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moeB1 from Mycobacterium tuberculosis H37Ra

Victor ID 1904
Gene Name moeB1 from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5215558
NCBI Protein GI 148663066
Locus Tag MRA_3244
Protein Accession YP_001284589.1
Other Database IDs UniProtKB-ID: A5U7M7_MYCTA
UniRef100: UniRef100_Q7D5X9
UniRef90: UniRef90_Q7D5X9
UniRef50: UniRef50_Q7D5X9
UniParc: UPI00000D5E19
EMBL: CP000611
EMBL-CDS: ABQ75027.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000066157.
EnsemblGenome_TRS: EBMYCT00000066162
EnsemblGenome_PRO: EBMYCP00000064272
GenomeReviews: CP000611_GR
KEGG: mra:MRA_3244
eggNOG: COG0476
HOGENOM: HBG535305
OMA: IHGTSWV
ProtClustDB: PRK07878
BioCyc: MTUB419947:MRA_3244-MONOMER
Taxonomy ID 419947
Gene Starting Position 3593313
Gene Ending Position 3594491
Gene Strand (Orientation) -
Protein Name molybdopterin biosynthesis-like protein MoeZ
DNA Sequence 
>gi|148659757:3593313-3594491 Mycobacterium tuberculosis H37Ra, complete genome
CCTAGTACATCACCATGTCGGGCTGCATCTGCTTGGCCCACGCGACGATCCCACCCTGCAGGTGTACCGC
GTCGGAGAAACCGGCTTTCTTGACCGCAGCCAATGCCTCGGCCGAGCGCACGCCCGTCTTGCAGTACAGC
ACGGCGGTGCGGTCCTGGGGGAGCTTGGCCAGACCCTCACCCGAGTTGATCAACGATTTCGGAATCAGTT
GGGCTCCGTCGATATGCACGATGTCCCACTCCACGGGATCGCGAACGTCGATCAGTGCCAGCTTACGGCC
GGAGTCCAGCCAGTCGCGCAGCTCGCGCGGCGTGATGGTGGAACCTTTGGCCGCCTGGGCGGCATCGTCA
GCAACCACGCCGCAGAACTGTTCGTAGTCGACCAGCTCGGTGATCTTCGGTGTCGATGGGTCCTTGCGGA
TGGTGATCGTGCGATAGCTCATCTCCAGCGCGTCGTACACCAGCAACCGGCCAAGCAGTGTTTCACCTAT
CCCGGTGATCAGCTTGATCGCCTCAGTGCCCATCACCGATGCGACCGAGGCACAGATAATGCCCAGCACC
CCGCCTTCAGCACAGGACGGCACCATGCCCGGCGGCGGCGGCTCGGGATACAGGTCGCGGTAGTTGACAC
CCAACCCGTCGGGGGCGTCCTCCCAAAACACCGATGCCTGGCCCTCGAAGCGGTAAATCGACCCCCACAC
GTACGGCTTGCCAGCCAGCACCGCGGCGTCGTTGACCAGATACCGGGTGGCGAAGTTGTCGGTGCCATCC
AAGATCAGGTCGTACTGCTTGAACAGGTCGACGGCGTTGCTCGGCGCAAGCCGCAGCTCGTGTAGTCGCA
CCCGGATCAGCGGGTTGATCGCGACAATCGAATCGCGCGCCGACTGAGCCTTGGAGCGCCCGACGTCAGC
TACCCCATGGATGACCTGGCGCTGCAGGTTCGACTCGTCAACCACATCGAAGTCGACGATGCCGATGGTG
CCGACGCCGGCGGCGGCCAGATACAATAACGTGGGCGCTCCGAGCCCGCCGGCGCCGATCACCAGTACTC
GCGCGTTCTTGAGCCTCTTCTGCCCGTCAACACCCAGGTCAGGAATGATGAGATGGCGGCTGTAGCGAGC
TACCTCTTCACGGCTGAGCGCGGATGCTGGCTCAACTAGTGGCGGCAAGGATGTCGACA
Protein Sequence 
>gi|148663066|ref|YP_001284589.1| molybdopterin biosynthesis-like protein MoeZ [Mycobacterium tuberculosis H37Ra] MSTSLPPLVEPASALSREEVARYSRHLIIPDLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGIVDFDVVDESNLQRQVIHGVADVGRSKAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQYDLILDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAPDGLGVNYRDLYPEPPPPGMVPSCAEGGVLGIICASVASVMGTEAIKLITGIGETLLGRLLVYDALEMSYRTITIRKDPSTPKITELVDYEQFCGVVADDAAQAAKGSTITPRELRDWLDSGRKLALIDVRDPVEWDIVHIDGAQLIPKSLINSGEGLAKLPQDRTAVLYCKTGVRSAEALAAVKKAGFSDAVHLQGGIVAWAKQMQPDMVMY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: moeB1 mutant is attenuated in mice (MacGurn and Cox, 2007).
COG COG0476H, under H: Coenzyme transport and metabolism
References
MacGurn and Cox, 2007: MacGurn JA, Cox JS. A genetic screen for Mycobacterium tuberculosis mutants defective for phagosome maturation arrest identifies components of the ESX-1 secretion system. Infection and immunity. 2007; 75(6); 2668-2678. [PubMed: 17353284].