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fadD33 from Mycobacterium tuberculosis H37Ra

Victor ID 1907
Gene Name fadD33 from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5215636
NCBI Protein GI 148661134
Locus Tag MRA_1353
Protein Accession YP_001282657.1
Other Database IDs UniProtKB-ID: A5U245_MYCTA
UniRef100: UniRef100_P0A4X9
UniRef90: UniRef90_P0A4X9
UniRef50: UniRef50_Q1BBA2
UniParc: UPI000012A5C7
EMBL: CP000611
EMBL-CDS: ABQ73095.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000065823.
EnsemblGenome_TRS: EBMYCT00000065828
EnsemblGenome_PRO: EBMYCP00000063938
GenomeReviews: CP000611_GR
KEGG: mra:MRA_1353
eggNOG: COG0318
HOGENOM: HBG547964
OMA: GENSARP
ProtClustDB: PRK05851
BioCyc: MTUB419947:MRA_1353-MONOMER
Taxonomy ID 419947
Gene Starting Position 1510590
Gene Ending Position 1512155
Gene Strand (Orientation) +
Protein Name acyl-CoA synthetase
DNA Sequence 
>gi|148659757:1510590-1512155 Mycobacterium tuberculosis H37Ra, complete genome
GATGAGTGAGCTCGCGGCCGTGCTCACGCGGTCCATGCAGGCCTCTGCCGGCGACTTGATGGTCCTCGAC
CGCGAGACCTCGCTGTGGTGTCGGCACCCGTGGCCCGAGGTACACGGGCTGGCCGAGAGCGTAGCGGCCT
GGCTGCTAGACCATGACCGACCCGCCGCGGTGGGTCTGGTCGGCGAACCGACGGTCGAGTTGGTCGCCGC
GATCCAGGGTGCCTGGCTTGCCGGCGCTGCCGTGTCGATCCTGCCCGGGCCGGTACGTGGCGCCAATGAC
CAGCGATGGGCGGACGCGACGTTGACCCGTTTCCTCGGGATTGGGGTGCGCACCGTATTGAGCCAGGGTT
CCTACCTTGCCCGCCTGCGATCGGTCGATACGGCCGGCGTAACGATCGGAGATCTCAGCACGGCGGCGCA
CACCAATCGTTCGGCCACACCGGTGGCGAGTGAAGGGCCCGCGGTCCTTCAAGGTACCGCGGGATCGACG
GGCGCGCCCCGTACCGCCATCCTTTCGCCGGGCGCGGTGCTCAGCAACTTGCGTGGGCTCAATCAGCGCG
TGGGCACCGATGCTGCGACCGACGTCGGTTGCTCATGGTTACCGCTGTACCACGACATGGGGCTCGCTTT
CGTGCTCTCTGCTGCGCTGGCCGGTGCGCCGCTCTGGTTGGCCCCGACGACGGCGTTCACGGCGTCGCCG
TTCCGTTGGTTGAGTTGGCTCTCGGACAGTGGTGCCACCATGACCGCGGCACCGAACTTCGCCTACAACC
TCATCGGCAAATACGCCAGGCGGGTATCCGAGGTCGACCTGGGTGCCCTGCGAGTGACGCTCAACGGTGG
AGAGCCGGTTGACTGCGATGGGCTGACGCGGTTCGCGGAGGCGATGGCACCGTTCGGATTCGATGCCGGC
GCCGTGTTGCCCTCCTACGGGCTCGCCGAGTCGACGTGCGCGGTGACCGTGCCGGTCCCCGGAATTGGGT
TGCTTGCCGACCGTGTCATCGACGGCAGCGGTGCGCATAAGCACGCGGTCCTGGGTAACCCCATCCCCGG
TATGGAGGTACGGATCTCGTGCGGTGATCAGGCGGCAGGCAATGCGAGCCGTGAAATTGGCGAAATCGAG
ATTCGCGGTGCGTCGATGATGGCGGGTTACCTGGGTCAGCAGCCGATCGACCCTGACGATTGGTTTGCCA
CCGGCGACCTCGGCTATCTTGGCGCTGGCGGCCTGGTGGTGTGTGGTCGCGCGAAGGAAGTCATCTCCAT
CGCGGGACGCAACATCTTTCCGACGGAGGTCGAGCTGGTGGCAGCGCAAGTTCGCGGAGTGCGCGAAGGC
GCCGTGGTCGCCTTGGGCACCGGTGATCGCTCGACCCGCCCCGGTCTGGTGGTCGCGGCCGAGTTCCGCG
GCCCAGACGAGGCGAACGCCCGCGCCGAACTGATCCAACGCGTTGCGTCCGAGTGCGGTATCGTCCCGTC
CGACGTCGTCTTCGTGTCGCCTGGATCACTGCCCCGGACGTCGTCTGGAAAACTGCGCCGCTTGGCAGTC
CGGCGCTCCCTGGAGATGGCGGACTG
Protein Sequence 
>gi|148661134|ref|YP_001282657.1| long-chain-fatty-acid--[acyl-carrier-protein] ligase [Mycobacterium tuberculosis H37Ra] MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fadD33 mutant is attenuated in mice (Rindi et al., 2002).
COG COG0318IQ, under I: Lipid transport and metabolism; Q: Secondary metabolites biosynthesis, transport and catabolism
References
Rindi et al., 2002: Rindi L, Fattorini L, Bonanni D, Iona E, Freer G, Tan D, Dehò G, Orefici G, Garzelli C. Involvement of the fadD33 gene in the growth of Mycobacterium tuberculosis in the liver of BALB/c mice. Microbiology (Reading, England). 2002; 148(Pt 12); 3873-3880. [PubMed: 12480891].