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mmpL7

Victor ID 1877
Gene Name mmpL7
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Ra
NCBI Gene ID 5213528
NCBI Protein GI 148662788
Locus Tag MRA_2968
Protein Accession YP_001284311.1
Other Database IDs UniProtKB-ID: A5U6U9_MYCTA
UniRef100: UniRef100_P65371
UniRef90: UniRef90_P65371
UniRef50: UniRef50_P65371
UniParc: UPI0000036B91
EMBL: CP000611
EMBL-CDS: ABQ74749.1
RefSeq_NT: NC_009525.1
EnsemblGenome: EBMYCG00000068048.
EnsemblGenome_TRS: EBMYCT00000068053
EnsemblGenome_PRO: EBMYCP00000066163
GenomeReviews: CP000611_GR
KEGG: mra:MRA_2968
eggNOG: COG2409
HOGENOM: HBG568927
OMA: ISTEAPI
ProtClustDB: CLSK792178
BioCyc: MTUB419947:MRA_2968-MONOMER
Taxonomy ID 419947
Gene Starting Position 3297061
Gene Ending Position 3299823
Gene Strand (Orientation) +
Protein Name transmembrane transport protein MmpL7
DNA Sequence 
>gi|148659757:3297061-3299823 Mycobacterium tuberculosis H37Ra, complete genome
GATGCCTAGTCCGGCTGGCCGTCTACACAGAATTCGGTATATCCGTTTGAAAAAGTCCTCCCCGGACTGC
CGCGCCACCATCACCAGCGGGTCAGCCGACGGTCAGCGAAGGTCACCCCGGCTCACCAACCTGCTCGTCG
TCGCCGCCTGGGTTGCCGCGGCGGTGATCGCAAATCTGCTTCTCACGTTCACGCAAGCAGAACCGCACGA
CACCAGCCCGGCGCTGCTGCCACAAGATGCCAAGACAGCCGCCGCCACCAGCCGGATTGCGCAGGCTTTC
CCCGGCACCGGTAGCAACGCTATCGCCTATCTCGTCGTGGAAGGCGGCAGCACGCTTGAGCCGCAGGACC
AGCCTTACTACGACGCCGCCGTCGGTGCCCTGCGCGCCGACACCCGCCACGTGGGATCCGTCCTCGACTG
GTGGTCAGATCCCGTCACCGCCCCGCTGGGAACCAGCCCCGACGGCCGCTCCGCTACGGCCATGGTGTGG
CTGCGGGGCGAGGCGGGCACCACCCAAGCTGCCGAATCCCTCGATGCCGTCCGATCGGTGCTGCGCCAGT
TACCGCCCAGTGAGGGGCTTCGCGCCAGCATCGTGGTCCCGGCAATCACCAACGACATGCCGATGCAGAT
AACCGCCTGGCAGAGCGCGACGATCGTGACCGTTGCGGCGGTGATCGCCGTCCTACTGCTGCTGCGGGCG
CGCCTGTCGGTGCGGGCCGCGGCGATCGTGCTGCTGACCGCGGACTTGTCGCTTGCGGTGGCCTGGCCGC
TGGCCGCGGTGGTGCGGGGACACGATTGGGGAACCGATTCGGTATTTTCTTGGACGCTGGCCGCGGTCCT
GACGATCGGAACCATCACCGCAGCCACCATGCTGGCCGCGCGGCTCGGGTCCGACGCAGGTCATTCGGCC
GCGCCCACATACCGCGACAGCCTGCCCGCGTTCGCCCTGCCCGGGGCGTGTGTCGCCATATTCACCGGCC
CGCTGCTGCTGGCCCGAACCCCAGCGCTGCACGGAGTTGGCACTGCCGGGCTAGGTGTCTTTGTGGCACT
TGCGGCTTCGTTGACGGTGCTGCCTGCCCTGATCGCGCTTGCCGGAGCGTCACGGCAGTTACCGGCACCA
ACCACGGGTGCCGGCTGGACAGGCCGGTTGTCGCTACCCGTCTCTTCTGCTTCGGCCCTGGGCACAGCGG
CAGTGCTGGCGATCTGCATGCTACCCATCATCGGGATGCGGTGGGGTGTGGCCGAGAACCCGACAAGGCA
AGGCGGCGCACAAGTCCTTCCGGGGAATGCGCTTCCCGATGTGGTGGTGATCAAATCCGCTCGGGACCTG
AGGGACCCAGCCGCGCTCATCGCCATCAACCAGGTCAGCCACCGTCTGGTGGAGGTTCCCGGTGTGCGCA
AGGTGGAGTCGGCGGCATGGCCGGCCGGTGTCCCGTGGACCGACGCCTCGCTCAGTTCCGCGGCCGGCAG
GCTCGCCGACCAGCTGGGTCAGCAGGCCGGATCGTTCGTGCCGGCGGTGACTGCGATCAAATCGATGAAG
TCCATAATCGAACAGATGAGCGGCGCGGTCGACCAACTGGACAGCACCGTGAACGTGACTCTCGCCGGGG
