Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

E3L

Victor ID 1910
Gene Name E3L
Sequence Strain (Species/Organism) Vaccinia virus
NCBI Gene ID 3707592
NCBI Protein GI 66275856
Locus Tag VACWR059
Protein Accession YP_232941.1
Other Database IDs UniProtKB-ID: VE03_VACCW
UniRef100: UniRef100_P21605
UniRef90: UniRef90_P21081
UniRef50: UniRef50_P21605
UniParc: UPI00001382C9
EMBL: M36339
EMBL-CDS: AAB59823.1
RefSeq_NT: NC_006998.1
DIP: DIP-2175N
MINT: MINT-130721
Taxonomy ID 10245
Gene Starting Position 47779
Gene Ending Position 48351
Gene Strand (Orientation) -
Protein Name temporal expression: early
DNA Sequence 
>gi|66275797:47779-48351 Vaccinia virus, complete genome
ATCAGAATCTAATGATGACGTAACCAAGAAGTTTATCTACTGCCAATTTAGCTGCATTATTTTTAGCATC
TCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCGATGTCTACACAGGCATAAAATGTAGGA
GAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTAATTTGGCAGTACTCATTAA
TAACGGTGACAGGGTTAGCACCTTTCCAATCAATAATTTTTTTAGCCGGAATAACATCATCAAAAGACTT
ATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATGACGTCAGCCATAGCATCAGCATCC
GGCTTATCCGCCTCCGTTGTCATAAACCAACGAGGAGGAATATCGTCGGAGCTGTACACCATAGCACTAC
GTTGAAGATCGTACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTCTAGTTAGTTGTGCAGC
AGTAGCTCCTTCGATTCCAATGGTTTTAATAGCCTCACACACAATCTCTGCGTTAGAACGCTCGTCGATA
TAGATTTTAGACA
Protein Sequence 
>gi|66275856|ref|YP_232941.1| double-stranded RNA binding protein [Vaccinia virus] MSKIYIDERSNAEIVCEAIKTIGIEGATAAQLTRQLNMEKREVNKALYDLQRSAMVYSSDDIPPRWFMTTEADKPDADAMADVIIDDVSREKSMREDHKSFDDVIPAKKIIDWKGANPVTVINEYCQITRRDWSFRIESVGPSNSPTFYACVDIDGRVFDKADGKSKRDAKNNAAKLAVDKLLGYVIIRF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VVDeltaE3L mutant is apathogenic in mice (Brandt and Jacobs, 2001).
References
Brandt and Jacobs, 2001: Brandt TA, Jacobs BL. Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model. Journal of virology. 2001; 75(2); 850-856. [PubMed: 11134298].