAATTCAGATCGGTCAATGCAGTGG
CCTTCAACCTGCTAGTGACCCTTAGGATTGACAAGGCGATTGGCCCTGGGAAGATCATCGACAATGCAGA
GCAACTTCCTGAGGCAACATTTATGGTCCACATCGGGAACTTCAGGAGAAAGAAGAGTGAAGTCTACTCT
GCCGATTATTGCAAAATGAAAATCGAAAAGATGGGCCTGGTTTTTGCACTTGGTGGGATAGGGGGCACCA
GTCTTCACATTAGAAGCACAGGCAAAATGAGCAAGACTCTCCATGCACAACTCGGGTTCAAGAAGACCTT
ATGTTACCCACTGATGGATATCAATGAAGACCTTAATCGGTTACTCTGGAGGAGCAGATGCAAGATAGTA
AGAATCCAGGCAGTTTTGCAGCCATCAGTTCCTCAAGAATTCCGCATTTACGACGACGTGATCATAAATG
ATGACCAAGGACTATTCAAAGTTCTGTA
Protein Sequence 
>gi|9626949|ref|NP_056921.1| matrix protein [Measles virus] MTEIYDFDKSAWDIKGSIAPIQPTTYSDGRLVPQVRVIDPGLGDRKDECFMYMFLLGVVEDSDPLGPPIGRAFGSLPLGVGRSTAKPEELLKEATELDIVVRRTAGLNEKLVFYNNTPLTLLTPWRKVLTTGSVFNANQVCNAVNLIPLDTPQRFRVVYMSITRLSDNGYYTVPRRMLEFRSVNAVAFNLLVTLRIDKAIGPGKIIDNAEQLPEATFMVHIGNFRRKKSEVYSADYCKMKIEKMGLVFALGGIGGTSLHIRSTGKMSKTLHAQLGFKKTLCYPLMDINEDLNRLLWRSRCKIVRIQAVLQPSVPQEFRIYDDVIINDDQGLFKVL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The M gene from the attenuated Edmonston strain replaced the M protein of a virulent clinical isolate IC-B of the measles virus and grown in Vero cells. The recombinant viruses had had growth disadvantage in CD150-positive lymphoid B95a cells compared to the wild type IC-B (Tahara et al., 2005).
References
Tahara et al., 2005: Tahara M, Takeda M, Yanagi Y. Contributions of matrix and large protein genes of the measles virus edmonston strain to growth in cultured cells as revealed by recombinant viruses. Journal of virology. 2005; 79(24); 15218-15225. [PubMed: 16306593].