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esxA from Mycobacterium tuberculosis H37Ra

Victor ID 1889
Gene Name esxA from Mycobacterium tuberculosis H37Ra
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5214549
NCBI Protein GI 148663742
Locus Tag MRA_3914
Protein Accession YP_001285265.1
Other Database IDs UniProtKB-ID: A5U9K3_MYCTA
UniRef100: UniRef100_P0A565
UniRef90: UniRef90_P0A565
UniRef50: UniRef50_P0A565
UniParc: UPI0000036DD3
EMBL: CP000611
EMBL-CDS: ABQ75703.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000065116.
EnsemblGenome_TRS: EBMYCT00000065121
EnsemblGenome_PRO: EBMYCP00000063231
GenomeReviews: CP000611_GR
KEGG: mra:MRA_3914
eggNOG: COG4842
HOGENOM: HBG569144
OMA: NTEGINH
ProtClustDB: CLSK800028
BioCyc: MTUB419947:MRA_3914-MONOMER
Taxonomy ID 419947
Gene Starting Position 4361054
Gene Ending Position 4361341
Gene Strand (Orientation) +
Protein Name early secretory antigenic target EsxA
DNA Sequence 
>gi|148659757:4361054-4361341 Mycobacterium tuberculosis H37Ra, complete genome
CATGACAGAGCAGCAGTGGAATTTCGCGGGTATCGAGGCCGCGGCAAGCGCAATCCAGGGAAATGTCACG
TCCATTCATTCCCTCCTTGACGAGGGGAAGCAGTCCCTGACCAAGCTCGCAGCGGCCTGGGGCGGTAGCG
GTTCGGAGGCGTACCAGGGTGTCCAGCAAAAATGGGACGCCACGGCTACCGAGCTGAACAACGCGCTGCA
GAACCTGGCGCGGACGATCAGCGAAGCCGGTCAGGCAATGGCTTCGACCGAAGGCAACGTCACTGGGATG
TTCGCATA
Protein Sequence 
>gi|148663742|ref|YP_001285265.1| early secretory antigenic target EsxA [Mycobacterium tuberculosis H37Ra] MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMFA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: esxA (ESAT-6) mutant is attenuated in mice (Fortune et al., 2005).
COG COG4842S, under S: Function unknown
References
Fortune et al., 2005: Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ. Mutually dependent secretion of proteins required for mycobacterial virulence. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(30); 10676-10681. [PubMed: 16030141].