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ompA from Mycobacterium tuberculosis H37Ra

Victor ID 1895
Gene Name ompA from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5214708
NCBI Protein GI 148660677
Locus Tag MRA_0906
Protein Accession YP_001282200.1
Other Database IDs UniProtKB-ID: A5U0T8_MYCTA
UniRef100: UniRef100_P65593
UniRef90: UniRef90_P65593
UniRef50: UniRef50_P65593
UniParc: UPI0000139DDD
EMBL: CP000611
EMBL-CDS: ABQ72638.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000065000.
EnsemblGenome_TRS: EBMYCT00000065005
EnsemblGenome_PRO: EBMYCP00000063115
GenomeReviews: CP000611_GR
KEGG: mra:MRA_0906
eggNOG: COG2885
HOGENOM: HBG565454
OMA: VERDTIT
ProtClustDB: CLSK790818
BioCyc: MTUB419947:MRA_0906-MONOMER
Taxonomy ID 419947
Gene Starting Position 1004118
Gene Ending Position 1005098
Gene Strand (Orientation) +
Protein Name outer membrane protein A
DNA Sequence 
>gi|148659757:1004118-1005098 Mycobacterium tuberculosis H37Ra, complete genome
AGTGGCTTCTAAGGCGGGTTTGGGCCAAACACCCGCGACCACCGACGCGCGACGAACTCAGAAATTCTAC
CGGGGCTCGCCGGGCCGTCCGTGGCTGATTGGCGCGGTGGTTATTCCGTTGCTGATAGCGGCAATCGGTT
ACGGTGCATTCGAGCGGCCCCAGTCCGTTACCGGACCGACCGGTGTGTTGCCGACACTGACACCGACCAG
CACCCGGGGCGCTTCTGCGTTGTCCTTGTCTTTGCTGTCAATTAGCCGCAGCGGCAACACCGTTACTCTG
ATCGGTGACTTCCCCGATGAGGCCGCCAAGGCGGCCTTGATGACGGCGCTCAACGGCTTGCTTGCTCCGG
GCGTGAACGTCATCGACCAGATTCACGTCGATCCCGTTGTGCGATCACTTGATTTCTCAAGTGCGGAACC
AGTTTTCACCGCCAGCGTGCCGATTCCTGATTTTGGCCTCAAAGTCGAAAGGGACACCGTCACCTTGACC
GGAACTGCCCCTTCATCCGAGCACAAGGACGCAGTGAAGCGCGCGGCGACCAGCACCTGGCCTGACATGA
AAATCGTTAACAATATTGAGGTTACGGGGCAGGCACCGCCAGGACCCCCGGCCTCCGGCCCATGTGCCGA
CCTGCAATCAGCCATCAATGCCGTGACGGGTGGACCCATCGCGTTTGGCAACGACGGGGCTAGTCTGATC
CCAGCCGACTATGAAATCCTGAACCGGGTAGCCGACAAGCTCAAGGCATGTCCGGACGCTCGGGTGACGA
TCAACGGCTACACCGACAACACCGGCAGCGAAGGTATCAATATCCCGTTGAGCGCTCAGCGAGCCAAGAT
AGTCGCCGACTACCTGGTTGCCCGCGGAGTTGCCGGCGATCACATTGCCACCGTGGGTCTCGGTTCGGTG
AATCCGATCGCCAGCAACGCCACACCCGAGGGGCGCGCCAAGAATCGTCGCGTCGAGATCGTGGTCAACT
A
Protein Sequence 
>gi|148660677|ref|YP_001282200.1| outer membrane protein A [Mycobacterium tuberculosis H37Ra] MASKAGLGQTPATTDARRTQKFYRGSPGRPWLIGAVVIPLLIAAIGYGAFERPQSVTGPTGVLPTLTPTSTRGASALSLSLLSISRSGNTVTLIGDFPDEAAKAALMTALNGLLAPGVNVIDQIHVDPVVRSLDFSSAEPVFTASVPIPDFGLKVERDTVTLTGTAPSSEHKDAVKRAATSTWPDMKIVNNIEVTGQAPPGPPASGPCADLQSAINAVTGGPIAFGNDGASLIPADYEILNRVADKLKACPDARVTINGYTDNTGSEGINIPLSAQRAKIVADYLVARGVAGDHIATVGLGSVNPIASNATPEGRAKNRRVEIVVN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ompA mutant is impaired in its ability to grow in macrophages and in normal mice, although it was as virulent as the wild type in mice that lack T cells (Raynaud et al., 2002).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Raynaud et al., 2002: Raynaud C, Papavinasasundaram KG, Speight RA, Springer B, Sander P, Böttger EC, Colston MJ, Draper P. The functions of OmpATb, a pore-forming protein of Mycobacterium tuberculosis. Molecular microbiology. 2002; 46(1); 191-201. [PubMed: 12366842].