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phoP from Mycobacterium tuberculosis H37Ra

Victor ID 1899
Gene Name phoP from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5215306
NCBI Protein GI 148660534
Locus Tag MRA_0767
Protein Accession YP_001282057.1
Other Database IDs UniProtKB-ID: A5U0E5_MYCTA
UniRef100: UniRef100_A5U0E5
UniRef90: UniRef90_A1KGP0
UniRef50: UniRef50_A0PWB4
UniParc: UPI0001534069
EMBL: CP000611
EMBL-CDS: ABQ72495.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000067470.
EnsemblGenome_TRS: EBMYCT00000067475
EnsemblGenome_PRO: EBMYCP00000065585
GenomeReviews: CP000611_GR
KEGG: mra:MRA_0767
eggNOG: COG0745
HOGENOM: HBG753323
OMA: VHTATNG
ProtClustDB: CLSK790716
BioCyc: MTUB419947:MRA_0767-MONOMER
Taxonomy ID 419947
Gene Starting Position 852913
Gene Ending Position 853656
Gene Strand (Orientation) +
Protein Name putative two component system response transcriptional positive regulator PhoP
DNA Sequence 
>gi|148659757:852913-853656 Mycobacterium tuberculosis H37Ra, complete genome
AATGCGGAAAGGGGTTGATCTCGTGACGGCGGGAACCCCAGGCGAAAACACCACACCGGAGGCTCGTGTC
CTCGTGGTCGATGATGAGGCCAACATCGTTGAACTGCTGTCGGTGAGCCTCAAGTTCCAGGGCTTTGAAG
TCTACACCGCGACCAACGGGGCACAGGCGCTGGATCGGGCCCGGGAAACCCGGCCGGACGCGGTGATCCT
CGATGTGATGATGCCCGGGATGGACGGCTTTGGGGTGCTGCGCCGGCTGCGCGCCGACGGCATCGATGCC
CCGGCGTTGTTCCTGACGGCCCGTGACTCGCTACAGGACAAGATCGCGGGTCTGACCCTGGGTGGTGACG
ACTATGTGACAAAGCCCTTCAGTTTGGAGGAGGTCGTGGCCAGGCTGCGGGTCATCCTGCGACGCGCGGG
CAAGGGCAACAAGGAACCACGTAATGTTCGACTGACGTTCGCCGATATCGAGCTCGACGAGGAGACCCAC
GAAGTGTGGAAGGCGGGCCAACCGGTGTCGCTGTCGCCCACCGAATTCACCCTGCTGCGCTATTTCGTGA
TCAACGCGGGCACCGTGCTGAGCAAGCCTAAGATTCTCGACCACGTTTGGCGCTACGACTTCGGTGGTGA
TGTCAACGTCGTCGAGTCCTACGTGTTGTATCTGCGCCGCAAGATCGACACTGGGGAGAAGCGGCTGCTG
CACACGCTGCGCGGGGTGGGCTACGTACTGCGGGAGCCTCGATG
Protein Sequence 
>gi|148660534|ref|YP_001282057.1| two component system response transcriptional positive regulator PhoP [Mycobacterium tuberculosis H37Ra] MRKGVDLVTAGTPGENTTPEARVLVVDDEANIVELLSVSLKFQGFEVYTATNGAQALDRARETRPDAVILDVMMPGMDGFGVLRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGKGNKEPRNVRLTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILDHVWRYDFGGDVNVVESYVLYLRRKIDTGEKRLLHTLRGVGYVLREPR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: phoP mutant is attenuated in mice (Pérez et al., 2001).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Pérez et al., 2001: Pérez E, Samper S, Bordas Y, Guilhot C, Gicquel B, Martín C. An essential role for phoP in Mycobacterium tuberculosis virulence. Molecular microbiology. 2001; 41(1); 179-187. [PubMed: 11454210].