Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

lspA from Mycobacterium tuberculosis H37Ra

Victor ID 1896
Gene Name lspA from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5214891
NCBI Protein GI 148661335
Locus Tag MRA_1551
Protein Accession YP_001282858.1
Other Database IDs UniProtKB-ID: A5U2P6_MYCTA
UniRef100: UniRef100_A1KIW9
UniRef90: UniRef90_A1KIW9
UniRef50: UniRef50_A1KIW9
UniParc: UPI000012E97D
EMBL: CP000611
EMBL-CDS: ABQ73296.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000065591.
EnsemblGenome_TRS: EBMYCT00000065596
EnsemblGenome_PRO: EBMYCP00000063706
GenomeReviews: CP000611_GR
KEGG: mra:MRA_1551
eggNOG: COG0597
HOGENOM: HBG724422
OMA: SMKVGDS
ProtClustDB: PRK14764
BioCyc: MTUB419947:MRA_1551-MONOMER
Taxonomy ID 419947
Gene Starting Position 1743760
Gene Ending Position 1744368
Gene Strand (Orientation) +
Protein Name lipoprotein signal peptidase
DNA Sequence 
>gi|148659757:1743760-1744368 Mycobacterium tuberculosis H37Ra, complete genome
TGTGCCTGACGAACCAACAGGATCGGCTGATCCGCTGACCTCGACCGAGGAAGCCGGGGGGGCGGGGGAA
CCTAACGCTCCCGCGCCGCCGCGACGGCTGCGCATGCTGCTGTCGGTCGCTGTGGTGGTGCTCACACTCG
ACATTGTCACCAAGGTGGTAGCTGTCCAACTGTTGCCGCCCGGCCAGCCGGTGTCGATTATCGGCGACAC
GGTGACCTGGACTCTGGTGCGTAATTCTGGGGCGGCCTTCTCGATGGCGACCGGATACACCTGGGTTTTG
ACGCTGATTGCGACGGGTGTCGTGGTCGGAATTTTCTGGATGGGGCGGCGGCTGGTATCGCCGTGGTGGG
CGCTGGGTCTTGGGATGATCCTGGGCGGTGCCATGGGCAACCTGGTTGATCGCTTCTTTCGGGCACCGGG
GCCGCTGCGCGGGCACGTCGTCGATTTCTTGTCGGTCGGCTGGTGGCCGGTGTTCAATGTCGCCGATCCG
TCGGTAGTCGGTGGCGCCATCCTGCTGGTCATCCTGTCGATCTTTGGCTTTGACTTCGACACCGTAGGTC
GGCGACACGCCGACGGGGACACCGTAGGTCGGCGCAAAGCCGATGGCTG
Protein Sequence 
>gi|148661335|ref|YP_001282858.1| lipoprotein signal peptidase [Mycobacterium tuberculosis H37Ra] MPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLSVAVVVLTLDIVTKVVAVQLLPPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lspA mutant is attenuated in mice (Rampini et al., 2008).
COG COG0597MU, under M: Cell wall/membrane/envelope biogenesis; U: Intracellular trafficking, secretion, and vesicular transport
References
Rampini et al., 2008: Rampini SK, Selchow P, Keller C, Ehlers S, Böttger EC, Sander P. LspA inactivation in Mycobacterium tuberculosis results in attenuation without affecting phagosome maturation arrest. Microbiology (Reading, England). 2008; 154(Pt 10); 2991-3001. [PubMed: 18832305].