CAAGGCAAGCACAGCAATACCTCGATCCCATGCTCGCCGCCGCGCGGAACCTCAAAAACAAAACCACCGA
ACTGTCGGAATACCTGGAAACGATCCACACCTGGATTGTCGGCTTCACAAACTGCCCCGACGACGTCCTG
TGCACGGCCATGCGCAAGGTCATTGAACCCTACGACATCGTGGTCACCGGCATGAACGAGCTGTCCACTG
GCGCCGACCGCATCTCCGCGATATCGACACAGACAATGAGCGCGTTGTCCTCGGCACCGCGGATGGTGGC
GCAGATGCGGTCGGCGCTAGCACAGGTGCGCTCGTTCGTACCCAAGCTGGAAACAACCATCCAGGACGCC
ATGCCGCAAATAGCGCAGGCGTCGGCGATGCTGAAGAATCTCAGCGCCGATTTCGCCGATACCGGTGAGG
GCGGCTTCCACCTGTCCAGGAAGGACCTGGCGGACCCGTCGTACCGGCACGTACGGGAATCGATGTTCTC
GTCAGACGGAACCGCCACCCGGCTGTTCCTCTATTCTGACGGACAACTGGACCTTGCTGCGGCAGCACGC
GCGCAGCAGCTCGAGATCGCCGCGGGCAAGGCGATGAAATACGGAAGCCTGGTCGACAGCCAGGTCACGG
TGGGTGGGGCCGCGCAAATAGCCGCGGCTGTCCGCGATGCCCTCATCCACGATGCTGTGCTACTGGCCGT
TATCTTGCTCACGGTAGTGGCTCTGGCCAGCATGTGGCGCGGTGCCGTCCACGGTGCTGCGGTTGGCGTG
GGTGTGCTGGCCTCTTACCTCGCCGCCCTGGGGGTCTCGATTGCACTGTGGCAACACCTACTGGATCGCG
AGCTCAACGCCTTGGTCCCGCTGGTGTCGTTCGCCGTCCTCGCTTCGTGCGGCGTCCCGTATCTCGTTGC
CGGCATCAAAGCCGGTCGTATCGCCGACGAGGCAACGGGTGCGCGGTCCAAGGGGGCGGTATCCGGGCGG
GGAGCGGTTGCGCCGCTTGCGGCGCTCGGTGGCGTATTCGGCGCTGGCCTGGTGCTGGTGTCGGGAGGTT
CCTTCAGCGTGCTCAGTCAGATTGGCACGGTTGTTGTGCTCGGTCTGGGCGTGCTGATCACGGTGCAGCG
AGCGTGGCTTCCGACCACGCCAGGGCGGCGTTG
Protein Sequence 
>gi|148662788|ref|YP_001284311.1| transmembrane transport protein MmpL7 [Mycobacterium tuberculosis H37Ra] MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAWVAAAVIANLLLTFTQAEPHDTSPALLPQDAKTAAATSRIAQAFPGTGSNAIAYLVVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDWWSDPVTAPLGTSPDGRSATAMVWLRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAAAIVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGSDAGHSAAPTYRDSLPAFALPGACVAIFTGPLLLARTPALHGVGTAGLGVFVALAASLTVLPALIALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVLAICMLPIIGMRWGVAENPTRQGGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESAAWPAGVPWTDASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTELSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSALSSAPRMVAQMRSALAQVRSFVPKLETTIQDAMPQIAQASAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQLDLAAAARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLAVILLTVVALASMWRGAVHGAAVGVGVLASYLAALGVSIALWQHLLDRELNALVPLVSFAVLASCGVPYLVAGIKAGRIADEATGARSKGAVSGRGAVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVLGLGVLITVQRAWLPTTPGRR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mmpL7 mutant is attenuated in mice (Cox et al., 1999).
COG COG2409R, under R: General function prediction only
References
Cox et al., 1999: Cox JS, Chen B, McNeil M, Jacobs WR Jr. Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice. Nature. 1999; 402(6757); 79-83. [PubMed: 10573420].